High bone mass in mice can be linked to lower osteoclast formation, resorptive capacity, and restricted in vitro sensitivity to inhibition by stable sulforaphane

por Louka, Polymnia, Orriss, Isabel R., Pitsillides, Andrew A.
Publicado 2022

Allopurinol and oxypurinol promote osteoblast differentiation and increase bone formation

por Orriss, Isabel R., Arnett, Timothy R., George, Jacob, Witham, Miles D.
Publicado 2016

Modulation of osteoblast differentiation and function by the P2X4 receptor

por Orriss, Isabel R., Davies, Bethan K., Bourne, Lucie E., Arnett, Timothy R.
Publicado 2022

Extracellular ATP Released by Osteoblasts Is A Key Local Inhibitor of Bone Mineralisation

por Orriss, Isabel R., Key, Michelle L., Hajjawi, Mark O. R., Arnett, Timothy R.
Publicado 2013

Extracellular Nucleotides Regulate Arterial Calcification by Activating Both Independent and Dependent Purinergic Receptor Signaling Pathways

por Opdebeeck, Britt, Orriss, Isabel R., Neven, Ellen, D’Haese, Patrick C., Verhulst, Anja
Publicado 2020

The P2X7 Receptor is an Important Regulator of Extracellular ATP Levels

por Brandao-Burch, Andrea, Key, Michelle L., Patel, Jessal J., Arnett, Timothy R., Orriss, Isabel R.
Publicado 2012

Optimisation of the differing conditions required for bone formation in vitro by primary osteoblasts from mice and rats

por ORRISS, ISABEL R., HAJJAWI, MARK O.R., HUESA, CARMEN, MACRAE, VICKY E., ARNETT, TIMOTHY R.
Publicado 2014

Acidosis Is a key regulator of osteoblast ecto‐nucleotidase pyrophosphatase/phosphodiesterase 1 (NPP1) expression and activity

por Orriss, Isabel R., Key, Michelle L., Hajjawi, Mark O.R., Millán, José L., Arnett, Timothy R.
Publicado 2015

The in vitro behaviour of canine osteoblasts derived from different bone types

por Meeson, Richard L., Perpétuo, Inês P., Parsons, Kevin, Orriss, Isabel R., Shah, Mittal, Pitsillides, Andrew A., Doube, Michael
Publicado 2019

Mineralisation of collagen rich soft tissues and osteocyte lacunae in Enpp1(−/−) mice

por Hajjawi, Mark O.R., MacRae, Vicky E., Huesa, Carmen, Boyde, Alan, Millán, José Luis, Arnett, Timothy R., Orriss, Isabel R.
Publicado 2014

Spina bifida-predisposing heterozygous mutations in Planar Cell Polarity genes and Zic2 reduce bone mass in young mice

por Orriss, Isabel R., Lanham, Stuart, Savery, Dawn, Greene, Nicholas D. E., Stanier, Philip, Oreffo, Richard, Copp, Andrew J., Galea, Gabriel L.
Publicado 2018

A Machine Learning-Based Image Segmentation Method to Quantify In Vitro Osteoclast Culture Endpoints

por Davies, Bethan K., Hibbert, Andrew P., Roberts, Scott J., Roberts, Helen C., Tickner, Jennifer C., Holdsworth, Gill, Arnett, Timothy R., Orriss, Isabel R.
Publicado 2023

Differing calcification processes in cultured vascular smooth muscle cells and osteoblasts

por Patel, Jessal J., Bourne, Lucie E., Davies, Bethan K., Arnett, Timothy R., MacRae, Vicky E., Wheeler-Jones, Caroline PD., Orriss, Isabel R.
Publicado 2019

Stable sulforaphane protects against gait anomalies and modifies bone microarchitecture in the spontaneous STR/Ort model of osteoarthritis

por Javaheri, Behzad, Poulet, Blandine, Aljazzar, Ahmed, de Souza, Roberto, Piles, Miriam, Hopkinson, Mark, Shervill, Elaine, Pollard, Andrea, Chan, Boris, Chang, Yu-Mei, Orriss, Isabel R., Lee, Peter D., Pitsillides, Andrew A.
Publicado 2017