The ‘Danse Macabre’—Neutrophils the Interactive Partner Affecting Oral Cancer Outcomes

por Hadjigol, Sara, Shah, Bansari A., O’Brien-Simpson, Neil M.
Publicado 2022

Editorial: Antimicrobial and Anticancer Peptides

por O'Brien-Simpson, Neil M., Hoffmann, Ralf, Chia, C. S. Brian, Wade, John D.
Publicado 2018

Development and evaluation of a saliva-based chair-side diagnostic for the detection of Porphyromonas gingivalis

por O'Brien-Simpson, Neil M., Burgess, Kate, Brammar, Gail C., Darby, Ivan B., Reynolds, Eric C.
Publicado 2015

A Rapid and Quantitative Flow Cytometry Method for the Analysis of Membrane Disruptive Antimicrobial Activity

por O’Brien-Simpson, Neil M., Pantarat, Namfon, Attard, Troy J., Walsh, Katrina A., Reynolds, Eric C.
Publicado 2016

Tumor Associated Macrophages: Origin, Recruitment, Phenotypic Diversity, and Targeting

por Hourani, Tetiana, Holden, James A., Li, Wenyi, Lenzo, Jason C., Hadjigol, Sara, O’Brien-Simpson, Neil M.
Publicado 2021

The Potential of Modified and Multimeric Antimicrobial Peptide Materials as Superbug Killers

por Matthyssen, Tamara, Li, Wenyi, Holden, James A., Lenzo, Jason C., Hadjigol, Sara, O’Brien-Simpson, Neil M.
Publicado 2022

(Re)Defining the Proline-Rich Antimicrobial Peptide Family and the Identification of Putative New Members

por Welch, Nicholas G., Li, Wenyi, Hossain, Mohammed Akhter, Separovic, Frances, O'Brien-Simpson, Neil M., Wade, John D.
Publicado 2020

Unprimed, M1 and M2 Macrophages Differentially Interact with Porphyromonas gingivalis

por Lam, Roselind S., O’Brien-Simpson, Neil M., Holden, James A., Lenzo, Jason C., Fong, Shao B., Reynolds, Eric C.
Publicado 2016

Evaluation of Potential DnaK Modulating Proline-Rich Antimicrobial Peptides Identified by Computational Screening

por Handley, Thomas N. G., Li, Wenyi, Welch, Nicholas G., O’Brien-Simpson, Neil M., Hossain, Mohammed Akhter, Wade, John D.
Publicado 2022

Label-free macrophage phenotype classification using machine learning methods

por Hourani, Tetiana, Perez-Gonzalez, Alexis, Khoshmanesh, Khashayar, Luwor, Rodney, Achuthan, Adrian A., Baratchi, Sara, O’Brien-Simpson, Neil M., Al-Hourani, Akram
Publicado 2023

The Effect of Selective D- or N(α)-Methyl Arginine Substitution on the Activity of the Proline-Rich Antimicrobial Peptide, Chex1-Arg20

por Li, Wenyi, Sun, Zhe, O'Brien-Simpson, Neil M., Otvos, Laszlo, Reynolds, Eric C., Hossain, Mohammed A., Separovic, Frances, Wade, John D.
Publicado 2017

Outer Membrane Vesicles Prime and Activate Macrophage Inflammasomes and Cytokine Secretion In Vitro and In Vivo

por Cecil, Jessica D., O’Brien-Simpson, Neil M., Lenzo, Jason C., Holden, James A., Singleton, William, Perez-Gonzalez, Alexis, Mansell, Ashley, Reynolds, Eric C.
Publicado 2017

Enhanced Antibacterial Activity of Se Nanoparticles Upon Coating with Recombinant Spider Silk Protein eADF4(κ16)

por Huang, Tao, Kumari, Sushma, Herold, Heike, Bargel, Hendrik, Aigner, Tamara B, Heath, Daniel E, O’Brien-Simpson, Neil M, O’Connor, Andrea J, Scheibel, Thomas
Publicado 2020

Differential Responses of Pattern Recognition Receptors to Outer Membrane Vesicles of Three Periodontal Pathogens

por Cecil, Jessica D., O’Brien-Simpson, Neil M., Lenzo, Jason C., Holden, James A., Chen, Yu-Yen, Singleton, William, Gause, Katelyn T., Yan, Yan, Caruso, Frank, Reynolds, Eric C.
Publicado 2016

Chronic oral application of a periodontal pathogen results in brain inflammation, neurodegeneration and amyloid beta production in wild type mice

por Ilievski, Vladimir, Zuchowska, Paulina K., Green, Stefan J., Toth, Peter T., Ragozzino, Michael E., Le, Khuong, Aljewari, Haider W., O’Brien-Simpson, Neil M., Reynolds, Eric C., Watanabe, Keiko
Publicado 2018

Enhancing proline-rich antimicrobial peptide action by homodimerization: influence of bifunctional linker

por Li, Wenyi, Lin, Feng, Hung, Andrew, Barlow, Anders, Sani, Marc-Antoine, Paolini, Rita, Singleton, William, Holden, James, Hossain, Mohammed Akhter, Separovic, Frances, O'Brien-Simpson, Neil M., Wade, John D.
Publicado 2022

Staphylococcus aureus membrane vesicles contain immunostimulatory DNA, RNA and peptidoglycan that activate innate immune receptors and induce autophagy

por Bitto, Natalie J., Cheng, Lesley, Johnston, Ella L., Pathirana, Rishi, Phan, Thanh Kha, Poon, Ivan K. H., O'Brien‐Simpson, Neil M., Hill, Andrew F., Stinear, Timothy P., Kaparakis‐Liaskos, Maria
Publicado 2021

Metabolic Remodeling, Inflammasome Activation, and Pyroptosis in Macrophages Stimulated by Porphyromonas gingivalis and Its Outer Membrane Vesicles

por Fleetwood, Andrew J., Lee, Man K.S., Singleton, William, Achuthan, Adrian, Lee, Ming-Chin, O'Brien-Simpson, Neil M., Cook, Andrew D., Murphy, Andrew J., Dashper, Stuart G., Reynolds, Eric C., Hamilton, John A.
Publicado 2017

Identification of a periodontal pathogen and bihormonal cells in pancreatic islets of humans and a mouse model of periodontitis

por Ilievski, Vladimir, Toth, Peter T., Valyi-Nagy, Klara, Valyi-Nagy, Tibor, Green, Stefan J., Marattil, Rosann S., Aljewari, Haider W., Wicksteed, Barton, O’Brien-Simpson, Neil M., Reynolds, Eric C., Layden, Brian T., Unterman, Terry G., Watanabe, Keiko
Publicado 2020

A therapeutic Porphyromonas gingivalis gingipain vaccine induces neutralising IgG1 antibodies that protect against experimental periodontitis

por O’Brien-Simpson, Neil M, Holden, James A, Lenzo, Jason C, Tan, Yan, Brammar, Gail C, Walsh, Katrina A, Singleton, William, Orth, Rebecca K H, Slakeski, Nada, Cross, Keith J, Darby, Ivan B, Becher, Dorit, Rowe, Tony, Morelli, Adriana Baz, Hammet, Andrew, Nash, Andrew, Brown, Anna, Ma, Bing, Vingadassalom, Didier, McCluskey, Jacqueline, Kleanthous, Harold, Reynolds, Eric C
Publicado 2016