Transient microbiota exposures activate dormant Escherichia coli infection in the bladder and drive severe outcomes of recurrent disease

por Gilbert, Nicole M., O’Brien, Valerie P., Lewis, Amanda L.
Publicado 2017

Bladder Exposure to Gardnerella Activates Host Pathways Necessary for Escherichia coli Recurrent UTI

por O’Brien, Valerie P., Lewis, Amanda L., Gilbert, Nicole M.
Publicado 2021

Host restriction of Escherichia coli recurrent urinary tract infection occurs in a bacterial strain-specific manner

por O’Brien, Valerie P., Dorsey, Denise A., Hannan, Thomas J., Hultgren, Scott J.
Publicado 2018

Urinary Tract Infection as a Preventable Cause of Pregnancy Complications: Opportunities, Challenges, and a Global Call to Action

por Gilbert, Nicole M., O'Brien, Valerie P., Hultgren, Scott, Macones, George, Lewis, Warren G., Lewis, Amanda L.
Publicado 2013

Gardnerella Exposures Alter Bladder Gene Expression and Augment Uropathogenic Escherichia coli Urinary Tract Infection in Mice

por Gilbert, Nicole M., O’Brien, Valerie P., Waller, Chevaughn, Batourina, Ekatherina, Mendelsohn, Cathy Lee, Lewis, Amanda L.
Publicado 2022

Low-dose inoculation of Escherichia coli achieves robust vaginal colonization and results in ascending infection accompanied by severe uterine inflammation in mice

por O’Brien, Valerie P., Gilbert, Nicole M., Lebratti, Tania, Agarwal, Kavita, Foster, Lynne, Shin, Haina, Lewis, Amanda L.
Publicado 2019

Mucosal infection rewires TNFɑ signaling dynamics to skew susceptibility to recurrence

por Yu, Lu, O'Brien, Valerie P, Livny, Jonathan, Dorsey, Denise, Bandyopadhyay, Nirmalya, Colonna, Marco, Caparon, Michael G, Roberson, Elisha DO, Hultgren, Scott J, Hannan, Thomas J
Publicado 2019

Sustained Helicobacter pylori infection accelerates gastric dysplasia in a mouse model

por O’Brien, Valerie P, Koehne, Amanda L, Dubrulle, Julien, Rodriguez, Armando E, Leverich, Christina K, Kong, V Paul, Campbell, Jean S, Pierce, Robert H, Goldenring, James R, Choi, Eunyoung, Salama, Nina R
Publicado 2020

Glycan cross-feeding supports mutualism between Fusobacterium and the vaginal microbiota

por Agarwal, Kavita, Robinson, Lloyd S., Aggarwal, Somya, Foster, Lynne R., Hernandez-Leyva, Ariel, Lin, Hueylie, Tortelli, Brett A., O’Brien, Valerie P., Miller, Liza, Kau, Andrew L., Reno, Hilary, Gilbert, Nicole M., Lewis, Warren G., Lewis, Amanda L.
Publicado 2020

Single-cell Profiling Uncovers a Muc4-Expressing Metaplastic Gastric Cell Type Sustained by Helicobacter pylori-driven Inflammation

por O'Brien, Valerie P., Kang, Yuqi, Shenoy, Meera K., Finak, Greg, Young, William C., Dubrulle, Julien, Koch, Lisa, Rodriguez Martinez, Armando E., Williams, Jeffery, Donato, Elizabeth, Batra, Surinder K., Yeung, Cecilia C.S., Grady, William M., Koch, Meghan A., Gottardo, Raphael, Salama, Nina R.
Publicado 2023

Uropathogenic Escherichia coli infection-induced epithelial trained immunity impacts urinary tract disease outcome

por Russell, Seongmi K., Harrison, Jessica K., Olson, Benjamin S., Lee, Hyung Joo, O’Brien, Valerie P., Xing, Xiaoyun, Livny, Jonathan, Yu, Lu, Roberson, Elisha D. O., Bomjan, Rajdeep, Fan, Changxu, Sha, Marina, Estfanous, Shady, Amer, Amal O., Colonna, Marco, Stappenbeck, Thaddeus S., Wang, Ting, Hannan, Thomas J., Hultgren, Scott J.
Publicado 2023