Targeting cancer-cell mitochondria and metabolism to improve radiotherapy response

por McCann, Emma, O'Sullivan, Jacintha, Marcone, Simone
Publicado 2020

Prognostic, Diagnostic and Predictive Biomarkers in the Barrett’s Oesophagus-Adenocarcinoma Disease Sequence

por O’Dowd, Darragh, O’Sullivan, Jacintha, Marcone, Simone
Publicado 2022

Tumor conditioned media from colorectal cancer patients inhibits dendritic cell maturation

por Michielsen, Adriana J., O’Sullivan, Jacintha N., Ryan, Elizabeth J.
Publicado 2012

Dendritic cell inhibition correlates with survival of colorectal cancer patients on bevacizumab treatment

por Michielsen, Adriana J., Ryan, Elizabeth J., O’Sullivan, Jacintha N.
Publicado 2012

Can the Efficacy of [(18)F]FDG-PET/CT in Clinical Oncology Be Enhanced by Screening Biomolecular Profiles?

por O’Neill, Hazel, Malik, Vinod, Johnston, Ciaran, Reynolds, John V, O’Sullivan, Jacintha
Publicado 2019

Bioactive indanes: insight into the bioactivity of indane dimers related to the lead anti-inflammatory molecule PH46A

por Chan, Kit, Frankish, Neil, Zhang, Tao, Ece, Abdulilah, Cannon, Aoife, O'Sullivan, Jacintha, Sheridan, Helen
Publicado 2020

Evaluation of Cysteinyl Leukotriene Signaling as a Therapeutic Target for Colorectal Cancer

por Burke, Lorraine, Butler, Clare T., Murphy, Adrian, Moran, Bruce, Gallagher, William M., O'Sullivan, Jacintha, Kennedy, Breandán N.
Publicado 2016

The Mitochondrial Genes BAK1, FIS1 and SFN are Linked with Alterations in Mitochondrial Membrane Potential in Barrett’s Esophagus

por Phelan, James J., MacCarthy, Finbar, O’Toole, Dermot, Ravi, Narayanasamy, Reynolds, John V., O’Sullivan, Jacintha
Publicado 2018

Decreased Mitochondrial DNA Mutagenesis in Human Colorectal Cancer

por Ericson, Nolan G., Kulawiec, Mariola, Vermulst, Marc, Sheahan, Kieran, O'Sullivan, Jacintha, Salk, Jesse J., Bielas, Jason H.
Publicado 2012

Altered Mitochondrial Function and Energy Metabolism Is Associated with a Radioresistant Phenotype in Oesophageal Adenocarcinoma

por Lynam-Lennon, Niamh, Maher, Stephen G., Maguire, Aoife, Phelan, James, Muldoon, Cian, Reynolds, John V., O’Sullivan, Jacintha
Publicado 2014

Effect of cigarette smoke extract on the intestinal microenvironment of ulcerative colitis tissue

por Cannon, Aoife, Clarke, Niamh, MacCarthy, Finbar, Dunne, Cara, Kevans, David, Mahmud, Nasir, Lysaght, Joanne, O'Sullivan, Jacintha
Publicado 2020

1,4-dihydroxy quininib attenuates growth of colorectal cancer cells and xenografts and regulates the TIE-2 signaling pathway in patient tumours

por Butler, Clare T., Kennedy, Susan A., Buckley, Amy, Doyle, Ronan, Conroy, Emer, Gallagher, William M., O’Sullivan, Jacintha, Kennedy, Breandán N.
Publicado 2019

Energy Metabolism Is Altered in Radioresistant Rectal Cancer

por Buckley, Croí E., Yin, Xiaofei, Meltzer, Sebastian, Ree, Anne Hansen, Redalen, Kathrine Røe, Brennan, Lorraine, O’Sullivan, Jacintha, Lynam-Lennon, Niamh
Publicado 2023

A prospective investigation of predictive and modifiable risk factors for breast cancer in unaffected BRCA1 and BRCA2 gene carriers

por Guinan, Emer M, Hussey, Juliette, McGarrigle, Sarah A, Healy, Laura A, O’Sullivan, Jacintha N, Bennett, Kathleen, Connolly, Elizabeth M
Publicado 2013

Identification of TLR2 Signalling Mechanisms Which Contribute to Barrett’s and Oesophageal Adenocarcinoma Disease Progression

por Flis, Ewelina, Barber, Gillian, Nulty, Ciara, Keogh, Brian, McGuirk, Peter, Anand, Akanksha, O’Sullivan, Jacintha, Quante, Michael, Creagh, Emma M.
Publicado 2021

Successful tumour necrosis factor (TNF) blocking therapy suppresses oxidative stress and hypoxia-induced mitochondrial mutagenesis in inflammatory arthritis

por Biniecka, Monika, Kennedy, Aisling, Ng, Chin T, Chang, Ting C, Balogh, Emese, Fox, Edward, Veale, Douglas J, Fearon, Ursula, O'Sullivan, Jacintha N
Publicado 2011

Heterogeneity of tumor-induced gene expression changes in the human metabolic network

por Hu, Jie, Locasale, Jason W., Bielas, Jason H., O’Sullivan, Jacintha, Sheahan, Kieran, Cantley, Lewis C., Vander Heiden, Matthew G., Vitkup, Dennis
Publicado 2013

Perspectives of Esophageal Cancer Survivors on Diagnosis, Treatment, and Recovery

por Bennett, Annemarie E., O’Neill, Linda, Connolly, Deirdre, Guinan, Emer, Boland, Lauren, Doyle, Suzanne, O’Sullivan, Jacintha, Reynolds, John V., Hussey, Juliette
Publicado 2020

Characterisation of an Isogenic Model of Cisplatin Resistance in Oesophageal Adenocarcinoma Cells

por Buckley, Amy M., Bibby, Becky AS., Dunne, Margaret R., Kennedy, Susan A., Davern, Maria B., Kennedy, Breandán N., Maher, Stephen G., O’Sullivan, Jacintha
Publicado 2019

Patient and family co-developed participant information to improve recruitment rates, retention, and patient understanding in the Rehabilitation Strategies Following Oesophago-gast...

por O'Neill, Linda, Knapp, Peter, Doyle, Suzanne L., Guinan, Emer, Parker, Adwoa, Segurado, Ricardo, Connolly, Deirdre, O'Sullivan, Jacintha, Reynolds, John V., Hussey, Juliette
Publicado 2020