Many Roads to Motor Deficits: Loss of Dopamine Signaling in Direct or Indirect Basal Ganglia Pathway Leads to Akinesia through Distinct Physiological Mechanisms

por Calhoon, Gwendolyn G., O'Donnell, Patricio
Publicado 2010

Speaker 3: Patricio O’Donnell, USA

por O’Donnell, Patricio, Cabungcal, Jan, Do, Kim Q.
Publicado 2016

The Nucleus Accumbens: A Switchboard for Goal-Directed Behaviors

por Gruber, Aaron J., Hussain, Rifat J., O'Donnell, Patricio
Publicado 2009

Time-dependent decreases in nucleus accumbens AMPA/NMDA ratio and incubation of sucrose craving in adolescent and adult rats

por Counotte, Danielle S., Schiefer, Christopher, Shaham, Yavin, O’Donnell, Patricio
Publicado 2013

Erratum to: Time-dependent decreases in nucleus accumbens AMPA/NMDA ratio and incubation of sucrose craving in adolescent and adult rats

por Counotte, Danielle S., Schiefer, Christopher, Shaham, Yavin, O’Donnell, Patricio
Publicado 2013

Olanzapine Treatment of Adolescent Rats Alters Adult D2 Modulation of Cortical Inputs to the Ventral Striatum

por Brooks, Julie M., O’Donnell, Patricio, Frost, Douglas O.
Publicado 2016

Effects of NMDA and GABA-A Receptor Antagonism on Auditory Steady-State Synchronization in Awake Behaving Rats

por Sullivan, Elyse M., Timi, Patricia, Hong, L. Elliot, O’Donnell, Patricio
Publicado 2015

Strategies to Address Challenges in Neuroscience Drug Discovery and Development

por O’Donnell, Patricio, Rosen, Laura, Alexander, Robert, Murthy, Venkatesha, Davies, Ceri H, Ratti, Emiliangelo
Publicado 2019

Sign and goal tracker rats process differently the incentive salience of a conditioned stimulus

por Serrano-Barroso, Almudena, Vargas, Juan Pedro, Diaz, Estrella, O’Donnell, Patricio, López, Juan Carlos
Publicado 2019

Expectancy-related changes in firing of dopamine neurons depend on orbitofrontal cortex

por Takahashi, Yuji K., Roesch, Matthew R., Wilson, Robert C., Toreson, Kathy, O’Donnell, Patricio, Niv, Yael, Schoenbaum, Geoffrey
Publicado 2011

Central nervous system effects of TAK-653, an investigational alpha-amino-3-hydroxy-5-methyl-4-isoxazole receptor (AMPAR) positive allosteric modulator in healthy volunteers

por Dijkstra, Francis, O’Donnell, Patricio, Klaassen, Erica, Buhl, Derek, Asgharnejad, Mahnaz, Rosen, Laura, Zuiker, Rob, van Gerven, Joop, Jacobs, Gabriël
Publicado 2022

Electrical impedance myography detects dystrophin-related muscle changes in mdx mice

por Hiyoshi, Tetsuaki, Zhao, Fuqiang, Baba, Rina, Hirakawa, Takeshi, Kuboki, Ryosuke, Suzuki, Kazunori, Tomimatsu, Yoshiro, O’Donnell, Patricio, Han, Steve, Zach, Neta, Nakashima, Masato
Publicado 2023

Assessment of brain cholesterol metabolism biomarker 24S-hydroxycholesterol in schizophrenia

por Chiappelli, Joshua, Quinton, Maria S., Volfson, Dmitri, Cwik, Michael, Marshall, Wyatt, Bruce, Heather, Goldwaser, Eric, Kvarta, Mark, Summerfelt, Ann, Kochunov, Peter, O’Donnell, Patricio, Hong, Liyi Elliot
Publicado 2020

Schizophrenia-associated SLC39A8 polymorphism is a loss-of-function allele altering glutamate receptor and innate immune signaling

por Tseng, Wei Chou, Reinhart, Veronica, Lanz, Thomas A., Weber, Mark L., Pang, Jincheng, Le, Kevin Xuong Vinh, Bell, Robert D., O’Donnell, Patricio, Buhl, Derek L.
Publicado 2021

Hyperactivity and Hypermotivation Associated With Increased Striatal mGluR1 Signaling in a Shank2 Rat Model of Autism

por Modi, Meera E., Brooks, Julie M., Guilmette, Edward R., Beyna, Mercedes, Graf, Radka, Reim, Dominik, Schmeisser, Michael J., Boeckers, Tobias M., O’Donnell, Patricio, Buhl, Derek L.
Publicado 2018

GluN2D-mediated excitatory drive onto medial prefrontal cortical PV+ fast-spiking inhibitory interneurons

por Garst-Orozco, Jonathan, Malik, Ruchi, Lanz, Thomas A., Weber, Mark L., Xi, Hualin, Arion, Dominique, Enwright, John F., Lewis, David A., O’Donnell, Patricio, Sohal, Vikaas S., Buhl, Derek L.
Publicado 2020

The D-amino acid oxidase inhibitor luvadaxistat improves mismatch negativity in patients with schizophrenia in a randomized trial

por O’Donnell, Patricio, Dong, Cheng, Murthy, Venkatesha, Asgharnejad, Mahnaz, Du, Xiaoming, Summerfelt, Ann, Lu, Hong, Xu, Lin, Wendland, Jens R., Dunayevich, Eduardo, Buhl, Derek L., Litman, Robert, Hetrick, William P., Hong, L. Elliot, Rosen, Laura B.
Publicado 2023

3.2 PARVALBUMIN INTERNEURON IMPAIRMENT INDUCED BY OXIDATIVE STRESS AS A COMMON PATHOLOGICAL MECHANISM IN ANIMAL MODELS OF SCHIZOPHRENIA

por Cabungcal, Jan Harry, Steullet, Pascal, Coyle, Joseph, Didriksen, Michael, Gill, Kathryn, Grace, Anthony, Takao, Hensch, LaMantia, Anthony, Lindemann, Lothar, Maynard, Thomas, Meyer, Urs, Morishita, Hirofumi, O’Donnell, Patricio, Puhl, Matthew, Cuenod, Michel, Do, Kim Q
Publicado 2018

Role for neonatal D-serine signaling: prevention of physiological and behavioral deficits in adult Pick1 knockout mice

por Nomura, Jun, Jaaro-Peled, Hanna, Lewis, Eastman, Nuñez-Abades, Pedro, Huppe-Gourgues, Frederic, Cash-Padgett, Tyler, Emiliani, Francesco, Kondo, Mari A., Furuya, Asako, Landek-Salgado, Melissa A., Ayhan, Yavuz, Kamiya, Atsushi, Takumi, Toru, Huganir, Richard, Pletnikov, Mikhail, O’Donnell, Patricio, Sawa, Akira
Publicado 2015

Transcriptome-wide association study reveals two genes that influence mismatch negativity

por Bhat, Anjali, Irizar, Haritz, Thygesen, Johan Hilge, Kuchenbaecker, Karoline, Pain, Oliver, Adams, Rick A., Zartaloudi, Eirini, Harju-Seppänen, Jasmine, Austin-Zimmerman, Isabelle, Wang, Baihan, Muir, Rebecca, Summerfelt, Ann, Du, Xiaoming Michael, Bruce, Heather, O’Donnell, Patricio, Srivastava, Deepak P., Friston, Karl, Hong, L. Elliot, Hall, Mei-Hua, Bramon, Elvira
Publicado 2021