Toxicity screening of bisphenol A replacement compounds: cytotoxicity and mRNA expression in LMH 3D spheroids

por Sharin, Tasnia, Crump, Doug, O’Brien, Jason M.
Publicado 2022

Benzo(a)pyrene Is Mutagenic in Mouse Spermatogonial Stem Cells and Dividing Spermatogonia

por O’Brien, Jason M., Beal, Marc A., Yauk, Carole L., Marchetti, Francesco
Publicado 2016

Next generation sequencing of benzo(a)pyrene-induced lacZ mutants identifies a germ cell-specific mutation spectrum

por O’Brien, Jason M., Beal, Marc A., Yauk, Carole L., Marchetti, Francesco
Publicado 2016

A Case Study on Integrating a New Key Event Into an Existing Adverse Outcome Pathway on Oxidative DNA Damage: Challenges and Approaches in a Data-Rich Area

por Huliganga, Elizabeth, Marchetti, Francesco, O’Brien, Jason M., Chauhan, Vinita, Yauk, Carole L.
Publicado 2022

Sublinear response in lacZ mutant frequency of Muta(™)Mouse spermatogonial stem cells after low dose subchronic exposure to N‐ethyl‐N‐nitrosourea

por O'Brien, Jason M., Walker, Mike, Sivathayalan, Ahalya, Douglas, George R., Yauk, Carole L., Marchetti, Francesco
Publicado 2015

In Utero Exposure to Benzo[a]Pyrene Increases Mutation Burden in the Soma and Sperm of Adult Mice

por Meier, Matthew J., O’Brien, Jason M., Beal, Marc A., Allan, Beverly, Yauk, Carole L., Marchetti, Francesco
Publicado 2016

A Pragmatic Approach to Adverse Outcome Pathway Development and Evaluation

por Svingen, Terje, Villeneuve, Daniel L, Knapen, Dries, Panagiotou, Eleftheria Maria, Draskau, Monica Kam, Damdimopoulou, Pauliina, O’Brien, Jason M
Publicado 2021

Transgenic Rodent Assay for Quantifying Male Germ Cell Mutant Frequency

por O'Brien, Jason M., Beal, Marc A., Gingerich, John D., Soper, Lynda, Douglas, George R., Yauk, Carole L., Marchetti, Francesco
Publicado 2014

Chemically induced mutations in a MutaMouse reporter gene inform mechanisms underlying human cancer mutational signatures

por Beal, Marc A., Meier, Matthew J., LeBlanc, Danielle P., Maurice, Clotilde, O’Brien, Jason M., Yauk, Carole L., Marchetti, Francesco
Publicado 2020

Impact of sampling time on the detection of mutations in rapidly proliferating tissues using transgenic rodent gene mutation models: A review

por Douglas, George R., Beevers, Carol, Gollapudi, Bhaskar, Keig‐Shevlin, Zena, Kirkland, David, O'Brien, Jason M., van Benthem, Jan, Yauk, Carole L., Young, Robert R., Marchetti, Francesco
Publicado 2022