Pre-Ribosomal RNA Processing in Human Cells: From Mechanisms to Congenital Diseases

por Aubert, Maxime, O’Donohue, Marie-Françoise, Lebaron, Simon, Gleizes, Pierre-Emmanuel
Publicado 2018

Functional dichotomy of ribosomal proteins during the synthesis of mammalian 40S ribosomal subunits

por O’Donohue, Marie-Françoise, Choesmel, Valérie, Faubladier, Marlène, Fichant, Gwennaële, Gleizes, Pierre-Emmanuel
Publicado 2010

Analysis of two human pre-ribosomal factors, bystin and hTsr1, highlights differences in evolution of ribosome biogenesis between yeast and mammals

por Carron, Coralie, O’Donohue, Marie-Françoise, Choesmel, Valérie, Faubladier, Marlène, Gleizes, Pierre-Emmanuel
Publicado 2011

An overview of pre-ribosomal RNA processing in eukaryotes

por Henras, Anthony K, Plisson-Chastang, Célia, O'Donohue, Marie-Françoise, Chakraborty, Anirban, Gleizes, Pierre-Emmanuel
Publicado 2015

Structure of a human pre-40S particle points to a role for RACK1 in the final steps of 18S rRNA processing

por Larburu, Natacha, Montellese, Christian, O'Donohue, Marie-Françoise, Kutay, Ulrike, Gleizes, Pierre-Emmanuel, Plisson-Chastang, Célia
Publicado 2016

Distinct cytoplasmic maturation steps of 40S ribosomal subunit precursors require hRio2

por Zemp, Ivo, Wild, Thomas, O'Donohue, Marie-Françoise, Wandrey, Franziska, Widmann, Barbara, Gleizes, Pierre-Emmanuel, Kutay, Ulrike
Publicado 2009

Poly(A)-specific ribonuclease is a nuclear ribosome biogenesis factor involved in human 18S rRNA maturation

por Montellese, Christian, Montel-Lehry, Nathalie, Henras, Anthony K., Kutay, Ulrike, Gleizes, Pierre-Emmanuel, O’Donohue, Marie-Françoise
Publicado 2017

Gradual processing of the ITS1 from the nucleolus to the cytoplasm during synthesis of the human 18S rRNA

por Preti, Milena, O'Donohue, Marie-Françoise, Montel-Lehry, Nathalie, Bortolin-Cavaillé, Marie-Line, Choesmel, Valérie, Gleizes, Pierre-Emmanuel
Publicado 2013

Overexpression of Bcl-2 is associated with apoptotic resistance to the G-quadruplex ligand 12459 but is not sufficient to confer resistance to long-term senescence

por Douarre, Céline, Gomez, Dennis, Morjani, Hamid, Zahm, Jean-Marie, O'Donohue, Marie-Françoise, Eddabra, Lahcen, Mailliet, Patrick, Riou, Jean-François, Trentesaux, Chantal
Publicado 2005

Nucleolar sub-compartments in motion during rRNA synthesis inhibition: Contraction of nucleolar condensed chromatin and gathering of fibrillar centers are concomitant

por Tchelidze, Pavel, Benassarou, Aassif, Kaplan, Hervé, O’Donohue, Marie-Françoise, Lucas, Laurent, Terryn, Christine, Rusishvili, Levan, Mosidze, Giorgi, Lalun, Nathalie, Ploton, Dominique
Publicado 2017

The final step of 40S ribosomal subunit maturation is controlled by a dual key lock

por Plassart, Laura, Shayan, Ramtin, Montellese, Christian, Rinaldi, Dana, Larburu, Natacha, Pichereaux, Carole, Froment, Carine, Lebaron, Simon, O'Donohue, Marie-Françoise, Kutay, Ulrike, Marcoux, Julien, Gleizes, Pierre-Emmanuel, Plisson-Chastang, Celia
Publicado 2021

RNA helicase, DDX27 regulates skeletal muscle growth and regeneration by modulation of translational processes

por Bennett, Alexis H., O’Donohue, Marie-Francoise, Gundry, Stacey R., Chan, Aye T., Widrick, Jeffrey, Draper, Isabelle, Chakraborty, Anirban, Zhou, Yi, Zon, Leonard I., Gleizes, Pierre-Emmanuel, Beggs, Alan H., Gupta, Vandana A.
Publicado 2018

Germline Mutation of RPS20, Encoding a Ribosomal Protein, Causes Predisposition to Hereditary Nonpolyposis Colorectal Carcinoma Without DNA Mismatch Repair Deficiency

por Nieminen, Taina T., O’Donohue, Marie-Françoise, Wu, Yunpeng, Lohi, Hannes, Scherer, Stephen W., Paterson, Andrew D., Ellonen, Pekka, Abdel-Rahman, Wael M., Valo, Satu, Mecklin, Jukka-Pekka, Järvinen, Heikki J., Gleizes, Pierre-Emmanuel, Peltomäki, Päivi
Publicado 2014

Impaired telomere integrity and rRNA biogenesis in PARN‐deficient patients and knock‐out models

por Benyelles, Maname, Episkopou, Harikleia, O'Donohue, Marie‐Françoise, Kermasson, Laëtitia, Frange, Pierre, Poulain, Florian, Burcu Belen, Fatma, Polat, Meltem, Bole‐Feysot, Christine, Langa‐Vives, Francina, Gleizes, Pierre‐Emmanuel, de Villartay, Jean‐Pierre, Callebaut, Isabelle, Decottignies, Anabelle, Revy, Patrick
Publicado 2019

The human methyltransferase ZCCHC4 catalyses N(6)-methyladenosine modification of 28S ribosomal RNA

por Pinto, Rita, Vågbø, Cathrine B, Jakobsson, Magnus E, Kim, Yeji, Baltissen, Marijke P, O’Donohue, Marie-Françoise, Guzmán, Ulises H, Małecki, Jędrzej M, Wu, Jie, Kirpekar, Finn, Olsen, Jesper V, Gleizes, Pierre-Emmanuel, Vermeulen, Michiel, Leidel, Sebastian A, Slupphaug, Geir, Falnes, Pål Ø
Publicado 2020

Mammalian Hbs1L deficiency causes congenital anomalies and developmental delay associated with Pelota depletion and 80S monosome accumulation

por O’Connell, Amy E., Gerashchenko, Maxim V., O’Donohue, Marie-Francoise, Rosen, Samantha M., Huntzinger, Eric, Gleeson, Diane, Galli, Antonella, Ryder, Edward, Cao, Siqi, Murphy, Quinn, Kazerounian, Shideh, Morton, Sarah U., Schmitz-Abe, Klaus, Gladyshev, Vadim N., Gleizes, Pierre-Emmanuel, Séraphin, Bertrand, Agrawal, Pankaj B.
Publicado 2019

Recurring mutations in RPL15 are linked to hydrops fetalis and treatment independence in Diamond-Blackfan anemia

por Wlodarski, Marcin W., Da Costa, Lydie, O’Donohue, Marie-Françoise, Gastou, Marc, Karboul, Narjesse, Montel-Lehry, Nathalie, Hainmann, Ina, Danda, Dominika, Szvetnik, Amina, Pastor, Victor, Paolini, Nahuel, di Summa, Franca M., Tamary, Hannah, Quider, Abed Abu, Aspesi, Anna, Houtkooper, Riekelt H., Leblanc, Thierry, Niemeyer, Charlotte M., Gleizes, Pierre-Emmanuel, MacInnes, Alyson W.
Publicado 2018

HEATR3 variants impair nuclear import of uL18 (RPL5) and drive Diamond-Blackfan anemia

por O’Donohue, Marie-Françoise, Da Costa, Lydie, Lezzerini, Marco, Unal, Sule, Joret, Clément, Bartels, Marije, Brilstra, Eva, Scheijde-Vermeulen, Marijn, Wacheul, Ludivine, De Keersmaecker, Kim, Vereecke, Stijn, Labarque, Veerle, Saby, Manon, Lefevre, Sophie D., Platon, Jessica, Montel-Lehry, Nathalie, Laugero, Nathalie, Lacazette, Eric, van Gassen, Koen, Houtkooper, Riekelt H., Simsek-Kiper, Pelin Ozlem, Leblanc, Thierry, Yarali, Nese, Cetinkaya, Arda, Akarsu, Nurten A., Gleizes, Pierre-Emmanuel, Lafontaine, Denis L. J., MacInnes, Alyson W.
Publicado 2022

Ribosomal protein gene RPL9 variants can differentially impair ribosome function and cellular metabolism

por Lezzerini, Marco, Penzo, Marianna, O’Donohue, Marie-Françoise, Marques dos Santos Vieira, Carolina, Saby, Manon, Elfrink, Hyung L, Diets, Illja J, Hesse, Anne-Marie, Couté, Yohann, Gastou, Marc, Nin-Velez, Alexandra, Nikkels, Peter G J, Olson, Alexandra N, Zonneveld-Huijssoon, Evelien, Jongmans, Marjolijn C J, Zhang, GuangJun, van Weeghel, Michel, Houtkooper, Riekelt H, Wlodarski, Marcin W, Kuiper, Roland P, Bierings, Marc B, van der Werff ten Bosch, Jutte, Leblanc, Thierry, Montanaro, Lorenzo, Dinman, Jonathan D, Da Costa, Lydie, Gleizes, Pierre-Emmanuel, MacInnes, Alyson W
Publicado 2020