Structure of the Catalytic Region of DNA Ligase IV in Complex with an Artemis Fragment Sheds Light on Double-Strand Break Repair

por Ochi, Takashi, Gu, Xiaolong, Blundell, Tom L.
Publicado 2013

The spatial organization of non-homologous end joining: From bridging to end joining

por Ochi, Takashi, Wu, Qian, Blundell, Tom L.
Publicado 2014

The Safety and Effectiveness of Low-Dose Recombinant Tissue Plasminogen Activator (0.6 mg/kg) Therapy for Elderly Acute Ischemic Stroke Patients (≥ 80 Years Old) in the Pre-endovas...

por TAKAYANAGI, Shunsaku, OCHI, Takashi, HANAKITA, Shunya, SUZUKI, Yasutaka, MAEDA, Keiichiro
Publicado 2014

Coil Embolization of VA-PICA Aneurysm Presenting with Hemifacial Spasm with Assistance of Abnormal Muscle Response Monitoring

por Arisawa, Kei, Ochi, Takashi, Goto, Yoshiaki, Nanbu, Syohei, Shojima, Masaaki, Maeda, Keiichiro
Publicado 2020

Structural Biology of DNA Repair: Spatial Organisation of the Multicomponent Complexes of Nonhomologous End Joining

por Ochi, Takashi, Sibanda, Bancinyane Lynn, Wu, Qian, Chirgadze, Dimitri Y., Bolanos-Garcia, Victor M., Blundell, Tom L.
Publicado 2010

Structural Insights into the Role of Domain Flexibility in Human DNA Ligase IV

por Ochi, Takashi, Wu, Qian, Chirgadze, Dimitri Y., Grossmann, J. Günter, Bolanos-Garcia, Victor M., Blundell, Tom L.
Publicado 2012

Different DNA End Configurations Dictate Which NHEJ Components Are Most Important for Joining Efficiency

por Chang, Howard H. Y., Watanabe, Go, Gerodimos, Christina A., Ochi, Takashi, Blundell, Tom L., Jackson, Stephen P., Lieber, Michael R.
Publicado 2016

Structure of BRCA1-BRCT/Abraxas Complex Reveals Phosphorylation-Dependent BRCT Dimerization at DNA Damage Sites

por Wu, Qian, Paul, Atanu, Su, Dan, Mehmood, Shahid, Foo, Tzeh Keong, Ochi, Takashi, Bunting, Emma L., Xia, Bing, Robinson, Carol V., Wang, Bin, Blundell, Tom L.
Publicado 2016

Catalytically inactive DNA ligase IV promotes DNA repair in living cells

por Goff, Noah J, Brenière, Manon, Buehl, Christopher J, de Melo, Abinadabe J, Huskova, Hana, Ochi, Takashi, Blundell, Tom L, Mao, Weifeng, Yu, Kefei, Modesti, Mauro, Meek, Katheryn
Publicado 2022

Dissection of DNA double-strand break repair using novel single-molecule forceps

por Wang, Jing L., Duboc, Camille, Wu, Qian, Ochi, Takashi, Liang, Shikang, Tsutakawa, Susan E., Lees-Miller, Susan P., Nadal, Marc, Tainer, John A., Blundell, Tom L., Strick, Terence R.
Publicado 2018

Gene Signature–Based Approach Identified MEK1/2 as a Potential Target Associated With Relapse After Anti-TNFα Treatment for Crohn’s Disease

por Gamo, Kanae, Okuzono, Yuumi, Yabuki, Masato, Ochi, Takashi, Sugimura, Kyoko, Sato, Yosuke, Sagara, Masaki, Hayashi, Hiroki, Ishimura, Yoshimasa, Nishimoto, Yutaka, Murakawa, Yusuke, Shiokawa, Zenyu, Gotoh, Masayuki, Miyazaki, Takahiro, Ebisuno, Yukihiko
Publicado 2018

CCDC61/VFL3 Is a Paralog of SAS6 and Promotes Ciliary Functions

por Ochi, Takashi, Quarantotti, Valentina, Lin, Huawen, Jullien, Jerome, Rosa e Silva, Ivan, Boselli, Francesco, Barnabas, Deepak D., Johnson, Christopher M., McLaughlin, Stephen H., Freund, Stefan M.V., Blackford, Andrew N., Kimata, Yuu, Goldstein, Raymond E., Jackson, Stephen P., Blundell, Tom L., Dutcher, Susan K., Gergely, Fanni, van Breugel, Mark
Publicado 2020