An explanation for origin unwinding in eukaryotes

por Langston, Lance D, O'Donnell, Michael E
Publicado 2019

Getting ready for DNA duplication

por Yao, Nina Y, O'Donnell, Michael E
Publicado 2019

Anatomy of a twin DNA replication factory

por Li, Huilin, Yao, Nina Y., O'Donnell, Michael E.
Publicado 2020

Molecular choreography of primer synthesis by the eukaryotic Pol α-primase

por Yuan, Zuanning, Georgescu, Roxana, Li, Huilin, O’Donnell, Michael E.
Publicado 2023

Molecular choreography of primer synthesis by the eukaryotic Pol α-primase

por Yuan, Zuanning, Georgescu, Roxana, Li, Huilin, O’Donnell, Michael E.
Publicado 2023

Structure of eukaryotic DNA polymerase δ bound to the PCNA clamp while encircling DNA

por Zheng, Fengwei, Georgescu, Roxana E., Li, Huilin, O’Donnell, Michael E.
Publicado 2020

CMG helicase can use ATPγS to unwind DNA: Implications for the rate-limiting step in the reaction mechanism

por Yao, Nina Y., Zhang, Dan, Yurieva, Olga, O’Donnell, Michael E.
Publicado 2022

Structure of the polymerase ε holoenzyme and atomic model of the leading strand replisome

por Yuan, Zuanning, Georgescu, Roxana, Schauer, Grant D., O’Donnell, Michael E., Li, Huilin
Publicado 2020

Cryo-EM structures reveal that RFC recognizes both the 3′- and 5′-DNA ends to load PCNA onto gaps for DNA repair

por Zheng, Fengwei, Georgescu, Roxana, Yao, Nina Y, Li, Huilin, O'Donnell, Michael E
Publicado 2022

SV40 T-antigen uses a DNA shearing mechanism to initiate origin unwinding

por Langston, Lance D., Yuan, Zuanning, Georgescu, Roxana, Li, Huilin, O’Donnell, Michael E.
Publicado 2022

Structures of 9-1-1 DNA checkpoint clamp loading at gaps from start to finish and ramification to biology

por Zheng, Fengwei, Georgescu, Roxana E., Yao, Nina Y., O’Donnell, Michael E., Li, Huilin
Publicado 2023

Structures of 9-1-1 DNA checkpoint clamp loading at gaps from start to finish and ramification on biology

por Zheng, Fengwei, Georgescu, Roxana E., Yao, Nina Y., O’Donnell, Michael E., Li, Huilin
Publicado 2023

DNA unwinding mechanism of a eukaryotic replicative CMG helicase

por Yuan, Zuanning, Georgescu, Roxana, Bai, Lin, Zhang, Dan, Li, Huilin, O’Donnell, Michael E.
Publicado 2020

DNA is loaded through the 9-1-1 DNA checkpoint clamp in the opposite direction of the PCNA clamp

por Zheng, Fengwei, Georgescu, Roxana E., Yao, Nina Y., O’Donnell, Michael E., Li, Huilin
Publicado 2022

Mcm10 has potent strand-annealing activity and limits translocase-mediated fork regression

por Mayle, Ryan, Langston, Lance, Molloy, Kelly R., Zhang, Dan, Chait, Brian T., O’Donnell, Michael E.
Publicado 2019

Nucleosome-directed replication origin licensing independent of a consensus DNA sequence

por Li, Sai, Wasserman, Michael R., Yurieva, Olga, Bai, Lu, O’Donnell, Michael E., Liu, Shixin
Publicado 2022

Origin recognition complex harbors an intrinsic nucleosome remodeling activity

por Li, Sai, Wasserman, Michael R., Yurieva, Olga, Bai, Lu, O’Donnell, Michael E., Liu, Shixin
Publicado 2022

Structure of the eukaryotic replicative CMG helicase and pumpjack motion

por Yuan, Zuanning, Bai, Lin, Sun, Jingchuan, Georgescu, Roxana, Liu, Jun, O’Donnell, Michael E., Li, Huilin
Publicado 2016

Mutagenic cost of ribonucleotides in bacterial DNA

por Schroeder, Jeremy W., Randall, Justin R., Hirst, William G., O’Donnell, Michael E., Simmons, Lyle A.
Publicado 2017

Allosteric communication in DNA polymerase clamp loaders relies on a critical hydrogen-bonded junction

por Subramanian, Subu, Gorday, Kent, Marcus, Kendra, Orellana, Matthew R, Ren, Peter, Luo, Xiao Ran, O'Donnell, Michael E, Kuriyan, John
Publicado 2021