Understanding the Role of Mesenchymal Stromal Cells in Treating COVID-19 Acute Respiratory Distress Syndrome

por O’Kane, Cecilia M., Matthay, Michael A.
Publicado 2022

Precision‐cut lung slices: A powerful ex vivo model to investigate respiratory infectious diseases

por Viana, Flávia, O’Kane, Cecilia M., Schroeder, Gunnar N.
Publicado 2021

Simvastatin decreases the level of heparin-binding protein in patients with acute lung injury

por McAuley, Daniel F, O’Kane, Cecilia M, Craig, Thelma R, Shyamsundar, Murali, Herwald, Heiko, Dib, Karim
Publicado 2013

Keratinocyte growth factor in acute lung injury to reduce pulmonary dysfunction – a randomised placebo-controlled trial (KARE): study protocol

por Cross, Laurence JM, O’Kane, Cecilia M, McDowell, Cliona, Elborn, Jospeh J, Matthay, Michael A, McAuley, Daniel F
Publicado 2013

A randomized clinical trial of ascorbic acid in open abdominal aortic aneurysm repair

por Duffy, Martin J, O’Kane, Cecilia M, Stevenson, Michael, Young, Ian S, Harkin, Denis W, Mullan, Brian A, McAuley, Daniel F
Publicado 2015

Erratum to: Keratinocyte growth factor in acute lung injury to reduce pulmonary dysfunction – a randomised placebo-controlled trial (KARE): study protocol

por Cross, Laurence J. M., O’Kane, Cecilia M., McDowell, Cliona, Elborn, Jospeh J., Matthay, Michael A., McAuley, Daniel F.
Publicado 2017

A Porcine Ex Vivo Lung Perfusion Model To Investigate Bacterial Pathogenesis

por Dumigan, Amy, Fitzgerald, Marianne, Santos, Joana Sá-Pessoa Graca, Hamid, Umar, O’Kane, Cecilia M., McAuley, Danny F., Bengoechea, Jose A.
Publicado 2019

Baseline plasma IL-18 may predict simvastatin treatment response in patients with ARDS: a secondary analysis of the HARP-2 randomised clinical trial

por Boyle, Andrew James, Ferris, Peter, Bradbury, Ian, Conlon, John, Shankar-Hari, Manu, Rogers, Angela J., O’Kane, Cecilia M., McAuley, Daniel F.
Publicado 2022

The relationship between plasma cystatin C, mortality and acute respiratory distress syndrome subphenotype in the HARP-2 trial

por McKelvey, Michael C., Bradbury, Ian, McDowell, Cliona, Calfee, Carolyn S., Weldon, Sinead, O'Kane, Cecilia M., McAuley, Daniel F., Taggart, Clifford C.
Publicado 2023

Hydroxymethylglutaryl-CoA reductase inhibition with simvastatin in Acute lung injury to Reduce Pulmonary dysfunction (HARP-2) trial: study protocol for a randomized controlled tria...

por McAuley, Daniel F, Laffey, John G, O’Kane, Cecilia M, Cross, Mark, Perkins, Gavin D, Murphy, Lynn, McNally, Christine, Crealey, Grainne, Stevenson, Michael
Publicado 2012

Mitochondrial Transfer via Tunneling Nanotubes is an Important Mechanism by Which Mesenchymal Stem Cells Enhance Macrophage Phagocytosis in the In Vitro and In Vivo Models of ARDS

por Jackson, Megan V., Morrison, Thomas J., Doherty, Declan F., McAuley, Daniel F., Matthay, Michael A., Kissenpfennig, Adrien, O'Kane, Cecilia M., Krasnodembskaya, Anna D.
Publicado 2016

Hyperoxaemia and hypoxaemia are associated with harm in patients with ARDS

por Boyle, Andrew J., Holmes, David N., Hackett, Jonathan, Gilliland, Susanna, McCloskey, Michael, O’Kane, Cecilia M., Young, Paul, Di Gangi, Stefania, McAuley, Daniel F.
Publicado 2021

Identifying associations between diabetes and acute respiratory distress syndrome in patients with acute hypoxemic respiratory failure: an analysis of the LUNG SAFE database

por Boyle, Andrew J., Madotto, Fabiana, Laffey, John G., Bellani, Giacomo, Pham, Tài, Pesenti, Antonio, Thompson, B. Taylor, O’Kane, Cecilia M., Deane, Adam M., McAuley, Daniel F.
Publicado 2018

Effect of total cholesterol and statin therapy on mortality in ARDS patients: a secondary analysis of the SAILS and HARP-2 trials

por Pienkos, Shaun M., Moore, Andrew R., Guan, Jiazhen, Levitt, Joseph E., Matthay, Michael A., Baron, Rebecca M., Conlon, John, McAuley, Daniel F., O’Kane, Cecilia M., Rogers, Angela J.
Publicado 2023

Mesenchymal stromal cells-derived extracellular vesicles reprogramme macrophages in ARDS models through the miR-181a-5p-PTEN-pSTAT5-SOCS1 axis

por Su, Yue, Silva, Johnatas Dutra, Doherty, Declan, Simpson, David A, Weiss, Daniel J, Rolandsson-Enes, Sara, McAuley, Daniel F, O'Kane, Cecilia M, Brazil, Derek P, Krasnodembskaya, Anna D
Publicado 2023

Aspirin therapy in patients with acute respiratory distress syndrome (ARDS) is associated with reduced intensive care unit mortality: a prospective analysis

por Boyle, Andrew J, Di Gangi, Stefania, Hamid, Umar I, Mottram, Linda-Jayne, McNamee, Lia, White, Griania, Cross, LJ Mark, McNamee, James J, O’Kane, Cecilia M, McAuley, Daniel F
Publicado 2015

Prevalence of phenotypes of acute respiratory distress syndrome in critically ill patients with COVID-19: a prospective observational study

por Sinha, Pratik, Calfee, Carolyn S, Cherian, Shiney, Brealey, David, Cutler, Sean, King, Charles, Killick, Charlotte, Richards, Owen, Cheema, Yusuf, Bailey, Catherine, Reddy, Kiran, Delucchi, Kevin L, Shankar-Hari, Manu, Gordon, Anthony C, Shyamsundar, Murali, O'Kane, Cecilia M, McAuley, Daniel F, Szakmany, Tamas
Publicado 2020

Novel anti-tumour necrosis factor receptor-1 (TNFR1) domain antibody prevents pulmonary inflammation in experimental acute lung injury

por Proudfoot, Alastair, Bayliffe, Andrew, O’Kane, Cecilia M, Wright, Tracey, Serone, Adrian, Bareille, Philippe Jean, Brown, Vanessa, Hamid, Umar I, Chen, Younan, Wilson, Robert, Cordy, Joanna, Morley, Peter, de Wildt, Ruud, Elborn, Stuart, Hind, Matthew, Chilvers, Edwin R, Griffiths, Mark, Summers, Charlotte, McAuley, Daniel Francis
Publicado 2018

Repair of acute respiratory distress syndrome by stromal cell administration (REALIST) trial: A phase 1 trial

por Gorman, Ellen, Shankar-Hari, Manu, Hopkins, Phil, Tunnicliffe, William S., Perkins, Gavin D., Silversides, Jonathan, McGuigan, Peter, Krasnodembskaya, Anna, Jackson, Colette, Boyle, Roisin, McFerran, Jamie, McDowell, Cliona, Campbell, Christina, McFarland, Margaret, Smythe, Jon, Thompson, Jacqui, Williams, Barry, Curley, Gerard, Laffey, John G., Clarke, Mike, McAuley, Daniel F., O'Kane, Cecilia M.
Publicado 2021

Diagnostic accuracy of pulmonary host inflammatory mediators in the exclusion of ventilator-acquired pneumonia

por Hellyer, Thomas P, Conway Morris, Andrew, McAuley, Daniel F, Walsh, Timothy S, Anderson, Niall H, Singh, Suveer, Dark, Paul, Roy, Alistair I, Baudouin, Simon V, Wright, Stephen E, Perkins, Gavin D, Kefala, Kallirroi, Jeffels, Melinda, McMullan, Ronan, O'Kane, Cecilia M, Spencer, Craig, Laha, Shondipon, Robin, Nicole, Gossain, Savita, Gould, Kate, Ruchaud-Sparagano, Marie-Hélène, Scott, Jonathan, Browne, Emma M, MacFarlane, James G, Wiscombe, Sarah, Widdrington, John D, Dimmick, Ian, Laurenson, Ian F, Nauwelaers, Frans, Simpson, A John
Publicado 2014