Comprehensive Search for GPCR Compounds which Can Enhance MafA and/or PDX-1 Expression Levels Using a Small Molecule Compound Library

por Kaneto, Hideaki, Obata, Atsushi, Shimoda, Masashi, Kimura, Tomohiko, Obata, Yoshiyuki, Ikeda, Tomoko, Moriuchi, Saeko, Nakanishi, Shuhei, Mune, Tomoatsu, Kaku, Kohei
Publicado 2023

Dulaglutide exerts beneficial anti atherosclerotic effects in ApoE knockout mice with diabetes: the earlier, the better

por Sanada, Junpei, Obata, Atsushi, Obata, Yoshiyuki, Fushimi, Yoshiro, Shimoda, Masashi, Kohara, Kenji, Nakanishi, Shuhei, Mune, Tomoatsu, Kaku, Kohei, Kaneto, Hideaki
Publicado 2021

Early combination therapy of empagliflozin and linagliptin exerts beneficial effects on pancreatic β cells in diabetic db/db mice

por Fushimi, Yoshiro, Obata, Atsushi, Sanada, Junpei, Nogami, Yuka, Ikeda, Tomoko, Yamasaki, Yuki, Obata, Yoshiyuki, Shimoda, Masashi, Nakanishi, Shuhei, Mune, Tomoatsu, Kaku, Kohei, Kaneto, Hideaki
Publicado 2021

Vascular endothelial PDPK1 plays a pivotal role in the maintenance of pancreatic beta cell mass and function in adult male mice

por Obata, Atsushi, Kimura, Tomohiko, Obata, Yoshiyuki, Shimoda, Masashi, Kinoshita, Tomoe, Kohara, Kenji, Okauchi, Seizo, Hirukawa, Hidenori, Kamei, Shinji, Nakanishi, Shuhei, Mune, Tomoatsu, Kaku, Kohei, Kaneto, Hideaki
Publicado 2019

Imeglimin exerts favorable effects on pancreatic β-cells by improving morphology in mitochondria and increasing the number of insulin granules

por Sanada, Junpei, Obata, Atsushi, Fushimi, Yoshiro, Kimura, Tomohiko, Shimoda, Masashi, Ikeda, Tomoko, Nogami, Yuka, Obata, Yoshiyuki, Yamasaki, Yuki, Nakanishi, Shuhei, Mune, Tomoatsu, Kaku, Kohei, Kaneto, Hideaki
Publicado 2022