A yeast FRET biosensor enlightens cAMP signaling

por Botman, Dennis, O’Toole, Tom G., Goedhart, Joachim, Bruggeman, Frank J., van Heerden, Johan H., Teusink, Bas
Publicado 2021

Activation-induced colocalisation of SCAMP5 with IFNα in human plasmacytoid dendritic cells

por Pouw, Juliëtte N, Olde Nordkamp, Michel A M, O'Toole, Tom G, Radstake, Timothy R D J, Leijten, Emmerik F A, Boes, Marianne
Publicado 2022

Fatal attraction in glycolysis: how Saccharomyces cerevisiae manages sudden transitions to high glucose

por Heerden, Johan H. v., Wortel, Meike T., Bruggeman, Frank J., Heijnen, Joseph J., Bollen, Yves J., Planqué, Robert, Hulshof, Josephus, O’Toole, Tom G., Wahl, S. A., Teusink, Bas
Publicado 2014

Disruption of sialic acid metabolism drives tumor growth by augmenting CD8(+) T cell apoptosis

por Cornelissen, Lenneke A.M., Blanas, Athanasios, van der Horst, Joost C., Kruijssen, Laura, Zaal, Anouk, O'Toole, Tom, Wiercx, Lieke, van Kooyk, Yvette, van Vliet, Sandra J.
Publicado 2019

Tn Antigen Expression Contributes to an Immune Suppressive Microenvironment and Drives Tumor Growth in Colorectal Cancer

por Cornelissen, Lenneke A. M., Blanas, Athanasios, Zaal, Anouk, van der Horst, Joost C., Kruijssen, Laura J. W., O’Toole, Tom, van Kooyk, Yvette, van Vliet, Sandra J.
Publicado 2020

A Human Cell Line Model for Interferon-α Driven Dendritic Cell Differentiation

por Ruben, Jurjen M., Visser, Lindy L., Heinhuis, Kimberley M., O’Toole, Tom, Bontkes, Hetty J., Westers, Theresia M., Ossenkoppele, Gert J., de Gruijl, Tanja D., van de Loosdrecht, Arjan A.
Publicado 2015

A Hybrid III stepped wedge cluster randomized trial testing an implementation strategy to facilitate the use of an evidence-based practice in VA Homeless Primary Care Treatment Pro...

por Simmons, Molly M., Gabrielian, Sonya, Byrne, Thomas, McCullough, Megan B., Smith, Jeffery L., Taylor, Thom J., O’Toole, Tom P., Kane, Vincent, Yakovchenko, Vera, McInnes, D. Keith, Smelson, David A.
Publicado 2017

Internalization and presentation of myelin antigens by the brain endothelium guides antigen-specific T cell migration

por Lopes Pinheiro, Melissa A, Kamermans, Alwin, Garcia-Vallejo, Juan J, van het Hof, Bert, Wierts, Laura, O'Toole, Tom, Boeve, Daniël, Verstege, Marleen, van der Pol, Susanne MA, van Kooyk, Yvette, de Vries, Helga E, Unger, Wendy WJ
Publicado 2016

Increased Bone Marrow Uptake and Accumulation of Very-Late Antigen-4 Targeted Lipid Nanoparticles

por Swart, Laura E., Fens, Marcel H. A. M., van Oort, Anita, Waranecki, Piotr, Mata Casimiro, L. Daniel, Tuk, David, Hendriksen, Martijn, van den Brink, Luca, Schweighart, Elizabeth, Seinen, Cor, Nelson, Ryan, Krippner-Heidenreich, Anja, O’Toole, Tom, Schiffelers, Raymond M., Kooijmans, Sander, Heidenreich, Olaf
Publicado 2023

Feasibility of alcohol screening among patients receiving opioid treatment in primary care

por Henihan, Anne Marie, McCombe, Geoff, Klimas, Jan, Swan, Davina, Leahy, Dorothy, Anderson, Rolande, Bury, Gerard, Dunne, Colum P., Keenan, Eamon, Lambert, John S., Meagher, David, O’Gorman, Clodagh, O’Toole, Tom P., Saunders, Jean, Shorter, Gillian W., Smyth, Bobby P., Kaner, Eileen, Cullen, Walter
Publicado 2016

Primary care and youth mental health in Ireland: qualitative study in deprived urban areas

por Leahy, Dorothy, Schaffalitzky, Elisabeth, Armstrong, Claire, Bury, Gerard, Cussen-Murphy, Paula, Davis, Rachel, Dooley, Barbara, Gavin, Blanaid, Keane, Rory, Keenan, Eamon, Latham, Linda, Meagher, David, McGorry, Pat, McNicholas, Fiona, O’Connor, Ray, O’Dea, Ellen, O’Keane, Veronica, O’Toole, Tom P, Reilly, Edel, Ryan, Patrick, Sanci, Lena, Smyth, Bobby P, Cullen, Walter
Publicado 2013

Multifactorial resistance to aminopeptidase inhibitor prodrug CHR2863 in myeloid leukemia cells: down-regulation of carboxylesterase 1, drug sequestration in lipid droplets and pro...

por Verbrugge, Sue Ellen, Al, Marjon, Assaraf, Yehuda G., Kammerer, Sarah, Chandrupatla, Durga M.S.H., Honeywell, Richard, Musters, Rene P.J., Giovannetti, Elisa, O'Toole, Tom, Scheffer, George L., Krige, David, de Gruijl, Tanja D., Niessen, Hans W.M., Lems, Willem F., Kramer, Pieternella A., Scheper, Rik J., Cloos, Jacqueline, Ossenkoppele, Gert J., Peters, Godefridus J., Jansen, Gerrit
Publicado 2015

Selective tumor antigen vaccine delivery to human CD169(+) antigen-presenting cells using ganglioside-liposomes

por Affandi, Alsya J., Grabowska, Joanna, Olesek, Katarzyna, Lopez Venegas, Miguel, Barbaria, Arnaud, Rodríguez, Ernesto, Mulder, Patrick P. G., Pijffers, Helen J., Ambrosini, Martino, Kalay, Hakan, O’Toole, Tom, Zwart, Eline S., Kazemier, Geert, Nazmi, Kamran, Bikker, Floris J., Stöckl, Johannes, van den Eertwegh, Alfons J. M., de Gruijl, Tanja D., Storm, Gert, van Kooyk, Yvette, den Haan, Joke M. M.
Publicado 2020

Analysis of the glyco-code in pancreatic ductal adenocarcinoma identifies glycan-mediated immune regulatory circuits

por Rodriguez, Ernesto, Boelaars, Kelly, Brown, Kari, Madunić, Katarina, van Ee, Thomas, Dijk, Frederike, Verheij, Joanne, Li, R. J. Eveline, Schetters, Sjoerd T. T., Meijer, Laura L., Le Large, Tessa Y. S., Driehuis, Else, Clevers, Hans, Bruijns, Sven C. M., O’Toole, Tom, van Vliet, Sandra J., Bijlsma, Maarten F., Wuhrer, Manfred, Kazemier, Geert, Giovannetti, Elisa, Garcia-Vallejo, Juan J., van Kooyk, Yvette
Publicado 2022

Replication of Plasmodium in reticulocytes can occur without hemozoin formation, resulting in chloroquine resistance

por Lin, Jing-wen, Spaccapelo, Roberta, Schwarzer, Evelin, Sajid, Mohammed, Annoura, Takeshi, Deroost, Katrien, Ravelli, Raimond B.G., Aime, Elena, Capuccini, Barbara, Mommaas-Kienhuis, Anna M., O’Toole, Tom, Prins, Frans, Franke-Fayard, Blandine M.D., Ramesar, Jai, Chevalley-Maurel, Séverine, Kroeze, Hans, Koster, Abraham J., Tanke, Hans J., Crisanti, Andrea, Langhorne, Jean, Arese, Paolo, Van den Steen, Philippe E., Janse, Chris J., Khan, Shahid M.
Publicado 2015

Maternal retinoids control type 3 innate lymphoid cells and set the offspring immunity

por van de Pavert, Serge A., Ferreira, Manuela, Domingues, Rita G., Ribeiro, Hélder, Molenaar, Rosalie, Moreira-Santos, Lara, Almeida, Francisca F., Ibiza, Sales, Barbosa, Inês, Goverse, Gera, Labão-Almeida, Carlos, Godinho-Silva, Cristina, Konijn, Tanja, Schooneman, Dennis, O’Toole, Tom, Mizee, Mark R., Habani, Yasmin, Haak, Esther, Santori, Fabio R., Littman, Dan R., Schulte-Merker, Stefan, Dzierzak, Elaine, Simas, J. Pedro, Mebius, Reina E., Veiga-Fernandes, Henrique
Publicado 2014