Mapping the Spatial Distribution of Fibrillar Polymorphs in Human Brain Tissue

por Bashit, Abdullah Al, Nepal, Prakash, Connors, Theresa, Oakley, Derek H., Hyman, Bradley T., Yang, Lin, Makowski, Lee
Publicado 2022

The role of microglia in processing and spreading of bioactive tau seeds in Alzheimer’s disease

por Hopp, Sarah C., Lin, Yang, Oakley, Derek, Roe, Allyson D., DeVos, Sarah L., Hanlon, David, Hyman, Bradley T.
Publicado 2018

Continuous Monitoring of Tau-Induced Neurotoxicity in Patient-Derived iPSC-Neurons

por Oakley, Derek H., Klickstein, Naomi, Commins, Caitlin, Chung, Mirra, Dujardin, Simon, Bennett, Rachel E., Hyman, Bradley T., Frosch, Matthew P.
Publicado 2021

Kinetics of tau aggregation reveals patient-specific tau characteristics among Alzheimer’s cases

por Kamath, Tarun V, Klickstein, Naomi, Commins, Caitlin, Fernandes, Analiese R, Oakley, Derek H, Frosch, Matthew P, Hyman, Bradley T, Dujardin, Simon
Publicado 2021

A correlation map of genome-wide DNA methylation patterns between paired human brain and buccal samples

por Sommerer, Yasmine, Ohlei, Olena, Dobricic, Valerija, Oakley, Derek H., Wesse, Tanja, Sedghpour Sabet, Sanaz, Demuth, Ilja, Franke, Andre, Hyman, Bradley T., Lill, Christina M., Bertram, Lars
Publicado 2022

Dimensional clinical phenotyping using post‐mortem brain donor medical records: post‐mortem RDoC profiling is associated with Alzheimer's disease neuropathology

por Vogelgsang, Jonathan, Dan, Shu, Lally, Anna P., Chatigny, Michael, Vempati, Sangeetha, Abston, Joshua, Durning, Peter T., Oakley, Derek H., McCoy, Thomas H., Klengel, Torsten, Berretta, Sabina
Publicado 2023

Synaptic Tau Seeding Precedes Tau Pathology in Human Alzheimer's Disease Brain

por DeVos, Sarah L., Corjuc, Bianca T., Oakley, Derek H., Nobuhara, Chloe K., Bannon, Riley N., Chase, Alison, Commins, Caitlin, Gonzalez, Jose A., Dooley, Patrick M., Frosch, Matthew P., Hyman, Bradley T.
Publicado 2018

Common mouse models of tauopathy reflect early but not late human disease

por Wenger, Kathrin, Viode, Arthur, Schlaffner, Christoph N., van Zalm, Patrick, Cheng, Long, Dellovade, Tammy, Langlois, Xavier, Bannon, Anthony, Chang, Rui, Connors, Theresa R., Oakley, Derek, Renard, Bernhard, Rappsilber, Juri, Hyman, Bradley, Steen, Hanno, Steen, Judith A.
Publicado 2023

Plasma biomarkers for diagnosis of Alzheimer's disease and prediction of cognitive decline in individuals with mild cognitive impairment

por Kivisäkk, Pia, Carlyle, Becky C., Sweeney, Thadryan, Trombetta, Bianca A., LaCasse, Kathryn, El-Mufti, Leena, Tuncali, Idil, Chibnik, Lori B., Das, Sudeshna, Scherzer, Clemens R., Johnson, Keith A., Dickerson, Bradford C., Gomez-Isla, Teresa, Blacker, Deborah, Oakley, Derek H., Frosch, Matthew P., Hyman, Bradley T., Aghvanyan, Anahit, Bathala, Pradeepthi, Campbell, Christopher, Sigal, George, Stengelin, Martin, Arnold, Steven E.
Publicado 2023

Novel genetic variants in MAPT and alterations in tau phosphorylation in amyotrophic lateral sclerosis post‐mortem motor cortex and cerebrospinal fluid

por Petrozziello, Tiziana, Amaral, Ana C., Dujardin, Simon, Farhan, Sali M. K., Chan, James, Trombetta, Bianca A., Kivisäkk, Pia, Mills, Alexandra N., Bordt, Evan A., Kim, Spencer E., Dooley, Patrick M., Commins, Caitlin, Connors, Theresa R., Oakley, Derek H., Ghosal, Anubrata, Gomez‐Isla, Teresa, Hyman, Bradley T., Arnold, Steven E., Spires‐Jones, Tara, Cudkowicz, Merit E., Berry, James D., Sadri‐Vakili, Ghazaleh
Publicado 2021

Clinical Trial-Ready Patient Cohorts for Multiple System Atrophy: Coupling Biospecimen and iPSC Banking to Longitudinal Deep-Phenotyping

por Ndayisaba, Alain, Pitaro, Ariana T., Willett, Andrew S., Jones, Kristie A., de Gusmao, Claudio Melo, Olsen, Abby L., Kim, Jisoo, Rissanen, Eero, Woods, Jared K., Srinivasan, Sharan R., Nagy, Anna, Nagy, Amanda, Mesidor, Merlyne, Cicero, Steven, Patel, Viharkumar, Oakley, Derek H., Tuncali, Idil, Taglieri-Noble, Katherine, Clark, Emily C., Paulson, Jordan, Krolewski, Richard C., Ho, Gary P., Hung, Albert Y., Wills, Anne-Marie, Hayes, Michael T., Macmore, Jason P., Warren, Luigi, Bower, Pamela G., Langer, Carol B., Kellerman, Lawrence R., Humphreys, Christopher W., Glanz, Bonnie I., Dielubanza, Elodi J., Frosch, Matthew P., Freeman, Roy L., Gibbons, Christopher H., Stefanova, Nadia, Chitnis, Tanuja, Weiner, Howard L., Scherzer, Clemens R., Scholz, Sonja W., Vuzman, Dana, Cox, Laura M., Wenning, Gregor, Schmahmann, Jeremy D., Gupta, Anoopum S., Novak, Peter, Young, Geoffrey S., Feany, Mel B., Singhal, Tarun, Khurana, Vikram
Publicado 2022

Creating the Pick’s disease International Consortium: Association study of MAPT H2 haplotype with risk of Pick’s disease

por Valentino, Rebecca R, Scotton, William J, Roemer, Shanu F, Lashley, Tammaryn, Heckman, Michael G, Shoai, Maryam, Martinez-Carrasco, Alejandro, Tamvaka, Nicole, Walton, Ronald L, Baker, Matthew C, Macpherson, Hannah L, Real, Raquel, Soto-Beasley, Alexandra I, Mok, Kin, Revesz, Tamas, Warner, Thomas T, Jaunmuktane, Zane, Boeve, Bradley F, Christopher, Elizabeth A, DeTure, Michael, Duara, Ranjan, Graff-Radford, Neill R, Josephs, Keith A, Knopman, David S, Koga, Shunsuke, Murray, Melissa E, Lyons, Kelly E, Pahwa, Rajesh, Parisi, Joseph E, Petersen, Ronald C, Whitwell, Jennifer, Grinberg, Lea T, Miller, Bruce, Schlereth, Athena, Seeley, William W, Spina, Salvatore, Grossman, Murray, Irwin, David J, Lee, Edward B, Suh, EunRan, Trojanowski, John Q, Van Deerlin, Vivianna M, Wolk, David A, Connors, Theresa R, Dooley, Patrick M, Frosch, Matthew P, Oakley, Derek H, Aldecoa, Iban, Balasa, Mircea, Gelpi, Ellen, Borrego-Écija, Sergi, de Eugenio Huélamo, Rosa Maria, Gascon-Bayarri, Jordi, Sánchez-Valle, Raquel, Sanz-Cartagena, Pilar, Piñol-Ripoll, Gerard, Molina-Porcel, Laura, Bigio, Eileen H, Flanagan, Margaret E, Gefen, Tamar, Rogalski, Emily J, Weintraub, Sandra, Redding-Ochoa, Javier, Chang, Koping, Troncoso, Juan C, Prokop, Stefan, Newell, Kathy L, Ghetti, Bernardino, Jones, Matthew, Richardson, Anna, Robinson, Andrew C, Roncaroli, Federico, Snowden, Julie, Allinson, Kieren, Green, Oliver, Rowe, James B, Singh, Poonam, Beach, Thomas G, Serrano, Geidy E, Flowers, Xena E, Goldman, James E, Heaps, Allison C, Leskinen, Sandra P, Teich, Andrew F, Black, Sandra E, Keith, Julia L, Masellis, Mario, Bodi, Istvan, King, Andrew, Sarraj, Safa-Al, Troakes, Claire, Halliday, Glenda M, Hodges, John R, Kril, Jillian J, Kwok, John B, Piguet, Olivier, Gearing, Marla, Arzberger, Thomas, Roeber, Sigrun, Attems, Johannes, Morris, Christopher M, Thomas, Alan J, Evers, Bret M., White, Charles L, Mechawar, Naguib, Sieben, Anne A, Cras, Patrick P, De Vil, Bart B, De Deyn, Peter Paul P.P., Duyckaerts, Charles, Le Ber, Isabelle, Seihean, Danielle, Turbant-Leclere, Sabrina, MacKenzie, Ian R, McLean, Catriona, Cykowski, Matthew D, Ervin, John F, Wang, Shih-Hsiu J, Graff, Caroline, Nennesmo, Inger, Nagra, Rashed M, Riehl, James, Kovacs, Gabor G, Giaccone, Giorgio, Nacmias, Benedetta, Neumann, Manuela, Ang, Lee-Cyn, Finger, Elizabeth C, Blauwendraat, Cornelis, Nalls, Mike A, Singleton, Andrew B, Vitale, Dan, Cunha, Cristina, Carvalho, Agostinho, Wszolek, Zbigniew K, Morris, Huw R, Rademakers, Rosa, Hardy, John A, Dickson, Dennis W, Rohrer, Jonathan D, Ross, Owen A
Publicado 2023