Total Synthesis of Tetrahydrolipstatin and Stereoisomers via a Highly Regio- and Diastereoselective Carbonylation of Epoxyhomoallylic Alcohols

por Mulzer, Michael, Tiegs, Brandon J., Wang, Yanping, Coates, Geoffrey W., O’Doherty, George A.
Publicado 2014

Cardiac glycoside ouabain efficiently targets leukemic stem cell apoptotic machinery independent of cell differentiation status

por Poohadsuan, Jirarat, O’Doherty, George A., Owattanapanich, Weerapat, Kungwankiattichai, Smith, Rojanasakul, Yon, Issaragrisil, Surapol, Luanpitpong, Sudjit
Publicado 2023

Identifying requirements for RSK2 specific inhibitors

por Wright, Eric B., Fukuda, Shinji, Li, Mingzong, Li, Yu, O’Doherty, George A., Lannigan, Deborah A.
Publicado 2021

Stereoselective Synthesis of β-Glycinamide Ribonucleotide

por Ngu, Lisa, Ray, Debarpita, Watson, Samantha S., Beuning, Penny J., Ondrechen, Mary Jo, O’Doherty, George A.
Publicado 2022

De Novo Synthesis and Biological Evaluation of C6″-Substituted C4″-Amide Analogues of SL0101

por Mrozowski, Roman M., Sandusky, Zachary M., Vemula, Rajender, Wu, Bulan, Zhang, Qi, Lannigan, Deborah A., O’Doherty, George A.
Publicado 2014

Digitoxin and its synthetic analog MonoD have potent antiproliferative effects on lung cancer cells and potentiate the effects of hydroxyurea and paclitaxel

por YAKISICH, JUAN SEBASTIAN, AZAD, NEELAM, VENKATADRI, RAJKUMAR, KULKARNI, YOGESH, WRIGHT, CLAYTON, KAUSHIK, VIVEK, O'DOHERTY, GEORGE A., IYER, ANAND KRISHNAN V.
Publicado 2016

RSK2 Maintains Adult Estrogen Homeostasis by Inhibiting ERK1/2-Mediated Degradation of Estrogen Receptor Alpha

por Ludwik, Katarzyna A., Sandusky, Zachary M., Stauffer, Kimberly M., Li, Yu, Boyd, Kelli L., O’Doherty, George A., Stricker, Thomas P., Lannigan, Deborah A.
Publicado 2020