Immune Checkpoint Inhibitors for the Treatment of Unresectable Stage III Non–Small Cell Lung Cancer: Emerging Mechanisms and Perspectives

por Inoue, Hiroyuki, Okamoto, Isamu
Publicado 2019

Molecularly targeted approaches herald a new era of non-small-cell lung cancer treatment

por Kaneda, Hiroyasu, Yoshida, Takeshi, Okamoto, Isamu
Publicado 2013

Survival Outcome Assessed According to Tumor Response and Shrinkage Pattern in Patients with EGFR Mutation–Positive Non–Small-Cell Lung Cancer Treated with Gefitinib or Erlotinib...

por Takeda, Masayuki, Okamoto, Isamu, Nakagawa, Kazuhiko
Publicado 2014

Clinical development of nintedanib for advanced non-small-cell lung cancer

por Takeda, Masayuki, Okamoto, Isamu, Nakagawa, Kazuhiko
Publicado 2015

Scedosporium apiospermum lung disease in a patient with nontuberculous mycobacteria

por Ogata, Hiroaki, Harada, Eiji, Okamoto, Isamu
Publicado 2020

Allergic bronchopulmonary aspergillosis manifested secondary to bacterial pleural empyema

por Kawano, Hiromu, Kan‐o, Keiko, Egashira, Ayaka, Okamoto, Isamu
Publicado 2023

Phase II Study of Nivolumab Plus Ipilimumab with Platinum-Based Chemotherapy for Treatment-Naïve Advanced Non-Small Cell Lung Cancer with Untreated Brain Metastases: NIke Trial (LO...

por Tsuchiya-Kawano, Yuko, Shiraishi, Yoshimasa, Kiyomi, Fumiaki, Okamoto, Isamu
Publicado 2021

Human Ect2 Is an Exchange Factor for Rho Gtpases, Phosphorylated in G2/M Phases, and Involved in Cytokinesis

por Tatsumoto, Takashi, Xie, Xiaozhen, Blumenthal, Rayah, Okamoto, Isamu, Miki, Toru
Publicado 1999

Impact of treatment with bevacizumab beyond disease progression: a randomized phase II study of docetaxel with or without bevacizumab after platinum-based chemotherapy plus bevaciz...

por Takeda, Masayuki, Okamoto, Isamu, Yamanaka, Takeharu, Nakagawa, Kazuhiko, Nakanishi, Yoichi
Publicado 2012

Development of anaplastic lymphoma kinase (ALK) inhibitors and molecular diagnosis in ALK rearrangement-positive lung cancer

por Iwama, Eiji, Okamoto, Isamu, Harada, Taishi, Takayama, Koichi, Nakanishi, Yoichi
Publicado 2014

Multiple regulatory mechanisms of hepatocyte growth factor expression in malignant cells with a short poly(dA) sequence in the HGF gene promoter

por SAKAI, KAZUKO, TAKEDA, MASAYUKI, OKAMOTO, ISAMU, NAKAGAWA, KAZUHIKO, NISHIO, KAZUTO
Publicado 2015

Pleuroparenchymal fibroelastosis secondary to autologous peripheral blood stem cell transplantation: A case report

por Egashira, Ayaka, Yoneshima, Yasuto, Mizusaki, Shun, Tsuneoka, Yuki, Tsubouchi, Kazuya, Okamoto, Isamu
Publicado 2023

Targeting MET Amplification as a New Oncogenic Driver

por Kawakami, Hisato, Okamoto, Isamu, Okamoto, Wataru, Tanizaki, Junko, Nakagawa, Kazuhiko, Nishio, Kazuto
Publicado 2014

First-line afatinib for the treatment of EGFR mutation-positive non-small-cell lung cancer in the ‘real-world’ clinical setting

por Park, Keunchil, Wan-Teck Lim, Darren, Okamoto, Isamu, Yang, James Chih-Hsin
Publicado 2019

Phase II study of carboplatin/nab-paclitaxel/atezolizumab combination therapy for advanced nonsquamous non–small cell lung cancer patients with impaired renal function: RESTART tri...

por Shiraishi, Yoshimasa, Kishimoto, Junji, Shimose, Takayuki, Toi, Yukihiro, Sugawara, Shunichi, Okamoto, Isamu
Publicado 2022

Metastatic Lung Adenocarcinoma Mimicking Meningioma

por Yanagihara, Toyoshi, Seki, Nanae, Hiwatashi, Akio, Arimura, Koichi, O Suzuki, Satoshi, Okamoto, Isamu
Publicado 2017

Phase I Clinical and Pharmacokinetic Study of RAD001 (Everolimus) Administered Daily to Japanese Patients with Advanced Solid Tumors

por Okamoto, Isamu, Doi, Toshihiko, Ohtsu, Atsushi, Miyazaki, Masaki, Tsuya, Asuka, Kurei, Katsutoshi, Kobayashi, Ken, Nakagawa, Kazuhiko
Publicado 2010

Visualization and quantitation of epidermal growth factor receptor homodimerization and activation with a proximity ligation assay

por Ota, Keiichi, Harada, Taishi, Otsubo, Kohei, Fujii, Akiko, Tsuchiya, Yuko, Tanaka, Kentaro, Okamoto, Isamu, Nakanishi, Yoichi
Publicado 2017

Durable response to nivolumab in a lung adenocarcinoma patient with idiopathic pulmonary fibrosis

por Ide, Maako, Tanaka, Kentaro, Sunami, Shunya, Asoh, Tatsuma, Maeyama, Takashige, Tsuruta, Nobuko, Nakanishi, Yoichi, Okamoto, Isamu
Publicado 2018

Sensitivity of epidermal growth factor receptor with single or double uncommon mutations to afatinib confirmed by a visual assay

por Kimura, Shinichi, Tanaka, Kentaro, Harada, Taishi, Liu, Renpeng, Shibahara, Daisuke, Kawano, Yuko, Nakanishi, Yoichi, Okamoto, Isamu
Publicado 2018