BMI is associated with FEV(1) decline in chronic obstructive pulmonary disease: a meta-analysis of clinical trials

por Sun, Yilan, Milne, Stephen, Jaw, Jen Erh, Yang, Chen Xi, Xu, Feng, Li, Xuan, Obeidat, Ma’en, Sin, Don D.
Publicado 2019

Total particulate matter concentration skews cigarette smoke's gene expression profile

por Dvorkin-Gheva, Anna, Vanderstocken, Gilles, Yildirim, Ali Önder, Brandsma, Corry-Anke, Obeidat, Ma'en, Bossé, Yohan, Hassell, John A., Stampfli, Martin R.
Publicado 2016

Effect of short-term oral prednisone therapy on blood gene expression: a randomised controlled clinical trial

por Takiguchi, Hiroto, Chen, Virginia, Obeidat, Ma’en, Hollander, Zsuzsanna, FitzGerald, J. Mark, McManus, Bruce M., Ng, Raymond T., Sin, Don D.
Publicado 2019

Impact of Statins on Gene Expression in Human Lung Tissues

por Lane, Jérôme, van Eeden, Stephan F., Obeidat, Ma’en, Sin, Don D., Tebbutt, Scott J., Timens, Wim, Postma, Dirkje S., Laviolette, Michel, Paré, Peter D., Bossé, Yohan
Publicado 2015

The genetics of smoking in individuals with chronic obstructive pulmonary disease

por Obeidat, Ma’en, Zhou, Guohai, Li, Xuan, Hansel, Nadia N., Rafaels, Nicholas, Mathias, Rasika, Ruczinski, Ingo, Beaty, Terri H., Barnes, Kathleen C., Paré, Peter D., Sin, Don D.
Publicado 2018

The Effect of Statins on Blood Gene Expression in COPD

por Obeidat, Ma’en, Fishbane, Nick, Nie, Yunlong, Chen, Virginia, Hollander, Zsuzsanna, Tebbutt, Scott J., Bossé, Yohan, Ng, Raymond T., Miller, Bruce E., McManus, Bruce, Rennard, Stephen, Paré, Peter D., Sin, Don D.
Publicado 2015

The Overlap of Lung Tissue Transcriptome of Smoke Exposed Mice with Human Smoking and COPD

por Obeidat, Ma’en, Dvorkin-Gheva, Anna, Li, Xuan, Bossé, Yohan, Brandsma, Corry-Anke, Nickle, David C., Hansbro, Philip M., Faner, Rosa, Agusti, Alvar, Paré, Peter D., Stampfli, Martin R., Sin, Don D.
Publicado 2018

Widespread Sexual Dimorphism in the Transcriptome of Human Airway Epithelium in Response to Smoking

por Yang, Chen Xi, Shi, Henry, Ding, Irving, Milne, Stephen, Hernandez Cordero, Ana I., Yang, Cheng Wei Tony, Kim, Edward Kyoo-Hoon, Hackett, Tillie-Louise, Leung, Janice, Sin, Don D., Obeidat, Ma’en
Publicado 2019

TWIST1 DNA methylation is a cell marker of airway and parenchymal lung fibroblasts that are differentially methylated in asthma

por Clifford, Rachel L., Yang, Chen Xi, Fishbane, Nick, Patel, Jamie, MacIsaac, Julia L., McEwen, Lisa M., May, Sean T., Castellanos-Uribe, Marcos, Nair, Parameswaran, Obeidat, Ma’en, Kobor, Michael S., Knox, Alan J., Hackett, Tillie-Louise
Publicado 2020

Genetic regulation of gene expression of MIF family members in lung tissue

por Florez-Sampedro, Laura, Brandsma, Corry-Anke, de Vries, Maaike, Timens, Wim, Bults, Rene, Vermeulen, Cornelis J., van den Berge, Maarten, Obeidat, Ma’en, Joubert, Philippe, Nickle, David C., Poelarends, Gerrit J., Faiz, Alen, Melgert, Barbro N.
Publicado 2020

Gene expression analysis in asthma using a targeted multiplex array

por Pascoe, Christopher D., Obeidat, Ma’en, Arsenault, Bryna A., Nie, Yunlong, Warner, Stephanie, Stefanowicz, Dorota, Wadsworth, Samuel J., Hirota, Jeremy A., Jasemine Yang, S., Dorscheid, Delbert R., Carlsten, Chris, Hackett, Tillie L., Seow, Chun Y., Paré, Peter D.
Publicado 2017

Responsiveness to Ipratropium Bromide in Male and Female Patients with Mild to Moderate Chronic Obstructive Pulmonary Disease

por Li, Xuan, Obeidat, Ma'en, Zhou, Guohai, Leung, Janice M., Tashkin, Donald, Wise, Robert, Connett, John, Joubert, Philippe, Bossé, Yohan, van den Berge, Maarten, Brandsma, Corry-Anke, Nickle, David C., Hao, Ke, Paré, Peter D., Sin, Don D.
Publicado 2017

Network-based analysis reveals novel gene signatures in peripheral blood of patients with chronic obstructive pulmonary disease

por Obeidat, Ma’en, Nie, Yunlong, Chen, Virginia, Shannon, Casey P., Andiappan, Anand Kumar, Lee, Bernett, Rotzschke, Olaf, Castaldi, Peter J., Hersh, Craig P., Fishbane, Nick, Ng, Raymond T., McManus, Bruce, Miller, Bruce E., Rennard, Stephen, Paré, Peter D., Sin, Don D.
Publicado 2017

Genes related to emphysema are enriched for ubiquitination pathways

por Stepaniants, Sergey, Wang, I-Ming, Boie, Yves, Mortimer, James, Kennedy, Brian, Elliott, Mark, Hayashi, Shizu, Luo, Honglin, Wong, Jerry, Loy, Leanna, Coulter, Silvija, Roberts, Christopher J, Hogg, James C, Sin, Don D, O’Neill, Gary, Crackower, Michael, Morris, Melody, Paré, Peter D, Obeidat, Ma’en
Publicado 2014

GSTCD and INTS12 Regulation and Expression in the Human Lung

por Obeidat, Ma’en, Miller, Suzanne, Probert, Kelly, Billington, Charlotte K., Henry, Amanda P., Hodge, Emily, Nelson, Carl P., Stewart, Ceri E., Swan, Caroline, Wain, Louise V., Artigas, María Soler, Melén, Erik, Ushey, Kevin, Hao, Ke, Lamontagne, Maxime, Bossé, Yohan, Postma, Dirkje S., Tobin, Martin D., Sayers, Ian, Hall, Ian P.
Publicado 2013

Macrophages with reduced expressions of classical M1 and M2 surface markers in human bronchoalveolar lavage fluid exhibit pro-inflammatory gene signatures

por Takiguchi, Hiroto, Yang, Chen X., Yang, Cheng Wei Tony, Sahin, Basak, Whalen, Beth A., Milne, Stephen, Akata, Kentaro, Yamasaki, Kei, Yang, Julia Shun Wei, Cheung, Chung Yan, Vander Werff, Ryan, McNagny, Kelly M., Leitao Filho, Fernando Sergio, Shaipanich, Tawimas, van Eeden, Stephan F., Obeidat, Ma’en, Leung, Janice M., Sin, Don D.
Publicado 2021

Prioritization of candidate causal genes for asthma in susceptibility loci derived from UK Biobank

por Valette, Kim, Li, Zhonglin, Bon-Baret, Valentin, Chignon, Arnaud, Bérubé, Jean-Christophe, Eslami, Aida, Lamothe, Jennifer, Gaudreault, Nathalie, Joubert, Philippe, Obeidat, Ma’en, van den Berge, Maarten, Timens, Wim, Sin, Don D., Nickle, David C., Hao, Ke, Labbé, Catherine, Godbout, Krystelle, Côté, Andréanne, Laviolette, Michel, Boulet, Louis-Philippe, Mathieu, Patrick, Thériault, Sébastien, Bossé, Yohan
Publicado 2021

The Ser82 RAGE Variant Affects Lung Function and Serum RAGE in Smokers and sRAGE Production In Vitro

por Miller, Suzanne, Henry, Amanda P., Hodge, Emily, Kheirallah, Alexander K., Billington, Charlotte K., Rimington, Tracy L., Bhaker, Sangita K., Obeidat, Ma’en, Melén, Erik, Merid, Simon K., Swan, Caroline, Gowland, Catherine, Nelson, Carl P., Stewart, Ceri E., Bolton, Charlotte E., Kilty, Iain, Malarstig, Anders, Parker, Stuart G., Moffatt, Miriam F., Wardlaw, Andrew J., Hall, Ian P., Sayers, Ian
Publicado 2016

The relationship between the epigenetic aging biomarker “grimage” and lung function in both the airway and blood of people living with HIV: An observational cohort study

por Hernández Cordero, Ana I, Yang, Chen Xi, Yang, Julia, Li, Xuan, Horvath, Steve, Shaipanich, Tawimas, MacIsaac, Julia, Lin, David, McEwen, Lisa, Kobor, Michael S., Guillemi, Silvia, Harris, Marianne, Lam, Wan, Lam, Stephen, Obeidat, Ma'en, Novak, Richard M., Hudson, Fleur, Klinker, Hartwig, Dharan, Nila, Montaner, Julio, Man, S.F. Paul, Kunisaki, Ken, Sin, Don D., Leung, Janice M.
Publicado 2022

Whole Exome Re-Sequencing Implicates CCDC38 and Cilia Structure and Function in Resistance to Smoking Related Airflow Obstruction

por Wain, Louise V., Sayers, Ian, Soler Artigas, María, Portelli, Michael A., Zeggini, Eleftheria, Obeidat, Ma'en, Sin, Don D., Bossé, Yohan, Nickle, David, Brandsma, Corry-Anke, Malarstig, Anders, Vangjeli, Ciara, Jelinsky, Scott A., John, Sally, Kilty, Iain, McKeever, Tricia, Shrine, Nick R. G., Cook, James P., Patel, Shrina, Spector, Tim D., Hollox, Edward J., Hall, Ian P., Tobin, Martin D.
Publicado 2014