Determinants of gemcitabine response in pancreatic cancer: are we there?

por Fitzpatrick, Orla M., O’Kane, Grainne M.
Publicado 2023

Advances in the management of pancreatic ductal adenocarcinoma

por O’Kane, Grainne M., Ladak, Farah, Gallinger, Steven
Publicado 2021

Avancées dans la prise en charge de l’adénocarcinome canalaire pancréatique

por O’Kane, Grainne M., Ladak, Farah, Gallinger, Steven
Publicado 2021

Third-Generation Tyrosine Kinase Inhibitors Targeting Epidermal Growth Factor Receptor Mutations in Non-Small Cell Lung Cancer

por Barnes, Tristan A., O’Kane, Grainne M., Vincent, Mark David, Leighl, Natasha B.
Publicado 2017

The value of GATA6 immunohistochemistry and computer-assisted diagnosis to predict clinical outcome in advanced pancreatic cancer

por Duan, Kai, Jang, Gun-Ho, Grant, Robert C., Wilson, Julie M., Notta, Faiyaz, O’Kane, Grainne M., Knox, Jennifer J., Gallinger, Steven, Fischer, Sandra
Publicado 2021

Whole-genome sequencing of 20 cholangiocarcinoma cases reveals unique profiles in patients with cirrhosis and primary sclerosing cholangitis

por Holzapfel, Nicholas, Zhang, Amy, Choi, Woo-Jin, Denroche, Robert, Jang, Gunho, Dodd, Anna, Bucur, Roxana, Wilson, Julie, Sapisochin, Gonzalo, Notta, Faiyaz, Grant, Robert C., Gallinger, Steven, Knox, Jennifer J., O’Kane, Grainne M.
Publicado 2023

Clinically impactful metabolic subtypes of pancreatic ductal adenocarcinoma (PDAC)

por Pervin, Jannat, Asad, Mohammad, Cao, Shaolong, Jang, Gun Ho, Feizi, Nikta, Haibe-Kains, Benjamin, Karasinska, Joanna M., O’Kane, Grainne M., Gallinger, Steven, Schaeffer, David F., Renouf, Daniel J., Zogopoulos, George, Bathe, Oliver F.
Publicado 2023

A phase 2 trial of sunitinib in patients with progressive paraganglioma or pheochromocytoma: the SNIPP trial

por O’Kane, Grainne M, Ezzat, Shereen, Joshua, Anthony M., Bourdeau, Isabelle, Leibowitz-Amit, Raya, Olney, Harold J., Krzyzanowska, Monika, Reuther, Dean, Chin, Soo, Wang, Lisa, Brooks, Kelly, Hansen, Aaron R., Asa, Sylvia L., Knox, Jennifer J.
Publicado 2019

Development and evaluation of screening dysphagia tools for observational studies and routine care in cancer patients

por Borean, Michael, Shani, Kishan, Brown, M. Catherine, Chen, Judy, Liang, Mindy, Karkada, Joel, Kooner, Simranjit, Doherty, Mark K., O'Kane, Grainne M., Jang, Raymond, Elimova, Elena, Wong, Rebecca K., Darling, Gail E., Xu, Wei, Howell, Doris, Liu, Geoffrey
Publicado 2018

Germline BRCA2 variants in advanced pancreatic acinar cell carcinoma: A case report and review of literature

por Lee, Cha Len, Holter, Spring, Borgida, Ayelet, Dodd, Anna, Ramotar, Stephanie, Grant, Robert, Wasson, Kristy, Elimova, Elena, Jang, Raymond W, Moore, Malcolm, Kim, Tae Kyoung, Khalili, Korosh, Moulton, Carol-Anne, Gallinger, Steven, O’Kane, Grainne M, Knox, Jennifer J
Publicado 2022

Comparison of Four Clinical Prognostic Scores in Patients with Advanced Gastric and Esophageal Cancer

por Ma, Lucy X, Espin-Garcia, Osvaldo, Bach, Yvonne, Aoyama, Hiroko, Allen, Michael J, Wang, Xin, Darling, Gail E, Yeung, Jonathan, Swallow, Carol J, Brar, Savtaj, Veit-Haibach, Patrick, Kalimuthu, Sangeetha, Wong, Rebecca, Chen, Eric X, O’Kane, Grainne M, Jang, Raymond W, Elimova, Elena
Publicado 2022

Chemokine expression predicts T cell-inflammation and improved survival with checkpoint inhibition across solid cancers

por Romero, Joan Miguel, Titmuss, Emma, Wang, Yifan, Vafiadis, James, Pacis, Alain, Jang, Gun Ho, Zhang, Amy, Golesworthy, Bryn, Lenko, Tatiana, Williamson, Laura M., Grünwald, Barbara, O’Kane, Grainne M., Jones, Steven J. M., Marra, Marco. A., Wilson, Julie M., Gallinger, Steven, Laskin, Janessa, Zogopoulos, George
Publicado 2023

Management of primary hepatic malignancies during the COVID-19 pandemic: recommendations for risk mitigation from a multidisciplinary perspective

por Barry, Aisling, Apisarnthanarax, Smith, O'Kane, Grainne M, Sapisochin, Gonzalo, Beecroft, Robert, Salem, Riad, Yoon, Sang Min, Lim, Young-Suk, Bridgewater, John, Davidson, Brian, Scorsetti, Marta, Solbiati, Luigi, Diehl, Adam, Schuffenegger, Pablo Munoz, Sham, Jonathan G, Cavallucci, David, Galvin, Zita, Dawson, Laura A, Hawkins, Maria A
Publicado 2020

Real‐world health utility scores and toxicities to tyrosine kinase inhibitors in epidermal growth factor receptor mutated advanced non‐small cell lung cancer

por Jiang, Shirley Xue, Walton, Ryan N., Hueniken, Katrina, Baek, Justine, McCartney, Alexandra, Labbé, Catherine, Smith, Elliot, Chan, Sze Wah Samuel, Chen, RuiQi, Brown, Catherine, Patel, Devalben, Liang, Mindy, Eng, Lawson, Sacher, Adrian, Bradbury, Penelope, Leighl, Natasha B., Shepherd, Frances A., Xu, Wei, Liu, Geoffrey, Hurry, Manjusha, O'Kane, Grainne M.
Publicado 2019

Screening for mismatch repair deficiency in colorectal cancer: data from three academic medical centers

por O'Kane, Grainne M., Ryan, Éanna, McVeigh, Terri P., Creavin, Ben, Hyland, John MP., O'Donoghue, Diarmuid P., Keegan, Denise, Geraghty, Robert, Flannery, Delia, Nolan, Carmel, Donovan, Emily, Mehigan, Brian J., McCormick, Paul, Muldoon, Cian, Farrell, Michael, Shields, Conor, Mulligan, Niall, Kennedy, Michael John, Green, Andrew J., Winter, Desmond C., MacMathuna, Padraic, Sheahan, Kieran, Gallagher, David J.
Publicado 2017

Intra-Tumoral CD8+ T-Cell Infiltration and PD-L1 Positivity in Homologous Recombination Deficient Pancreatic Ductal Adenocarcinoma

por Golesworthy, Bryn, Wang, Yifan, Tanti, Amanda, Pacis, Alain, Romero, Joan Miguel, Cuggia, Adeline, Domecq, Celine, Bourdel, Guillaume, Denroche, Robert E., Jang, Gun Ho, Grant, Robert C., Borgida, Ayelet, Grünwald, Barbara T., Dodd, Anna, Wilson, Julie M., Bourque, Guillaume, O’Kane, Grainne M., Fischer, Sandra E., Kron, Chelsea Maedler, Fiset, Pierre-Olivier, Omeroglu, Atilla, Foulkes, William D., Gallinger, Steven, Guiot, Marie-Christine, Gao, Zu-Hua, Zogopoulos, George
Publicado 2022

Spectrum of Response to Platinum and PARP Inhibitors in Germline BRCA–Associated Pancreatic Cancer in the Clinical and Preclinical Setting

por Stossel, Chani, Raitses-Gurevich, Maria, Atias, Dikla, Beller, Tamar, Glick Gorman, Yulia, Halperin, Sharon, Peer, Eyal, Denroche, Robert E., Zhang, Amy, Notta, Faiyaz, Wilson, Julie M., O'Kane, Grainne M., Haimov Talmoud, Elina, Amison, Nora, Schvimer, Michael, Salpeter, Seth J., Bar, Vered, Zundelevich, Adi, Tirosh, Itay, Tal, Rotem, Dinstag, Gal, Kinar, Yaron, Eliezer, Yonatan, Ben-David, Uri, Gavert, Nancy S., Straussman, Ravid, Gallinger, Steven J., Berger, Raanan, Golan, Talia
Publicado 2023

Integrative analysis of KRAS wildtype metastatic pancreatic ductal adenocarcinoma reveals mutation and expression-based similarities to cholangiocarcinoma

por Topham, James T., Tsang, Erica S., Karasinska, Joanna M., Metcalfe, Andrew, Ali, Hassan, Kalloger, Steve E., Csizmok, Veronika, Williamson, Laura M., Titmuss, Emma, Nielsen, Karina, Negri, Gian Luca, Spencer Miko, Sandra E., Jang, Gun Ho, Denroche, Robert E., Wong, Hui-li, O’Kane, Grainne M., Moore, Richard A., Mungall, Andrew J., Loree, Jonathan M., Notta, Faiyaz, Wilson, Julie M., Bathe, Oliver F., Tang, Patricia A., Goodwin, Rachel, Morin, Gregg B., Knox, Jennifer J., Gallinger, Steven, Laskin, Janessa, Marra, Marco A., Jones, Steven J. M., Schaeffer, David F., Renouf, Daniel J.
Publicado 2022