Induced conformational change in human IL‐4 upon binding of a signal‐neutralizing DARPin

por Obmolova, Galina, Teplyakov, Alexey, Malia, Thomas J., Keough, Edward, Luo, Jinquan, Sweet, Raymond, Jacobs, Steven A., Yi, Fang, Hippensteel, Randi, O'Neil, Karyn T., Gilliland, Gary L.
Publicado 2015

Protein Engineering Strategies for Sustained Glucagon-Like Peptide-1 Receptor–Dependent Control of Glucose Homeostasis

por Picha, Kristen M., Cunningham, Mark R., Drucker, Daniel J., Mathur, Ashok, Ort, Tatiana, Scully, Michael, Soderman, Avery, Spinka-Doms, Tracy, Stojanovic-Susulic, Vedrana, Ann Thomas, Beth, O'Neil, Karyn T.
Publicado 2008

GLP-1 Receptor Activation Inhibits VLDL Production and Reverses Hepatic Steatosis by Decreasing Hepatic Lipogenesis in High-Fat-Fed APOE*3-Leiden Mice

por Parlevliet, Edwin T., Wang, Yanan, Geerling, Janine J., Schröder-Van der Elst, Janny P., Picha, Kristen, O'Neil, Karyn, Stojanovic-Susulic, Vedrana, Ort, Tatiana, Havekes, Louis M., Romijn, Johannes A., Pijl, Hanno, Rensen, Patrick C. N.
Publicado 2012

Centyrin ligands for extrahepatic delivery of siRNA

por Klein, Donna, Goldberg, Shalom, Theile, Christopher S., Dambra, Richard, Haskell, Kathleen, Kuhar, Elise, Lin, Tricia, Parmar, Rubina, Manoharan, Muthiah, Richter, Mark, Wu, Meizhen, Mendrola Zarazowski, Jeannine, Jadhav, Vasant, Maier, Martin A., Sepp-Lorenzino, Laura, O’Neil, Karyn, Dudkin, Vadim
Publicado 2021