Phase 1b study of lenvatinib (E7080) in combination with temozolomide for treatment of advanced melanoma

por Hong, David S., Kurzrock, Razelle, Falchook, Gerald S., Andresen, Corina, Kwak, Jennifer, Ren, Min, Xu, Lucy, George, Goldy C., Kim, Kevin B., Nguyen, Ly M., O'Brien, James P., Nemunaitis, John
Publicado 2015

Targeting the EMT transcription factor TWIST1 overcomes resistance to EGFR inhibitors in EGFR-mutant non-small cell lung cancer

por Yochum, Zachary A., Cades, Jessica, Wang, Hailun, Chatterjee, Suman, Simons, Brian W., O’Brien, James P., Khetarpal, Susheel K., Lemtiri-Chlieh, Ghali, Myers, Kayla V., Huang, Eric H.-B., Rudin, Charles M., Tran, Phuoc T., Burns, Timothy F.
Publicado 2018

Nitroalkene fatty acids modulate bile acid metabolism and lung function in obese asthma

por Manni, Michelle L., Heinrich, Victoria A., Buchan, Gregory J., O’Brien, James P., Uvalle, Crystal, Cechova, Veronika, Koudelka, Adolf, Ukani, Dharti, Rawas-Qalaji, Mohamad, Oury, Tim D., Hart, Renee, Ellgass, Madeline, Mullett, Steven J., Fajt, Merritt L., Wenzel, Sally E., Holguin, Fernando, Freeman, Bruce A., Wendell, Stacy G.
Publicado 2021

A phase 2 trial of lenvatinib (E7080) in advanced, progressive, radioiodine‐refractory, differentiated thyroid cancer: A clinical outcomes and biomarker assessment

por Cabanillas, Maria E., Schlumberger, Martin, Jarzab, Barbara, Martins, Renato G., Pacini, Furio, Robinson, Bruce, McCaffrey, Judith C., Shah, Manisha H., Bodenner, Donald L., Topliss, Duncan, Andresen, Corina, O'Brien, James P., Ren, Min, Funahashi, Yasuhiro, Allison, Roger, Elisei, Rossella, Newbold, Kate, Licitra, Lisa F., Sherman, Steven I., Ball, Douglas W.
Publicado 2015

Pyruvate Kinase M1 Suppresses Development and Progression of Prostate Adenocarcinoma

por Davidson, Shawn M., Schmidt, Daniel R., Heyman, Julia E., O'Brien, James P., Liu, Amy C., Israelsen, William J., Dayton, Talya L., Sehgal, Raghav, Bronson, Roderick T., Freinkman, Elizaveta, Mak, Howard H., Fanelli, Giuseppe Nicolò, Malstrom, Scott, Bellinger, Gary, Carracedo, Arkaitz, Pandolfi, Pier Paolo, Courtney, Kevin D., Jha, Abhishek, DePinho, Ronald A., Horner, James W., Thomas, Craig J., Cantley, Lewis C., Loda, Massimo, Vander Heiden, Matthew G.
Publicado 2022