Distinct neuroinflammatory signatures exist across genetic and sporadic amyotrophic lateral sclerosis cohorts

por Rifai, Olivia M, O’Shaughnessy, Judi, Dando, Owen R, Munro, Alison F, Sewell, Michael D E, Abrahams, Sharon, Waldron, Fergal M, Sibley, Christopher R, Gregory, Jenna M
Publicado 2023

pTDP‐43 aggregates accumulate in non‐central nervous system tissues prior to symptom onset in amyotrophic lateral sclerosis: a case series linking archival surgical biopsies with c...

por Pattle, Samuel B, O'Shaughnessy, Judi, Kantelberg, Owen, Rifai, Olivia M, Pate, Judith, Nellany, Kristine, Hays, Nadine, Arends, Mark J, Horrocks, Mathew H, Waldron, Fergal M, Gregory, Jenna M
Publicado 2022

Random forest modelling demonstrates microglial and protein misfolding features to be key phenotypic markers in C9orf72‐ALS

por Rifai, Olivia M, Longden, James, O'Shaughnessy, Judi, Sewell, Michael DE, Pate, Judith, McDade, Karina, Daniels, Michael JD, Abrahams, Sharon, Chandran, Siddharthan, McColl, Barry W, Sibley, Christopher R, Gregory, Jenna M
Publicado 2022

Two-color coincidence single-molecule pulldown for the specific detection of disease-associated protein aggregates

por Saleeb, Rebecca S., Leighton, Craig, Lee, Ji-Eun, O’Shaughnessy, Judi, Jeacock, Kiani, Chappard, Alexandre, Cumberland, Robyn, Zhao, Tianxiao, Ball, Sarah R., Sunde, Margaret, Clarke, David J., Piché, Kristin, McPhail, Jacob A., Louwrier, Ariel, Angers, Rachel, Gandhi, Sonia, Downey, Patrick, Kunath, Tilo, Horrocks, Mathew H.
Publicado 2023