Increased Mutability of Staphylococci in Biofilms as a Consequence of Oxidative Stress

por Ryder, Victoria J., Chopra, Ian, O’Neill, Alex J.
Publicado 2012

Population Diversification in Staphylococcus aureus Biofilms May Promote Dissemination and Persistence

por Savage, Victoria J., Chopra, Ian, O’Neill, Alex J.
Publicado 2013

Mutagenesis Mapping of the Protein-Protein Interaction Underlying FusB-Type Fusidic Acid Resistance

por Cox, Georgina, Edwards, Thomas A., O'Neill, Alex J.
Publicado 2013

ABC-F Proteins Mediate Antibiotic Resistance through Ribosomal Protection

por Sharkey, Liam K. R., Edwards, Thomas A., O’Neill, Alex J.
Publicado 2016

Structure of the 70S Ribosome from the Human Pathogen Acinetobacter baumannii in Complex with Clinically Relevant Antibiotics

por Nicholson, David, Edwards, Thomas A., O'Neill, Alex J., Ranson, Neil A.
Publicado 2020

Resistance to antibacterial antifolates in multidrug-resistant Staphylococcus aureus: prevalence estimates and genetic basis

por Kime, Louise, Waring, Tina, Mohamad, Merianne, Mann, Benjamin F, O’Neill, Alex J
Publicado 2023

Silver resistance in Gram-negative bacteria: a dissection of endogenous and exogenous mechanisms

por Randall, Christopher P., Gupta, Arya, Jackson, Nicole, Busse, David, O'Neill, Alex J.
Publicado 2015

An extensively validated whole-cell biosensor for specific, sensitive and high-throughput detection of antibacterial inhibitors targeting cell-wall biosynthesis

por Galarion, Luiza H, Mitchell, Jennifer K, Randall, Christopher P, O’Neill, Alex J
Publicado 2023

A target-protection mechanism of antibiotic resistance at atomic resolution: insights into FusB-type fusidic acid resistance

por Tomlinson, Jennifer H., Thompson, Gary S., Kalverda, Arnout P., Zhuravleva, Anastasia, O’Neill, Alex J.
Publicado 2016

A platform for detecting cross-resistance in antibacterial drug discovery

por Galarion, Luiza H, Mohamad, Merianne, Alzeyadi, Zeyad, Randall, Christopher P, O’Neill, Alex J
Publicado 2021

Acquired Nisin Resistance in Staphylococcus aureus Involves Constitutive Activation of an Intrinsic Peptide Antibiotic Detoxification Module

por Randall, Christopher P., Gupta, Arya, Utley-Drew, Bret, Lee, Siu Yi, Morrison-Williams, Genevieve, O’Neill, Alex J.
Publicado 2018

Transient Silencing of Antibiotic Resistance by Mutation Represents a Significant Potential Source of Unanticipated Therapeutic Failure

por Kime, Louise, Randall, Christopher P., Banda, Frank I., Coll, Francesc, Wright, John, Richardson, Joseph, Empel, Joanna, Parkhill, Julian, O’Neill, Alex J.
Publicado 2019

Sal-type ABC-F proteins: intrinsic and common mediators of pleuromutilin resistance by target protection in staphylococci

por Mohamad, Merianne, Nicholson, David, Saha, Chayan Kumar, Hauryliuk, Vasili, Edwards, Thomas A, Atkinson, Gemma C, Ranson, Neil A, O’Neill, Alex J
Publicado 2022

Revisiting unexploited antibiotics in search of new antibacterial drug candidates: the case of γ-actinorhodin

por Nass, Nada M., Farooque, Sannia, Hind, Charlotte, Wand, Matthew E., Randall, Christopher P., Sutton, J. Mark, Seipke, Ryan F., Rayner, Christopher M., O’Neill, Alex J.
Publicado 2017

1-((2,4-Dichlorophenethyl)Amino)-3-Phenoxypropan-2-ol Kills Pseudomonas aeruginosa through Extensive Membrane Damage

por Defraine, Valerie, Liebens, Veerle, Loos, Evelien, Swings, Toon, Weytjens, Bram, Fierro, Carolina, Marchal, Kathleen, Sharkey, Liam, O’Neill, Alex J., Corbau, Romu, Marchand, Arnaud, Chaltin, Patrick, Fauvart, Maarten, Michiels, Jan
Publicado 2018

6-Arylpyrido[2,3-d]pyrimidines as Novel ATP-Competitive Inhibitors of Bacterial D-Alanine:D-Alanine Ligase

por Škedelj, Veronika, Arsovska, Emilija, Tomašić, Tihomir, Kroflič, Ana, Hodnik, Vesna, Hrast, Martina, Bešter-Rogač, Marija, Anderluh, Gregor, Gobec, Stanislav, Bostock, Julieanne, Chopra, Ian, O'Neill, Alex J., Randall, Christopher, Zega, Anamarija
Publicado 2012

Structural basis of ABCF-mediated resistance to pleuromutilin, lincosamide, and streptogramin A antibiotics in Gram-positive pathogens

por Crowe-McAuliffe, Caillan, Murina, Victoriia, Turnbull, Kathryn Jane, Kasari, Marje, Mohamad, Merianne, Polte, Christine, Takada, Hiraku, Vaitkevicius, Karolis, Johansson, Jörgen, Ignatova, Zoya, Atkinson, Gemma C., O’Neill, Alex J., Hauryliuk, Vasili, Wilson, Daniel N.
Publicado 2021

Epistasis analysis uncovers hidden antibiotic resistance-associated fitness costs hampering the evolution of MRSA

por Yokoyama, Maho, Stevens, Emily, Laabei, Maisem, Bacon, Leann, Heesom, Kate, Bayliss, Sion, Ooi, Nicola, O’Neill, Alex J., Murray, Ewan, Williams, Paul, Lubben, Anneke, Reeksting, Shaun, Meric, Guillaume, Pascoe, Ben, Sheppard, Samuel K., Recker, Mario, Hurst, Laurence D., Massey, Ruth C.
Publicado 2018

Elucidation of the Mode of Action of a New Antibacterial Compound Active against Staphylococcus aureus and Pseudomonas aeruginosa

por Gerits, Evelien, Blommaert, Eline, Lippell, Anna, O’Neill, Alex J., Weytjens, Bram, De Maeyer, Dries, Fierro, Ana Carolina, Marchal, Kathleen, Marchand, Arnaud, Chaltin, Patrick, Spincemaille, Pieter, De Brucker, Katrijn, Thevissen, Karin, Cammue, Bruno P. A., Swings, Toon, Liebens, Veerle, Fauvart, Maarten, Verstraeten, Natalie, Michiels, Jan
Publicado 2016