Analysis of high-dimensional metabolomics data with complex temporal dynamics using RM-ASCA+

por Erdős, Balázs, Westerhuis, Johan A., Adriaens, Michiel E., O’Donovan, Shauna D., Xie, Ren, Singh-Povel, Cécile M., Smilde, Age K., Arts, Ilja C. W.
Publicado 2023

Personalized computational model quantifies heterogeneity in postprandial responses to oral glucose challenge

por Erdős, Balázs, van Sloun, Bart, Adriaens, Michiel E., O’Donovan, Shauna D., Langin, Dominique, Astrup, Arne, Blaak, Ellen E., Arts, Ilja C. W., van Riel, Natal A. W.
Publicado 2021

E-DES-PROT: A novel computational model to describe the effects of amino acids and protein on postprandial glucose and insulin dynamics in humans

por van Sloun, Bart, Goossens, Gijs H., Erdõs, Balázs, O’Donovan, Shauna D., Singh-Povel, Cécile M., Geurts, Jan M.W., van Riel, Natal A.W., Arts, Ilja C.W.
Publicado 2023

Quantifying the contribution of triglycerides to metabolic resilience through the mixed meal model

por O’Donovan, Shauna D., Erdős, Balázs, Jacobs, Doris M., Wanders, Anne J., Thomas, E. Louise, Bell, Jimmy D., Rundle, Milena, Frost, Gary, Arts, Ilja C.W., Afman, Lydia A., van Riel, Natal A.W.
Publicado 2022

Application of transfer learning to predict drug-induced human in vivo gene expression changes using rat in vitro and in vivo data

por O’Donovan, Shauna D., Cavill, Rachel, Wimmenauer, Florian, Lukas, Alexander, Stumm, Tobias, Smirnov, Evgueni, Lenz, Michael, Ertaylan, Gokhan, Jennen, Danyel G. J., van Riel, Natal A. W., Driessens, Kurt, Peeters, Ralf L. M., de Kok, Theo M. C. M.
Publicado 2023

A computational model of postprandial adipose tissue lipid metabolism derived using human arteriovenous stable isotope tracer data

por O’Donovan, Shauna D., Lenz, Michael, Vink, Roel G., Roumans, Nadia J. T., de Kok, Theo M. C. M., Mariman, Edwin C. M., Peeters, Ralf L. M., van Riel, Natal A. W., van Baak, Marleen A., Arts, Ilja C. W.
Publicado 2019

Quantifying postprandial glucose responses using a hybrid modeling approach: Combining mechanistic and data-driven models in The Maastricht Study

por Erdős, Balázs, van Sloun, Bart, Goossens, Gijs H., O’Donovan, Shauna D., de Galan, Bastiaan E., van Greevenbroek, Marleen M. J., Stehouwer, Coen D. A., Schram, Miranda T., Blaak, Ellen E., Adriaens, Michiel E., van Riel, Natal A. W., Arts, Ilja C. W.
Publicado 2023

Use of deep learning methods to translate drug-induced gene expression changes from rat to human primary hepatocytes

por O’Donovan, Shauna D., Driessens, Kurt, Lopatta, Daniel, Wimmenauer, Florian, Lukas, Alexander, Neeven, Jelmer, Stumm, Tobias, Smirnov, Evgueni, Lenz, Michael, Ertaylan, Gokhan, Jennen, Danyel G. J., van Riel, Natal A. W., Cavill, Rachel, Peeters, Ralf L. M., de Kok, Theo M. C. M.
Publicado 2020

Improved quantification of muscle insulin sensitivity using oral glucose tolerance test data: the MISI Calculator

por O’Donovan, Shauna D., Lenz, Michael, Goossens, Gijs H., van der Kallen, Carla J. H., Eussen, Simone J. M. P., Stehouwer, Coen D. A., van Greevenbroek, Marleen M., Schram, Miranda T., Sep, Simone J., Peeters, Ralf L. M., Blaak, Ellen E., van Riel, Natal A. W., de Kok, Theo M. C. M., Arts, Ilja C. W.
Publicado 2019