ROCK2, but not ROCK1 interacts with phosphorylated STAT3 and co-occupies TH17/TFH gene promoters in TH17-activated human T cells

por Chen, Wei, Nyuydzefe, Melanie S., Weiss, Jonathan M., Zhang, Jingya, Waksal, Samuel D., Zanin-Zhorov, Alexandra
Publicado 2018

Selectivity matters: selective ROCK2 inhibitor ameliorates established liver fibrosis via targeting inflammation, fibrosis, and metabolism

por Zanin-Zhorov, Alexandra, Chen, Wei, Moretti, Julien, Nyuydzefe, Melanie S., Zhorov, Iris, Munshi, Rashmi, Ghosh, Malavika, Serdjebi, Cindy, MacDonald, Kelli, Blazar, Bruce R., Palmer, Melissa, Waksal, Samuel D.
Publicado 2023

ROCK2 inhibition attenuates profibrogenic immune cell function to reverse thioacetamide-induced liver fibrosis

por Nalkurthi, Christina, Schroder, Wayne A., Melino, Michelle, Irvine, Katharine M., Nyuydzefe, Melanie, Chen, Wei, Liu, Jing, Teng, Michele W.L., Hill, Geoffrey R., Bertolino, Patrick, Blazar, Bruce R., Miller, Gregory C., Clouston, Andrew D., Zanin-Zhorov, Alexandra, MacDonald, Kelli P.A.
Publicado 2021