Treatment with the PARP inhibitor, niraparib, sensitizes colorectal cancer cell lines to irinotecan regardless of MSI/MSS status

por Genther Williams, Sybil M, Kuznicki, Apryle M, Andrade, Paula, Dolinski, Brian M, Elbi, Cem, O’Hagan, Ronan C, Toniatti, Carlo
Publicado 2015

A Potent and Selective ULK1 Inhibitor Suppresses Autophagy and Sensitizes Cancer Cells to Nutrient Stress

por Martin, Katie R., Celano, Stephanie L., Solitro, Abigail R., Gunaydin, Hakan, Scott, Mark, O'Hagan, Ronan C., Shumway, Stuart D., Fuller, Peter, MacKeigan, Jeffrey P.
Publicado 2018

Identification of Kinases Responsible for p53-Dependent Autophagy

por Celano, Stephanie L., Yco, Lisette P., Kortus, Matthew G., Solitro, Abigail R., Gunaydin, Hakan, Scott, Mark, Spooner, Edward, O'Hagan, Ronan C., Fuller, Peter, Martin, Katie R., Shumway, Stuart D., MacKeigan, Jeffrey P.
Publicado 2019

Discovery of a chemical probe for PRDM9

por Allali-Hassani, Abdellah, Szewczyk, Magdalena M., Ivanochko, Danton, Organ, Shawna L., Bok, Jabez, Ho, Jessica Sook Yuin, Gay, Florence P. H., Li, Fengling, Blazer, Levi, Eram, Mohammad S., Halabelian, Levon, Dilworth, David, Luciani, Genna M., Lima-Fernandes, Evelyne, Wu, Qin, Loppnau, Peter, Palmer, Nathan, Talib, S. Zakiah A., Brown, Peter J., Schapira, Matthieu, Kaldis, Philipp, O’Hagan, Ronan C., Guccione, Ernesto, Barsyte-Lovejoy, Dalia, Arrowsmith, Cheryl H., Sanders, John M., Kattar, Solomon D., Bennett, D. Jonathan, Nicholson, Benjamin, Vedadi, Masoud
Publicado 2019

Donated chemical probes for open science

por Müller, Susanne, Ackloo, Suzanne, Arrowsmith, Cheryl H, Bauser, Marcus, Baryza, Jeremy L, Blagg, Julian, Böttcher, Jark, Bountra, Chas, Brown, Peter J, Bunnage, Mark E, Carter, Adrian J, Damerell, David, Dötsch, Volker, Drewry, David H, Edwards, Aled M, Edwards, James, Elkins, Jon M, Fischer, Christian, Frye, Stephen V, Gollner, Andreas, Grimshaw, Charles E, IJzerman, Adriaan, Hanke, Thomas, Hartung, Ingo V, Hitchcock, Steve, Howe, Trevor, Hughes, Terry V, Laufer, Stefan, Li, Volkhart MJ, Liras, Spiros, Marsden, Brian D, Matsui, Hisanori, Mathias, John, O'Hagan, Ronan C, Owen, Dafydd R, Pande, Vineet, Rauh, Daniel, Rosenberg, Saul H, Roth, Bryan L, Schneider, Natalie S, Scholten, Cora, Singh Saikatendu, Kumar, Simeonov, Anton, Takizawa, Masayuki, Tse, Chris, Thompson, Paul R, Treiber, Daniel K, Viana, Amélia YI, Wells, Carrow I, Willson, Timothy M, Zuercher, William J, Knapp, Stefan, Mueller-Fahrnow, Anke
Publicado 2018