Modulation of the BRCA1 Protein and Induction of Apoptosis in Triple Negative Breast Cancer Cell Lines by the Polyphenolic Compound Curcumin

por Rowe, Danica L., Ozbay, Tuba, O’Regan, Ruth M., Nahta, Rita
Publicado 2009

In vitro evaluation of pan-PI3-kinase inhibitor SF1126 in trastuzumab-sensitive and trastuzumab-resistant HER2-over-expressing breast cancer cells

por Ozbay, Tuba, Durden, Donald L., Liu, Tongrui, O’Regan, Ruth M., Nahta, Rita
Publicado 2009

The Efficacy of CB-103, a First-in-Class Transcriptional Notch Inhibitor, in Preclinical Models of Breast Cancer

por Vigolo, Michele, Urech, Charlotte, Lamy, Sebastien, Monticone, Giulia, Zabaleta, Jovanny, Hossain, Fokhrul, Wyczechowska, Dorota, Del Valle, Luis, O’Regan, Ruth M., Miele, Lucio, Lehal, Rajwinder, Majumder, Samarpan
Publicado 2023

Silencing CDK4 radiosensitizes breast cancer cells by promoting apoptosis

por Hagen, Katie R, Zeng, Xiangbin, Lee, Mi-Young, Tucker Kahn, Shannon, Harrison Pitner, Mary Kathryn, Zaky, Sandra S, Liu, Yuan, O’Regan, Ruth M, Deng, Xingming, Saavedra, Harold I
Publicado 2013

A Novel Pathway that Links Caveolin-1 Down-Regulation to BRCA1 Dysfunction in Serous Epithelial Ovarian Cancer Cells

por Xu, Jingyao, Agyemang, Stephanie, Qin, Yunlong, Aysola, Kartik, Giles, Mercedes, Oprea, Gabriela, O’Regan, Ruth M, Partridge, Edward E, Harris-Hooker, Sandra, Rice, Valarie Montgomery, Reddy, E. Shyam P, Rao, Veena N
Publicado 2014

A phase 2 study of everolimus combined with trastuzumab and paclitaxel in patients with HER2-overexpressing advanced breast cancer that progressed during prior trastuzumab and taxa...

por Hurvitz, Sara A., Dalenc, Florence, Campone, Mario, O’Regan, Ruth M., Tjan-Heijnen, Vivianne C., Gligorov, Joseph, Llombart, Antonio, Jhangiani, Haresh, Mirshahidi, Hamid R., Tan-Chiu, Elizabeth, Miao, Sara, El-Hashimy, Mona, Lincy, Jeremie, Taran, Tetiana, Soria, Jean-Charles, Sahmoud, Tarek, André, Fabrice
Publicado 2013

A phase I study of talazoparib (BMN 673) combined with carboplatin and paclitaxel in patients with advanced solid tumors (NCI9782)

por Leal, Ticiana A., Sharifi, Marina N., Chan, Nancy, Wesolowski, Robert, Turk, Anita A., Bruce, Justine Y., O'Regan, Ruth M., Eickhoff, Jens, Barroilhet, Lisa M., Malhotra, Jyoti, Mehnert, Janice, Girda, Eugenia, Wiley, Elizabeth, Schmitz, Natalie, Andrews, Shannon, Liu, Glenn, Wisinski, Kari B.
Publicado 2022

Simultaneous Multi-Organ Metastases from Chemo-Resistant Triple-Negative Breast Cancer Are Prevented by Interfering with WNT-Signaling

por Fatima, Iram, El-Ayachi, Ikbale, Playa, Hilaire C., Alva-Ornelas, Jackelyn A., Khalid, Aysha B., Kuenzinger, William L., Wend, Peter, Pence, Jackelyn C., Brakefield, Lauren, Krutilina, Raisa I., Johnson, Daniel L., O’Regan, Ruth M., Seewaldt, Victoria, Seagroves, Tiffany N., Krum, Susan A., Miranda-Carboni, Gustavo A.
Publicado 2019