Targeting peroxiredoxin 1 impairs growth of breast cancer cells and potently sensitises these cells to prooxidant agents

por Bajor, Malgorzata, Zych, Agata O., Graczyk-Jarzynka, Agnieszka, Muchowicz, Angelika, Firczuk, Malgorzata, Trzeciak, Lech, Gaj, Pawel, Domagala, Antoni, Siernicka, Marta, Zagozdzon, Agnieszka, Siedlecki, Pawel, Kniotek, Monika, O’Leary, Patrick C., Golab, Jakub, Zagozdzon, Radoslaw
Publicado 2018

Systematic antibody generation and validation via tissue microarray technology leading to identification of a novel protein prognostic panel in breast cancer

por O´Leary, Patrick C, Penny, Sarah A, Dolan, Roisin T, Kelly, Catherine M, Madden, Stephen F, Rexhepaj, Elton, Brennan, Donal J, McCann, Amanda H, Pontén, Fredrik, Uhlén, Mathias, Zagozdzon, Radoslaw, Duffy, Michael J, Kell, Malcolm R, Jirström, Karin, Gallagher, William M
Publicado 2013

A single inactivating amino acid change in the SARS-CoV-2 NSP3 Mac1 domain attenuates viral replication and pathogenesis in vivo

por Taha, Taha Y., Suryawanshi, Rahul K., Chen, Irene P., Correy, Galen J., O’Leary, Patrick C., Jogalekar, Manasi P., McCavitt-Malvido, Maria, Diolaiti, Morgan E., Kimmerly, Gabriella R., Tsou, Chia-Lin, Martinez-Sobrido, Luis, Krogan, Nevan J., Ashworth, Alan, Fraser, James S., Ott, Melanie
Publicado 2023

A single inactivating amino acid change in the SARS-CoV-2 NSP3 Mac1 domain attenuates viral replication in vivo

por Taha, Taha Y., Suryawanshi, Rahul K., Chen, Irene P., Correy, Galen J., McCavitt-Malvido, Maria, O’Leary, Patrick C., Jogalekar, Manasi P., Diolaiti, Morgan E., Kimmerly, Gabriella R., Tsou, Chia-Lin, Gascon, Ronnie, Montano, Mauricio, Martinez-Sobrido, Luis, Krogan, Nevan J., Ashworth, Alan, Fraser, James S., Ott, Melanie
Publicado 2023

Peroxiredoxin-1 protects estrogen receptor α from oxidative stress-induced suppression and is a protein biomarker of favorable prognosis in breast cancer

por O’Leary, Patrick C, Terrile, Marta, Bajor, Malgorzata, Gaj, Pawel, Hennessy, Bryan T, Mills, Gordon B, Zagozdzon, Agnieszka, O’Connor, Darran P, Brennan, Donal J, Connor, Kate, Li, Jane, Gonzalez-Angulo, Ana Maria, Sun, Han-Dong, Pu, Jian-Xin, Pontén, Fredrik, Uhlén, Mathias, Jirström, Karin, Nowis, Dominika A, Crown, John P, Zagozdzon, Radoslaw, Gallagher, William M
Publicado 2014