Targeted treatment of advanced and metastaticbreast cancer with lapatinib

por Corkery, Brendan, O’Donovan, Norma, Crown, John
Publicado 2008

Alterations in integrin expression modulates invasion of pancreatic cancer cells

por Walsh, Naomi, Clynes, Martin, Crown, John, O'Donovan, Norma
Publicado 2009

Preclinical evaluation of dasatinib, a potent Src kinase inhibitor, in melanoma cell lines

por Eustace, Alex J, Crown, John, Clynes, Martin, O'Donovan, Norma
Publicado 2008

The 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors, simvastatin, lovastatin and mevastatin inhibit proliferation and invasion of melanoma cells

por Glynn, Sharon A, O'Sullivan, Dermot, Eustace, Alex J, Clynes, Martin, O'Donovan, Norma
Publicado 2008

Systems modeling accurately predicts responses to genotoxic agents and their synergism with BCL-2 inhibitors in triple negative breast cancer cells

por Lucantoni, Federico, Lindner, Andreas U., O’Donovan, Norma, Düssmann, Heiko, Prehn, Jochen H. M.
Publicado 2018

Identification of pancreatic cancer invasion-related proteins by proteomic analysis

por Walsh, Naomi, O'Donovan, Norma, Kennedy, Susan, Henry, Michael, Meleady, Paula, Clynes, Martin, Dowling, Paul
Publicado 2009

Identification of potential new treatment response markers and therapeutic targets using a Gaussian process-based method in lapatinib insensitive breast cancer models

por Santra, Tapesh, Roche, Sandra, Conlon, Neil, O’Donovan, Norma, Crown, John, O’Connor, Robert, Kolch, Walter
Publicado 2017

The ADAMs family of proteases: new biomarkers and therapeutic targets for cancer?

por Duffy, Michael J, Mullooly, Maeve, O'Donovan, Norma, Sukor, Sumainizah, Crown, John, Pierce, Aisling, McGowan, Patricia M
Publicado 2011

In vitro Development of Chemotherapy and Targeted Therapy Drug-Resistant Cancer Cell Lines: A Practical Guide with Case Studies

por McDermott, Martina, Eustace, Alex J., Busschots, Steven, Breen, Laura, Crown, John, Clynes, Martin, O’Donovan, Norma, Stordal, Britta
Publicado 2014

BreastMark: An Integrated Approach to Mining Publicly Available Transcriptomic Datasets Relating to Breast Cancer Outcome

por Madden, Stephen F, Clarke, Colin, Gaule, Patricia, Aherne, Sinead T, O'Donovan, Norma, Clynes, Martin, Crown, John, Gallagher, William M
Publicado 2013

ADAM10: a new player in breast cancer progression?

por Mullooly, Maeve, McGowan, Patricia M, Kennedy, Susan A, Madden, Stephen F, Crown, John, O' Donovan, Norma, Duffy, Michael J
Publicado 2015

Predictive biomarkers for dasatinib treatment in melanoma

por Eustace, Alex J., Kennedy, Susan, Larkin, Anne-Marie, Mahgoub, Thamir, Tryfonopoulos, Dimitrios, O'Driscoll, Lorraine, Clynes, Martin, Crown, John, O'Donovan, Norma
Publicado 2014

A Systems Biology Approach to Investigate Kinase Signal Transduction Networks That Are Involved in Triple Negative Breast Cancer Resistance to Cisplatin

por Mukherjee, Nupur, Browne, Alacoque, Ivers, Laura, Santra, Tapesh, Cremona, Mattia, Hennessy, Bryan T., O’Donovan, Norma, Crown, John, Kolch, Walter, Fey, Dirk, Eustace, Alex J.
Publicado 2022

HER2-Targeted Tyrosine Kinase Inhibitors Cause Therapy-Induced-Senescence in Breast Cancer Cells

por McDermott, Martina S. J., Conlon, Neil, Browne, Brigid C., Szabo, Adam, Synnott, Naoise C., O’Brien, Neil A., Duffy, Michael J., Crown, John, O’Donovan, Norma
Publicado 2019

Investigation of the molecular profile of basal cell carcinoma using whole genome microarrays

por O'Driscoll, Lorraine, McMorrow, Jason, Doolan, Padraig, McKiernan, Eadaoin, Mehta, Jai Prakash, Ryan, Eoin, Gammell, Patrick, Joyce, Helena, O'Donovan, Norma, Walsh, Nicholas, Clynes, Martin
Publicado 2006

Correction: PP2A inhibition overcomes acquired resistance to HER2 targeted therapy

por McDermott, Martina S. J., Browne, Brigid C., Conlon, Neil T., O’Brien, Neil A., Slamon, Dennis J., Henry, Michael, Meleady, Paula, Clynes, Martin, Dowling, Paul, Crown, John, O’Donovan, Norma
Publicado 2023

PP2A inhibition overcomes acquired resistance to HER2 targeted therapy

por McDermott, Martina SJ, Browne, Brigid C, Conlon, Neil T, O’Brien, Neil A, Slamon, Dennis J, Henry, Michael, Meleady, Paula, Clynes, Martin, Dowling, Paul, Crown, John, O’Donovan, Norma
Publicado 2014

Dasatinib Treatment Increases Sensitivity to c-Met Inhibition in Triple-Negative Breast Cancer Cells

por Gaule, Patricia, Mukherjee, Nupur, Corkery, Brendan, Eustace, Alex J., Gately, Kathy, Roche, Sandra, O’Connor, Robert, O’Byrne, Kenneth J., Walsh, Naomi, Duffy, Michael J., Crown, John, O’Donovan, Norma
Publicado 2019

Preclinical evaluation of Insulin-like growth factor receptor 1 (IGF1R) and Insulin Receptor (IR) as a therapeutic targets in triple negative breast cancer

por Roche, Sandra, Gaule, Patricia, Winrow, Deirdre, Mukherjee, Nupur, O’Neill, Fiona, Conlon, Neil T., Meiller, Justine, Collins, Denis M., Canonici, Alexandra, Fawsi, Mohammed Ibrahim, Estepa-Fernández, Alejandra, Madden, Stephen F., Crown, John, O’Donovan, Norma, Eustace, Alex J.
Publicado 2023

Combined targeting EGFR and SRC as a potential novel therapeutic approach for the treatment of triple negative breast cancer

por Canonici, Alexandra, Browne, Alacoque L., Ibrahim, Mohamed F. K., Fanning, Kevin P., Roche, Sandra, Conlon, Neil T., O’Neill, Fiona, Meiller, Justine, Cremona, Mattia, Morgan, Clare, Hennessy, Bryan T., Eustace, Alex J., Solca, Flavio, O’Donovan, Norma, Crown, John
Publicado 2020