RNA sequencing of synaptic and cytoplasmic Upf1-bound transcripts supports contribution of nonsense-mediated decay to epileptogenesis

por Mooney, Claire M., Jimenez-Mateos, Eva M., Engel, Tobias, Mooney, Catherine, Diviney, Mairead, Venø, Morten T., Kjems, Jørgen, Farrell, Michael A., O’Brien, Donncha F., Delanty, Norman, Henshall, David C.
Publicado 2017

Reduced Mature MicroRNA Levels in Association with Dicer Loss in Human Temporal Lobe Epilepsy with Hippocampal Sclerosis

por McKiernan, Ross C., Jimenez-Mateos, Eva M., Bray, Isabella, Engel, Tobias, Brennan, Gary P., Sano, Takanori, Michalak, Zuzanna, Moran, Catherine, Delanty, Norman, Farrell, Michael, O’Brien, Donncha, Meller, Robert, Simon, Roger P., Stallings, Raymond L., Henshall, David C.
Publicado 2012

MicroRNA inhibition using antimiRs in acute human brain tissue sections

por Morris, Gareth, Langa, Elena, Fearon, Conor, Conboy, Karen, Lau E‐How, Kelvin, Sanz‐Rodriguez, Amaya, O'Brien, Donncha F., Sweeney, Kieron, Lacey, Austin, Delanty, Norman, Beausang, Alan, Brett, Francesca M., Cryan, Jane B., Cunningham, Mark O., Henshall, David C.
Publicado 2022

Potent Anti-seizure Effects of Locked Nucleic Acid Antagomirs Targeting miR-134 in Multiple Mouse and Rat Models of Epilepsy

por Reschke, Cristina R., Silva, Luiz F. Almeida, Norwood, Braxton A., Senthilkumar, Ketharini, Morris, Gareth, Sanz-Rodriguez, Amaya, Conroy, Ronán M., Costard, Lara, Neubert, Valentin, Bauer, Sebastian, Farrell, Michael A., O’Brien, Donncha F., Delanty, Norman, Schorge, Stephanie, Pasterkamp, R. Jeroen, Rosenow, Felix, Henshall, David C.
Publicado 2017

Cerebrospinal fluid microRNAs are potential biomarkers of temporal lobe epilepsy and status epilepticus

por Raoof, Rana, Jimenez-Mateos, Eva M., Bauer, Sebastian, Tackenberg, Björn, Rosenow, Felix, Lang, Johannes, Onugoren, Müjgan Dogan, Hamer, Hajo, Huchtemann, Tessa, Körtvélyessy, Peter, Connolly, Niamh M. C., Pfeiffer, Shona, Prehn, Jochen H. M., Farrell, Michael A., O’Brien, Donncha F., Henshall, David C., Mooney, Catherine
Publicado 2017

Silencing microRNA-134 produces neuroprotective and prolonged seizure-suppressive effects

por Jimenez-Mateos, Eva M., Engel, Tobias, Merino-Serrais, Paula, McKiernan, Ross C., Tanaka, Katsuhiro, Mouri, Genshin, Sano, Takanori, O’Tuathaigh, Colm, Waddington, John L., Prenter, Suzanne, Delanty, Norman, Farrell, Michael A., O’Brien, Donncha F., Conroy, Ronán M., Stallings, Raymond L., deFelipe, Javier, Henshall, David C.
Publicado 2012

Microvascular stabilization via blood-brain barrier regulation prevents seizure activity

por Greene, Chris, Hanley, Nicole, Reschke, Cristina R., Reddy, Avril, Mäe, Maarja A., Connolly, Ruairi, Behan, Claire, O’Keeffe, Eoin, Bolger, Isobel, Hudson, Natalie, Delaney, Conor, Farrell, Michael A., O’Brien, Donncha F., Cryan, Jane, Brett, Francesca M., Beausang, Alan, Betsholtz, Christer, Henshall, David C., Doherty, Colin P., Campbell, Matthew
Publicado 2022

MicroRNA-22 Controls Aberrant Neurogenesis and Changes in Neuronal Morphology After Status Epilepticus

por Beamer, Edward H., Jurado-Arjona, Jeronimo, Jimenez-Mateos, Eva M., Morgan, James, Reschke, Cristina R., Kenny, Aidan, de Leo, Gioacchino, Olivos-Oré, Luis A., Arribas-Blázquez, Marina, Madden, Stephen F., Merchán-Rubira, Jesús, Delanty, Norman, Farrell, Michael A., O’Brien, Donncha F., Avila, Jesus, Diaz-Hernandez, Miguel, Miras-Portugal, M. Teresa, Artalejo, Antonio R., Hernandez, Felix, Henshall, David C., Engel, Tobias
Publicado 2018