Dissecting complex traits: recent advances in hypertension genomics

por O'Shaughnessy, Kevin M
Publicado 2009

Genetic Markers Regulating Blood Pressure in Extreme Discordant Sib Pairs

por Yasmin, O’Shaughnessy, Kevin M.
Publicado 2023

Modified HEK cells simulate DCT cells in their sensitivity and response to changes in extracellular K

por Murthy, Meena, O’Shaughnessy, Kevin M.
Publicado 2019

ROMK expression remains unaltered in a mouse model of familial hyperkalemic hypertension caused by the CUL3(Δ403‐459) mutation

por Murthy, Meena, Kurz, Thimo, O'Shaughnessy, Kevin M.
Publicado 2016

WNK signalling pathways in blood pressure regulation

por Murthy, Meena, Kurz, Thimo, O’Shaughnessy, Kevin M.
Publicado 2016

β1-Adrenoreceptor Polymorphisms and Blood Pressure: 49S Variant Increases Plasma Renin But Not Blood Pressure in Hypertensive Patients

por Sandilands, Alastair J, O’Shaughnessy, Kevin M, , Yasmin
Publicado 2019

A Single Amino Acid Substitution Makes WNK4 Susceptible to SB 203580 and SB 202190

por Glover, Mark, Sweeney, Connor, Davis, Bill, O’Shaughnessy, Kevin M
Publicado 2010

Critical role of the SPAK protein kinase CCT domain in controlling blood pressure

por Zhang, Jinwei, Siew, Keith, Macartney, Thomas, O'Shaughnessy, Kevin M., Alessi, Dario R.
Publicado 2015

Targeted disruption of the Kcnj5 gene in the female mouse lowers aldosterone levels

por Hardege, Iris, Long, Lu, Al Maskari, Raya, Figg, Nicola, O’Shaughnessy, Kevin M.
Publicado 2018

Nonadherence to antihypertensive medications amongst patients with uncontrolled hypertension: A retrospective study

por Kulkarni, Spoorthy, Rao, Raunak, Goodman, James Delman Harry, Connolly, Kathleen, O'Shaughnessy, Kevin M.
Publicado 2021

Combinations of Maternal KIR and Fetal HLA-C Genes Influence the Risk of Preeclampsia and Reproductive Success

por Hiby, Susan E., Walker, James J., O'Shaughnessy, Kevin M., Redman, Christopher W.G., Carrington, Mary, Trowsdale, John, Moffett, Ashley
Publicado 2004

Role of the WNK-activated SPAK kinase in regulating blood pressure

por Rafiqi, Fatema H, Zuber, Annie Mercier, Glover, Mark, Richardson, Ciaran, Fleming, Stewart, Jovanović, Sofija, Jovanović, Aleksandar, O'Shaughnessy, Kevin M, Alessi, Dario R
Publicado 2010

Functional characterization of common BCL11B gene desert variants suggests a lymphocyte-mediated association of BCL11B with aortic stiffness

por Maskari, Raya Al, Hardege, Iris, Cleary, Sarah, Figg, Nicki, Li, Ye, Siew, Keith, Khir, Ashraf, Yu, Yong, Liu, Pentao, Wilkinson, Ian, O’Shaughnessy, Kevin, Yasmin
Publicado 2018

A systematic review and meta-analysis of thiazide-induced hyponatraemia: time to reconsider electrolyte monitoring regimens after thiazide initiation?

por Barber, Jennifer, McKeever, Tricia M, McDowell, Sarah E, Clayton, Jennifer A, Ferner, Robin E, Gordon, Richard D, Stowasser, Michael, O'Shaughnessy, Kevin M, Hall, Ian P, Glover, Mark
Publicado 2015

The matrix proteins aggrecan and fibulin-1 play a key role in determining aortic stiffness

por Yasmin, Maskari, Raya Al, McEniery, Carmel M., Cleary, Sarah E., Li, Ye, Siew, Keith, Figg, Nichola L., Khir, Ashraf W., Cockcroft, John R., Wilkinson, Ian B., O’Shaughnessy, Kevin M.
Publicado 2018

Characterisation of the Cullin-3 mutation that causes a severe form of familial hypertension and hyperkalaemia

por Schumacher, Frances-Rose, Siew, Keith, Zhang, Jinwei, Johnson, Clare, Wood, Nicola, Cleary, Sarah E, Al Maskari, Raya S, Ferryman, James T, Hardege, Iris, Figg, Nichola L, Enchev, Radoslav, Knebel, Axel, O’Shaughnessy, Kevin M, Kurz, Thimo
Publicado 2015

Detection of mutations in KLHL3 and CUL3 in families with FHHt (familial hyperkalaemic hypertension or Gordon's syndrome)

por Glover, Mark, Ware, James S., Henry, Amanda, Wolley, Martin, Walsh, Roddy, Wain, Louise V., Xu, Shengxin, Van’t Hoff, William G., Tobin, Martin D., Hall, Ian P., Cook, Stuart, Gordon, Richard D., Stowasser, Michael, O’Shaughnessy, Kevin M.
Publicado 2014

Phenotypic and pharmacogenetic evaluation of patients with thiazide-induced hyponatremia

por Ware, James S., Wain, Louise V., Channavajjhala, Sarath K., Jackson, Victoria E., Edwards, Elizabeth, Lu, Run, Siew, Keith, Jia, Wenjing, Shrine, Nick, Kinnear, Sue, Jalland, Mahli, Henry, Amanda P., Clayton, Jenny, O’Shaughnessy, Kevin M., Tobin, Martin D., Schuster, Victor L., Cook, Stuart, Hall, Ian P., Glover, Mark
Publicado 2017