Uncovering mechanisms of nuclear degradation in keratinocytes: A paradigm for nuclear degradation in other tissues

por Rogerson, Clare, Bergamaschi, Daniele, O'Shaughnessy, Ryan F. L.
Publicado 2018

Perspective: Controlling Epidermal Terminal Differentiation with Transcriptional Bursting and RNA Bodies

por Wotherspoon, Duncan, Rogerson, Clare, O’Shaughnessy, Ryan F.L.
Publicado 2020

Phosphoinositide 3-Kinase-Dependent Signalling Pathways in Cutaneous Squamous Cell Carcinomas

por Janus, Joanna M., O’Shaughnessy, Ryan F. L., Harwood, Catherine A., Maffucci, Tania
Publicado 2017

CD161(+) Tconv and CD161(+) Treg Share a Transcriptional and Functional Phenotype despite Limited Overlap in TCRβ Repertoire

por Duurland, Chantal L., Brown, Chrysothemis C., O’Shaughnessy, Ryan F. L., Wedderburn, Lucy R.
Publicado 2017

Akt1-associated actomyosin remodelling is required for nuclear lamina dispersal and nuclear shrinkage in epidermal terminal differentiation

por Rogerson, Clare, Wotherspoon, Duncan J., Tommasi, Cristina, Button, Robert W., O’Shaughnessy, Ryan F. L.
Publicado 2021

AKT1 Loss Correlates with Episomal HPV16 in Vulval Intraepithelial Neoplasia

por Ekeowa-Anderson, Arucha L., Purdie, Karin J., Gibbon, Karen, Byrne, Carolyn R., Arbeit, Jeffrey M., Harwood, Catherine A., O'Shaughnessy, Ryan F. L.
Publicado 2012

T-Cell Reconstitution after Thymus Xenotransplantation Induces Hair Depigmentation and Loss

por Furmanski, Anna L, O'Shaughnessy, Ryan F L, Saldana, Jose Ignacio, Blundell, Michael P, Thrasher, Adrian J, Sebire, Neil J, Davies, E Graham, Crompton, Tessa
Publicado 2013

Sonic Hedgehog signaling limits atopic dermatitis via Gli2-driven immune regulation

por Papaioannou, Eleftheria, Yánez, Diana C., Ross, Susan, Lau, Ching-In, Solanki, Anisha, Chawda, Mira Manilal, Virasami, Alex, Ranz, Ismael, Ono, Masahiro, O’Shaughnessy, Ryan F. L., Crompton, Tessa
Publicado 2019

A mechanistic target of rapamycin complex 1/2 (mTORC1)/V-Akt murine thymoma viral oncogene homolog 1 (AKT1)/cathepsin H axis controls filaggrin expression and processing in skin, a...

por Naeem, Aishath S., Tommasi, Cristina, Cole, Christian, Brown, Stuart J., Zhu, Yanan, Way, Benjamin, Willis Owen, Saffron A.G., Moffatt, Miriam, Cookson, William O., Harper, John I., Di, Wei-Li, Brown, Sara J., Reinheckel, Thomas, O'Shaughnessy, Ryan F.L.
Publicado 2017