Novel Therapeutic Targets in Depression and Anxiety: Antioxidants as a Candidate Treatment

por Xu, Ying, Wang, Chuang, Klabnik, Jonathan J, O’Donnell, James M
Publicado 2014

Comparison of the Pharmacological Profiles of Selective PDE4B and PDE4D Inhibitors in the Central Nervous System

por Zhang, Chong, Xu, Ying, Zhang, Han-Ting, Gurney, Mark E., O’Donnell, James M.
Publicado 2017

General practitioners' attitudes and preparedness towards Clinical Decision Support in e-Prescribing (CDS-eP) adoption in the West of Ireland: a cross sectional study

por Hor, Chee Peng, O'Donnell, James M, Murphy, Andrew W, O'Brien, Timothy, Kropmans, Thomas JB
Publicado 2010

Antidepressant- and anxiolytic-like effects of the phosphodiesterase-4 (PDE4) inhibitor rolipram on behavior depend on cyclic AMP-response element binding protein (CREB)-mediated n...

por Li, Yun-Feng, Huang, Ying, Amsdell, Simon L., Xiao, Lan, O'Donnell, James M., Zhang, Han-Ting
Publicado 2009

Protection from Amyloid β Peptide–Induced Memory, Biochemical, and Morphological Deficits by a Phosphodiesterase-4D Allosteric Inhibitor

por Cui, Su-Ying, Yang, Ming-Xin, Zhang, Yong-He, Zheng, Victor, Zhang, Han-Ting, Gurney, Mark E., Xu, Ying, O’Donnell, James M.
Publicado 2019

A Novel PDE4D Inhibitor BPN14770 Reverses Scopolamine-Induced Cognitive Deficits via cAMP/SIRT1/Akt/Bcl-2 Pathway

por Wang, Yulu, Gao, Shichao, Zheng, Victor, Chen, Ling, Ma, Min, Shen, Shichen, Qu, Jun, Zhang, Hanting, Gurney, Mark E., O’Donnell, James M., Xu, Ying
Publicado 2020

Memory enhancing effects of BPN14770, an allosteric inhibitor of phosphodiesterase-4D, in wild-type and humanized mice

por Zhang, Chong, Xu, Ying, Chowdhary, Anirudh, Fox, David, Gurney, Mark E., Zhang, Han-Ting, Auerbach, Benjamin D., Salvi, Richard J., Yang, Mingxin, Li, Gaowen, O’Donnell, James M.
Publicado 2018

The effect of resveratrol on beta amyloid-induced memory impairment involves inhibition of phosphodiesterase-4 related signaling

por Wang, Gang, Chen, Ling, Pan, Xiaoyu, Chen, Jiechun, Wang, Liqun, Wang, Weijie, Cheng, Ruochuan, Wu, Fan, Feng, Xiaoqing, Yu, Yingcong, Zhang, Han-Ting, O'Donnell, James M., Xu, Ying
Publicado 2016

METTL3-dependent RNA m(6)A dysregulation contributes to neurodegeneration in Alzheimer’s disease through aberrant cell cycle events

por Zhao, Fanpeng, Xu, Ying, Gao, Shichao, Qin, Lixia, Austria, Quillan, Siedlak, Sandra L., Pajdzik, Kinga, Dai, Qing, He, Chuan, Wang, Wenzhang, O’Donnell, James M., Tang, Beisha, Zhu, Xiongwei
Publicado 2021

Phosphodiesterase-4D Knock-down in the Prefrontal Cortex Alleviates Chronic Unpredictable Stress-Induced Depressive-Like Behaviors and Memory Deficits in Mice

por Wang, Zhen-Zhen, Yang, Wei-Xing, Zhang, Yi, Zhao, Nan, Zhang, You-Zhi, Liu, Yan-Qin, Xu, Ying, Wilson, Steven P., O'Donnell, James M., Zhang, Han-Ting, Li, Yun-Feng
Publicado 2015