Understanding the Role of Mesenchymal Stromal Cells in Treating COVID-19 Acute Respiratory Distress Syndrome

por O’Kane, Cecilia M., Matthay, Michael A.
Publicado 2022

Precision‐cut lung slices: A powerful ex vivo model to investigate respiratory infectious diseases

por Viana, Flávia, O’Kane, Cecilia M., Schroeder, Gunnar N.
Publicado 2021

Hypercapnic acidosis induces mitochondrial dysfunction and impairs the ability of mesenchymal stem cells to promote distal lung epithelial repair

por Fergie, Nicola, Todd, Naomi, McClements, Lana, McAuley, Danny, O’Kane, Cecilia, Krasnodembskaya, Anna
Publicado 2019

Simvastatin decreases the level of heparin-binding protein in patients with acute lung injury

por McAuley, Daniel F, O’Kane, Cecilia M, Craig, Thelma R, Shyamsundar, Murali, Herwald, Heiko, Dib, Karim
Publicado 2013

Heterogeneity of treatment effect by baseline risk of mortality in critically ill patients: re-analysis of three recent sepsis and ARDS randomised controlled trials

por Santhakumaran, Shalini, Gordon, Anthony, Prevost, A. Toby, O’Kane, Cecilia, McAuley, Daniel F., Shankar-Hari, Manu
Publicado 2019

Prevention of post-operative complications by using a HMG-CoA reductase inhibitor in patients undergoing one-lung ventilation for non-cardiac surgery: study protocol for a randomis...

por Shyamsundar, Murali, O’Kane, Cecilia, Perkins, Gavin D., Kennedy, Gavin, Campbell, Christina, Agus, Ashley, Phair, Glenn, McAuley, Danny
Publicado 2018

Keratinocyte growth factor in acute lung injury to reduce pulmonary dysfunction – a randomised placebo-controlled trial (KARE): study protocol

por Cross, Laurence JM, O’Kane, Cecilia M, McDowell, Cliona, Elborn, Jospeh J, Matthay, Michael A, McAuley, Daniel F
Publicado 2013

A randomized clinical trial of ascorbic acid in open abdominal aortic aneurysm repair

por Duffy, Martin J, O’Kane, Cecilia M, Stevenson, Michael, Young, Ian S, Harkin, Denis W, Mullan, Brian A, McAuley, Daniel F
Publicado 2015

Erratum to: Keratinocyte growth factor in acute lung injury to reduce pulmonary dysfunction – a randomised placebo-controlled trial (KARE): study protocol

por Cross, Laurence J. M., O’Kane, Cecilia M., McDowell, Cliona, Elborn, Jospeh J., Matthay, Michael A., McAuley, Daniel F.
Publicado 2017

A Porcine Ex Vivo Lung Perfusion Model To Investigate Bacterial Pathogenesis

por Dumigan, Amy, Fitzgerald, Marianne, Santos, Joana Sá-Pessoa Graca, Hamid, Umar, O’Kane, Cecilia M., McAuley, Danny F., Bengoechea, Jose A.
Publicado 2019

Mesenchymal stromal cell extracellular vesicles rescue mitochondrial dysfunction and improve barrier integrity in clinically relevant models of ARDS

por Dutra Silva, Johnatas, Su, Yue, Calfee, Carolyn S., Delucchi, Kevin L., Weiss, Daniel, McAuley, Danny F., O'Kane, Cecilia, Krasnodembskaya, Anna D.
Publicado 2021

Baseline plasma IL-18 may predict simvastatin treatment response in patients with ARDS: a secondary analysis of the HARP-2 randomised clinical trial

por Boyle, Andrew James, Ferris, Peter, Bradbury, Ian, Conlon, John, Shankar-Hari, Manu, Rogers, Angela J., O’Kane, Cecilia M., McAuley, Daniel F.
Publicado 2022

The relationship between plasma cystatin C, mortality and acute respiratory distress syndrome subphenotype in the HARP-2 trial

por McKelvey, Michael C., Bradbury, Ian, McDowell, Cliona, Calfee, Carolyn S., Weldon, Sinead, O'Kane, Cecilia M., McAuley, Daniel F., Taggart, Clifford C.
Publicado 2023

Hydroxymethylglutaryl-CoA reductase inhibition with simvastatin in Acute lung injury to Reduce Pulmonary dysfunction (HARP-2) trial: study protocol for a randomized controlled tria...

por McAuley, Daniel F, Laffey, John G, O’Kane, Cecilia M, Cross, Mark, Perkins, Gavin D, Murphy, Lynn, McNally, Christine, Crealey, Grainne, Stevenson, Michael
Publicado 2012

Mitochondrial Transfer via Tunneling Nanotubes is an Important Mechanism by Which Mesenchymal Stem Cells Enhance Macrophage Phagocytosis in the In Vitro and In Vivo Models of ARDS

por Jackson, Megan V., Morrison, Thomas J., Doherty, Declan F., McAuley, Daniel F., Matthay, Michael A., Kissenpfennig, Adrien, O'Kane, Cecilia M., Krasnodembskaya, Anna D.
Publicado 2016

Hyperoxaemia and hypoxaemia are associated with harm in patients with ARDS

por Boyle, Andrew J., Holmes, David N., Hackett, Jonathan, Gilliland, Susanna, McCloskey, Michael, O’Kane, Cecilia M., Young, Paul, Di Gangi, Stefania, McAuley, Daniel F.
Publicado 2021

Identifying associations between diabetes and acute respiratory distress syndrome in patients with acute hypoxemic respiratory failure: an analysis of the LUNG SAFE database

por Boyle, Andrew J., Madotto, Fabiana, Laffey, John G., Bellani, Giacomo, Pham, Tài, Pesenti, Antonio, Thompson, B. Taylor, O’Kane, Cecilia M., Deane, Adam M., McAuley, Daniel F.
Publicado 2018

Effect of total cholesterol and statin therapy on mortality in ARDS patients: a secondary analysis of the SAILS and HARP-2 trials

por Pienkos, Shaun M., Moore, Andrew R., Guan, Jiazhen, Levitt, Joseph E., Matthay, Michael A., Baron, Rebecca M., Conlon, John, McAuley, Daniel F., O’Kane, Cecilia M., Rogers, Angela J.
Publicado 2023

Mesenchymal stromal cells-derived extracellular vesicles reprogramme macrophages in ARDS models through the miR-181a-5p-PTEN-pSTAT5-SOCS1 axis

por Su, Yue, Silva, Johnatas Dutra, Doherty, Declan, Simpson, David A, Weiss, Daniel J, Rolandsson-Enes, Sara, McAuley, Daniel F, O'Kane, Cecilia M, Brazil, Derek P, Krasnodembskaya, Anna D
Publicado 2023

Emerging pharmacological therapies for ARDS: COVID-19 and beyond

por Horie, Shahd, McNicholas, Bairbre, Rezoagli, Emanuele, Pham, Tài, Curley, Ger, McAuley, Danny, O’Kane, Cecilia, Nichol, Alistair, dos Santos, Claudia, Rocco, Patricia R. M., Bellani, Giacomo, Laffey, John G.
Publicado 2020