DeORFanizing Candida albicans Genes using Coexpression

por O’Meara, Teresa R., O’Meara, Matthew J.
Publicado 2021

Ligand Similarity Complements Sequence, Physical Interaction, and Co-Expression for Gene Function Prediction

por O’Meara, Matthew J., Ballouz, Sara, Shoichet, Brian K., Gillis, Jesse
Publicado 2016

The life and times of endogenous opioid peptides: Updated understanding of synthesis, spatiotemporal dynamics, and the clinical impact in alcohol use disorder

por Margolis, Elyssa B., Moulton, Madelyn G., Lambeth, Philip S., O’Meara, Matthew J.
Publicado 2023

Imaging-based screening identifies modulators of the eIF3 translation initiation factor complex in Candida albicans

por Metzner, Katura, O’Meara, Matthew J, Halligan, Benjamin, Wotring, Jesse W., Sexton, Jonathan Z, O’Meara, Teresa R
Publicado 2023

Reengineering biocatalysts: Computational redesign of chondroitinase ABC improves efficacy and stability

por Hettiaratchi, Marian H., O’Meara, Matthew J., O’Meara, Teresa R., Pickering, Andrew J., Letko-Khait, Nitzan, Shoichet, Molly S.
Publicado 2020

A Web Resource for Standardized Benchmark Datasets, Metrics, and Rosetta Protocols for Macromolecular Modeling and Design

por Ó Conchúir, Shane, Barlow, Kyle A., Pache, Roland A., Ollikainen, Noah, Kundert, Kale, O'Meara, Matthew J., Smith, Colin A., Kortemme, Tanja
Publicado 2015

Multiple ParA/MinD ATPases coordinate the positioning of disparate cargos in a bacterial cell

por Pulianmackal, Lisa T., Limcaoco, Jose Miguel I., Ravi, Keerthikka, Yang, Sinyu, Zhang, Jeffrey, Tran, Mimi K., Ghalmi, Maria, O’Meara, Matthew J., Vecchiarelli, Anthony G.
Publicado 2023

CryptoCEN: A Co-Expression Network for Cryptococcus neoformans reveals novel proteins involved in DNA damage repair

por O’Meara, Matthew J., Rapala, Jackson R., Nichols, Connie B., Alexandre, Christina, Billmyre, R. Blake, Steenwyk, Jacob L, Alspaugh, J. Andrew, O’Meara, Teresa R.
Publicado 2023

Valproic acid-induced changes of 4D nuclear morphology in astrocyte cells

por Kalinin, Alexandr A., Hou, Xinhai, Ade, Alex S., Fon, Gordon-Victor, Meixner, Walter, Higgins, Gerald A., Sexton, Jonathan Z., Wan, Xiang, Dinov, Ivo D., O’Meara, Matthew J., Athey, Brian D.
Publicado 2021

Global proteomic analyses define an environmentally contingent Hsp90 interactome and reveal chaperone-dependent regulation of stress granule proteins and the R2TP complex in a fung...

por O’Meara, Teresa R., O’Meara, Matthew J., Polvi, Elizabeth J., Pourhaghighi, M. Reza, Liston, Sean D., Lin, Zhen-Yuan, Veri, Amanda O., Emili, Andrew, Gingras, Anne-Claude, Cowen, Leah E.
Publicado 2019

In Vitro Evaluation and Mitigation of Niclosamide’s Liabilities as a COVID-19 Treatment

por Wotring, Jesse W., McCarty, Sean M., Shafiq, Khadija, Zhang, Charles J., Nguyen, Theophilus, Meyer, Sophia R., Fursmidt, Reid, Mirabelli, Carmen, Clasby, Martin C., Wobus, Christiane E., O’Meara, Matthew J., Sexton, Jonathan Z.
Publicado 2022

In Vitro Evaluation and Mitigation of Niclosamide’s Liabilities as a COVID-19 Treatment

por Wotring, Jesse W., McCarty, Sean M., Shafiq, Khadija, Zhang, Charles J., Nguyen, Theophilus, Meyer, Sophia R., Fursmidt, Reid, Mirabelli, Carmen, Clasby, Martin C., Wobus, Christiane E., O’Meara, Matthew J., Sexton, Jonathan Z.
Publicado 2022

Ultra-large library docking for discovering new chemotypes

por Lyu, Jiankun, Wang, Sheng, Balius, Trent E., Singh, Isha, Levit, Anat, Moroz, Yurii S., O’Meara, Matthew J., Che, Tao, Algaa, Enkhjargal, Tolmachova, Kateryna, Tolmachev, Andrey A., Shoichet, Brian K., Roth, Bryan L., Irwin, John J.
Publicado 2019

Candida albicans selection for human commensalism results in substantial within-host diversity without decreasing fitness for invasive disease

por Anderson, Faith M., Visser, Noelle D., Amses, Kevin R., Hodgins-Davis, Andrea, Weber, Alexandra M., Metzner, Katura M., McFadden, Michael J., Mills, Ryan E., O’Meara, Matthew J., James, Timothy Y., O’Meara, Teresa R.
Publicado 2023

High-Throughput Screening Identifies Genes Required for Candida albicans Induction of Macrophage Pyroptosis

por O’Meara, Teresa R., Duah, Kwamaa, Guo, Cynthia X., Maxson, Michelle E., Gaudet, Ryan G., Koselny, Kristy, Wellington, Melanie, Powers, Michael E., MacAlpine, Jessie, O’Meara, Matthew J., Veri, Amanda O., Grinstein, Sergio, Noble, Suzanne M., Krysan, Damian, Gray-Owen, Scott D., Cowen, Leah E.
Publicado 2018

Prediction of enzymatic pathways by integrative pathway mapping

por Calhoun, Sara, Korczynska, Magdalena, Wichelecki, Daniel J, San Francisco, Brian, Zhao, Suwen, Rodionov, Dmitry A, Vetting, Matthew W, Al-Obaidi, Nawar F, Lin, Henry, O'Meara, Matthew J, Scott, David A, Morris, John H, Russel, Daniel, Almo, Steven C, Osterman, Andrei L, Gerlt, John A, Jacobson, Matthew P, Shoichet, Brian K, Sali, Andrej
Publicado 2018

Morphological Cell Profiling of SARS-CoV-2 Infection Identifies Drug Repurposing Candidates for COVID-19

por Mirabelli, Carmen, Wotring, Jesse W., Zhang, Charles J., McCarty, Sean M., Fursmidt, Reid, Frum, Tristan, Kadambi, Namrata S., Amin, Anya T., O’Meara, Teresa R., Pretto, Carla D., Spence, Jason R., Huang, Jessie, Alysandratos, Konstantinos D., Kotton, Darrell N., Handelman, Samuel K., Wobus, Christiane E., Weatherwax, Kevin J., Mashour, George A., O’Meara, Matthew J., Sexton, Jonathan Z.
Publicado 2020

Phospholipidosis is a shared mechanism underlying the in vitro antiviral activity of many repurposed drugs against SARS-CoV-2

por Tummino, Tia A., Rezelj, Veronica V., Fischer, Benoit, Fischer, Audrey, O’Meara, Matthew J., Monel, Blandine, Vallet, Thomas, Zhang, Ziyang, Alon, Assaf, O’Donnell, Henry R., Lyu, Jiankun, Schadt, Heiko, White, Kris M, Krogan, Nevan J., Urban, Laszlo, Shokat, Kevan M., Kruse, Andrew C., García-Sastre, Adolfo, Schwartz, Olivier, Moretti, Francesca, Vignuzzi, Marco, Pognan, Francois, Shoichet, Brian K.
Publicado 2021

Leveraging machine learning essentiality predictions and chemogenomic interactions to identify antifungal targets

por Fu, Ci, Zhang, Xiang, Veri, Amanda O., Iyer, Kali R., Lash, Emma, Xue, Alice, Yan, Huijuan, Revie, Nicole M., Wong, Cassandra, Lin, Zhen-Yuan, Polvi, Elizabeth J., Liston, Sean D., VanderSluis, Benjamin, Hou, Jing, Yashiroda, Yoko, Gingras, Anne-Claude, Boone, Charles, O’Meara, Teresa R., O’Meara, Matthew J., Noble, Suzanne, Robbins, Nicole, Myers, Chad L., Cowen, Leah E.
Publicado 2021

Morphological cell profiling of SARS-CoV-2 infection identifies drug repurposing candidates for COVID-19

por Mirabelli, Carmen, Wotring, Jesse W., Zhang, Charles J., McCarty, Sean M., Fursmidt, Reid, Pretto, Carla D., Qiao, Yuanyuan, Zhang, Yuping, Frum, Tristan, Kadambi, Namrata S., Amin, Anya T., O’Meara, Teresa R., Spence, Jason R., Huang, Jessie, Alysandratos, Konstantinos D., Kotton, Darrell N., Handelman, Samuel K., Wobus, Christiane E., Weatherwax, Kevin J., Mashour, George A., O’Meara, Matthew J., Chinnaiyan, Arul M., Sexton, Jonathan Z.
Publicado 2021