Proto-oncogene CT10-regulated kinase (CRK) is a pro-apoptotic transducer of endoplasmic reticulum stress

por Austgen, Kathryn, Johnson, Emily T., Park, Tae-Ju, Curran, Tom, Oakes, Scott A.
Publicado 2011

DISSECTING TUMOR TRANSCRIPTIONAL HETEROGENEITY FROM SINGLE-CELL RNA-SEQ DATA BY GENERALIZED BINARY COVARIANCE DECOMPOSITION

por Liu, Yusha, Carbonetto, Peter, Willwerscheid, Jason, Oakes, Scott A., Macleod, Kay F., Stephens, Matthew
Publicado 2023

Deletion of the Unfolded Protein Response Transducer IRE1α Is Detrimental to Aging Photoreceptors and to ER Stress-Mediated Retinal Degeneration

por Massoudi, Dawiyat, Gorman, Seán, Kuo, Yien-Ming, Iwawaki, Takao, Oakes, Scott A., Papa, Feroz R., Gould, Douglas B.
Publicado 2023

Golgi fragmentation precedes neuromuscular denervation and is associated with endosome abnormalities in SOD1-ALS mouse motor neurons

por van Dis, Vera, Kuijpers, Marijn, Haasdijk, Elize D, Teuling, Eva, Oakes, Scott A, Hoogenraad, Casper C, Jaarsma, Dick
Publicado 2014

Acute Recurrent Pancreatitis in a Child With INS-Related Monogenic Diabetes and a Heterozygous Pathogenic CFTR Mutation

por Son, Rachel G, Kandasamy, Balamurugan, Bowden, Tiana, Azzam, Ruba K, Oakes, Scott A, Philipson, Louis H, Greeley, Siri Atma W
Publicado 2022

CDK1 Inhibition Targets the p53-NOXA-MCL1 Axis, Selectively Kills Embryonic Stem Cells, and Prevents Teratoma Formation

por Huskey, Noelle E., Guo, Tingxia, Evason, Kimberley J., Momcilovic, Olga, Pardo, David, Creasman, Katelyn J., Judson, Robert L., Blelloch, Robert, Oakes, Scott A., Hebrok, Matthias, Goga, Andrei
Publicado 2015

Divergent allosteric control of the IRE1α endoribonuclease using kinase inhibitors

por Wang, Likun, Perera, B. Gayani K., Hari, Sanjay B., Bhhatarai, Barun, Backes, Bradley J., Seeliger, Markus A., Schürer, Stephan C., Oakes, Scott A., Papa, Feroz R., Maly, Dustin J.
Publicado 2012

Cannabidiol Inhibits SARS-CoV-2 Replication and Promotes the Host Innate Immune Response

por Nguyen, Long Chi, Yang, Dongbo, Nicolaescu, Vlad, Best, Thomas J., Ohtsuki, Takashi, Chen, Shao-Nong, Friesen, J. Brent, Drayman, Nir, Mohamed, Adil, Dann, Christopher, Silva, Diane, Gula, Haley, Jones, Krysten A., Millis, J. Michael, Dickinson, Bryan C., Tay, Savaş, Oakes, Scott A., Pauli, Guido F., Meltzer, David O., Randall, Glenn, Rosner, Marsha Rich
Publicado 2021

SARS-CoV-2 diverges from other betacoronaviruses in only partially activating the IRE1α/XBP1 ER stress pathway in human lung-derived cells

por Nguyen, Long C., Renner, David M., Silva, Diane, Yang, Dongbo, Parenti, Nicholas, Medina, Kaeri M., Nicolaescu, Vlad, Gula, Haley, Drayman, Nir, Valdespino, Andrea, Mohamed, Adil, Dann, Christopher, Wannemo, Kristin, Robinson-Mailman, Lydia, Gonzalez, Alan, Stock, Letícia, Cao, Mengrui, Qiao, Zeyu, Moellering, Raymond E., Tay, Savas, Randall, Glenn, Beers, Michael F., Rosner, Marsha Rich, Oakes, Scott A., Weiss, Susan R.
Publicado 2022

SARS-CoV-2 Diverges from Other Betacoronaviruses in Only Partially Activating the IRE1α/XBP1 Endoplasmic Reticulum Stress Pathway in Human Lung-Derived Cells

por Nguyen, Long C., Renner, David M., Silva, Diane, Yang, Dongbo, Parenti, Nicholas A., Medina, Kaeri M., Nicolaescu, Vlad, Gula, Haley, Drayman, Nir, Valdespino, Andrea, Mohamed, Adil, Dann, Christopher, Wannemo, Kristin, Robinson-Mailman, Lydia, Gonzalez, Alan, Stock, Letícia, Cao, Mengrui, Qiao, Zeyu, Moellering, Raymond E., Tay, Savas, Randall, Glenn, Beers, Michael F., Rosner, Marsha Rich, Oakes, Scott A., Weiss, Susan R.
Publicado 2022

The E3 ligase TRIM1 ubiquitinates LRRK2 and controls its localization, degradation, and toxicity

por Stormo, Adrienne E.D., Shavarebi, Farbod, FitzGibbon, Molly, Earley, Elizabeth M., Ahrendt, Hannah, Lum, Lotus S., Verschueren, Erik, Swaney, Danielle L., Skibinski, Gaia, Ravisankar, Abinaya, van Haren, Jeffrey, Davis, Emily J., Johnson, Jeffrey R., Von Dollen, John, Balen, Carson, Porath, Jacob, Crosio, Claudia, Mirescu, Christian, Iaccarino, Ciro, Dauer, William T., Nichols, R. Jeremy, Wittmann, Torsten, Cox, Timothy C., Finkbeiner, Steve, Krogan, Nevan J., Oakes, Scott A., Hiniker, Annie
Publicado 2022