Extracellular Forms of Aβ and Tau from iPSC Models of Alzheimer’s Disease Disrupt Synaptic Plasticity

por Hu, Neng-Wei, Corbett, Grant T., Moore, Steven, Klyubin, Igor, O’Malley, Tiernan T., Walsh, Dominic M., Livesey, Frederick J., Rowan, Michael J.
Publicado 2018

A highly sensitive novel immunoassay specifically detects low levels of soluble Aβ oligomers in human cerebrospinal fluid

por Yang, Ting, O’Malley, Tiernan T, Kanmert, Daniel, Jerecic, Jasna, Zieske, Lynn R, Zetterberg, Henrik, Hyman, Bradley T, Walsh, Dominic M, Selkoe, Dennis J
Publicado 2015

IgG Conformer's Binding to Amyloidogenic Aggregates

por Phay, Monichan, Welzel, Alfred T., Williams, Angela D., McWilliams-Koeppen, Helen P., Blinder, Veronika, O'Malley, Tiernan T., Solomon, Alan, Walsh, Dominic M., O'Nuallain, Brian
Publicado 2015

mGlu5 receptors and cellular prion protein mediate amyloid-β-facilitated synaptic long-term depression in vivo

por Hu, Neng-Wei, Nicoll, Andrew J., Zhang, Dainan, Mably, Alexandra J., O’Malley, Tiernan, Purro, Silvia A., Terry, Cassandra, Collinge, John, Walsh, Dominic M., Rowan, Michael J.
Publicado 2014

An in vitro paradigm to assess potential anti-Aβ antibodies for Alzheimer’s disease

por Jin, Ming, O’Nuallain, Brian, Hong, Wei, Boyd, Justin, Lagomarsino, Valentina N., O’Malley, Tiernan T., Liu, Wen, Vanderburg, Charles R., Frosch, Matthew P., Young-Pearse, Tracy, Selkoe, Dennis J., Walsh, Dominic M.
Publicado 2018

Amyloid-β nanotubes are associated with prion protein-dependent synaptotoxicity

por Nicoll, Andrew J., Panico, Silvia, Freir, Darragh B., Wright, Daniel, Terry, Cassandra, Risse, Emmanuel, Herron, Caroline E., O’Malley, Tiernan, Wadsworth, Jonathan D. F., Farrow, Mark A., Walsh, Dominic M., Saibil, Helen R., Collinge, John
Publicado 2013

Autoregulated paracellular clearance of amyloid-β across the blood-brain barrier

por Keaney, James, Walsh, Dominic M., O’Malley, Tiernan, Hudson, Natalie, Crosbie, Darragh E., Loftus, Teresa, Sheehan, Florike, McDaid, Jacqueline, Humphries, Marian M., Callanan, John J., Brett, Francesca M., Farrell, Michael A., Humphries, Peter, Campbell, Matthew
Publicado 2015