ZNF274 Recruits the Histone Methyltransferase SETDB1 to the 3′ Ends of ZNF Genes

por Frietze, Seth, O'Geen, Henriette, Blahnik, Kimberly R., Jin, Victor X., Farnham, Peggy J.
Publicado 2010

A genome-wide analysis of Cas9 binding specificity using ChIP-seq and targeted sequence capture

por O'Geen, Henriette, Henry, Isabelle M., Bhakta, Mital S., Meckler, Joshua F., Segal, David J.
Publicado 2015

Unexpected binding behaviors of bacterial Argonautes in human cells cast doubts on their use as targetable gene regulators

por O’Geen, Henriette, Ren, Chonghua, Coggins, Nicole B., Bates, Sofie L., Segal, David J.
Publicado 2018

Determinants of heritable gene silencing for KRAB-dCas9 + DNMT3 and Ezh2-dCas9 + DNMT3 hit-and-run epigenome editing

por O’Geen, Henriette, Tomkova, Marketa, Combs, Jacquelyn A, Tilley, Emma K, Segal, David J
Publicado 2022

Methods for Scarless, Selection-Free Generation of Human Cells and Allele-Specific Functional Analysis of Disease-Associated SNPs and Variants of Uncertain Significance

por Coggins, Nicole B., Stultz, Jacob, O’Geen, Henriette, Carvajal-Carmona, Luis G., Segal, David J.
Publicado 2017

Author Correction: Methods for Scarless, Selection-Free Generation of Human Cells and Allele-Specific Functional Analysis of Disease-Associated SNPs and Variants of Uncertain Signi...

por Coggins, Nicole B., Stultz, Jacob, O’Geen, Henriette, Carvajal-Carmona, Luis G., Segal, David J.
Publicado 2018

Imaging Unique DNA Sequences in Individual Cells Using a CRISPR-Cas9-Based, Split Luciferase Biosensor

por Heath, Nicholas G., O’Geen, Henriette, Halmai, Nicole B., Corn, Jacob E., Segal, David J.
Publicado 2022

Aberrant promoter methylation contributes to LRIG1 silencing in basal/triple-negative breast cancer

por Umeh-Garcia, Maxine, O’Geen, Henriette, Simion, Catalina, Gephart, Melanie Hayden, Segal, David J., Sweeney, Colleen A.
Publicado 2022

Global analysis of ZNF217 chromatin occupancy in the breast cancer cell genome reveals an association with ERalpha

por Frietze, Seth, O’Geen, Henriette, Littlepage, Laurie E, Simion, Catalina, Sweeney, Colleen A, Farnham, Peggy J, Krig, Sheryl R
Publicado 2014

Endogenous mammalian histone H3.3 exhibits chromatin-related functions during development

por Bush, Kelly M, Yuen, Benjamin TK, Barrilleaux, Bonnie L, Riggs, John W, O’Geen, Henriette, Cotterman, Rebecca F, Knoepfler, Paul S
Publicado 2013

Genome-Wide Analysis of KAP1 Binding Suggests Autoregulation of KRAB-ZNFs

por O'Geen, Henriette, Squazzo, Sharon L, Iyengar, Sushma, Blahnik, Kim, Rinn, John L, Chang, Howard Y, Green, Roland, Farnham, Peggy J
Publicado 2007

Effects on the transcriptome upon deletion of a distal element cannot be predicted by the size of the H3K27Ac peak in human cells

por Tak, Yu Gyoung, Hung, Yuli, Yao, Lijing, Grimmer, Matthew R., Do, Albert, Bhakta, Mital S., O'Geen, Henriette, Segal, David J., Farnham, Peggy J.
Publicado 2016

dCas9-based epigenome editing suggests acquisition of histone methylation is not sufficient for target gene repression

por O’Geen, Henriette, Ren, Chonghua, Nicolet, Charles M., Perez, Andrew A., Halmai, Julian, Le, Victoria M., Mackay, Joel P., Farnham, Peggy J., Segal, David J.
Publicado 2017

Ezh2-dCas9 and KRAB-dCas9 enable engineering of epigenetic memory in a context-dependent manner

por O’Geen, Henriette, Bates, Sofie L., Carter, Sakereh S., Nisson, Karly A., Halmai, Julian, Fink, Kyle D., Rhie, Suhn K., Farnham, Peggy J., Segal, David J.
Publicado 2019

Diverse Molecular Mechanisms Contribute to Differential Expression of Human Duplicated Genes

por Shew, Colin J, Carmona-Mora, Paulina, Soto, Daniela C, Mastoras, Mira, Roberts, Elizabeth, Rosas, Joseph, Jagannathan, Dhriti, Kaya, Gulhan, O’Geen, Henriette, Dennis, Megan Y
Publicado 2021

Functional rescue in an Angelman syndrome model following treatment with lentivector transduced hematopoietic stem cells

por Adhikari, Anna, Copping, Nycole A, Beegle, Julie, Cameron, David L, Deng, Peter, O’Geen, Henriette, Segal, David J, Fink, Kyle D, Silverman, Jill L, Anderson, Joseph S
Publicado 2021

Sole-Search: an integrated analysis program for peak detection and functional annotation using ChIP-seq data

por Blahnik, Kimberly R., Dou, Lei, O’Geen, Henriette, McPhillips, Timothy, Xu, Xiaoqin, Cao, Alina R., Iyengar, Sushma, Nicolet, Charles M., Ludäscher, Bertram, Korf, Ian, Farnham, Peggy J.
Publicado 2010

Characterization of the Contradictory Chromatin Signatures at the 3′ Exons of Zinc Finger Genes

por Blahnik, Kimberly R., Dou, Lei, Echipare, Lorigail, Iyengar, Sushma, O'Geen, Henriette, Sanchez, Erica, Zhao, Yongjun, Marra, Marco A., Hirst, Martin, Costello, Joseph F., Korf, Ian, Farnham, Peggy J.
Publicado 2011

Spark: A navigational paradigm for genomic data exploration

por Nielsen, Cydney B., Younesy, Hamid, O'Geen, Henriette, Xu, Xiaoqin, Jackson, Andrew R., Milosavljevic, Aleksandar, Wang, Ting, Costello, Joseph F., Hirst, Martin, Farnham, Peggy J., Jones, Steven J.M.
Publicado 2012

Protein Delivery of an Artificial Transcription Factor Restores Widespread Ube3a Expression in an Angelman Syndrome Mouse Brain

por Bailus, Barbara J, Pyles, Benjamin, McAlister, Michelle M, O'Geen, Henriette, Lockwood, Sarah H, Adams, Alexa N, Nguyen, Jennifer Trang T, Yu, Abigail, Berman, Robert F, Segal, David J
Publicado 2016