Oligodendrocyte-derived IL-33 functions as a microglial survival factor during neuroinvasive flavivirus infection

por Norris, Geoffrey T., Ames, Joshua M., Ziegler, Steven F., Oberst, Andrew
Publicado 2023

Oligodendrocyte-derived IL-33 functions as a microglial survival factor during neuroinvasive flavivirus infection

por Norris, Geoffrey T., Ames, Joshua M., Ziegler, Steven F., Oberst, Andrew
Publicado 2023

Ubiquitin-dependent Degradation of p73 Is Inhibited by PML

por Bernassola, Francesca, Salomoni, Paolo, Oberst, Andrew, Di Como, Charles J., Pagano, Michele, Melino, Gerry, Pandolfi, Pier Paolo
Publicado 2004

CASPASE 8 inhibits programmed necrosis by processing CYLD

por O’Donnell, Marie Anne, Perez-Jimenez, Eva, Oberst, Andrew, Ng, Aylwin, Massoumi, Ramin, Xavier, Ramnik, Green, Douglas R., Ting, Adrian T.
Publicado 2011

Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis

por Oberst, Andrew, Dillon, Christopher P., Weinlich, Ricardo, McCormick, Laura L., Fitzgerald, Patrick, Pop, Cristina, Hakem, Razq, Salvesen, Guy S., Green, Douglas R.
Publicado 2011

Ubiquitination and proteasomal degradation of ATG12 regulates its proapoptotic activity

por Haller, Martina, Hock, Andreas K, Giampazolias, Evangelos, Oberst, Andrew, Green, Douglas R, Debnath, Jayanta, Ryan, Kevin M, Vousden, Karen H, Tait, Stephen W G
Publicado 2015

RIPK1 and RIPK3 regulate TNFα-induced β-cell death in concert with caspase activity

por Contreras, Christopher J., Mukherjee, Noyonika, Branco, Renato C.S., Lin, Li, Hogan, Meghan F., Cai, Erica P., Oberst, Andrew A., Kahn, Steven E., Templin, Andrew T.
Publicado 2022

Mito-priming as a method to engineer Bcl-2 addiction

por Lopez, Jonathan, Bessou, Margaux, Riley, Joel S., Giampazolias, Evangelos, Todt, Franziska, Rochegüe, Tony, Oberst, Andrew, Green, Douglas R., Edlich, Frank, Ichim, Gabriel, Tait, Stephen W. G.
Publicado 2016

CELLULAR RNA INTERACTS WITH MAVS TO PROMOTE ANTIVIRAL SIGNALING

por Gokhale, Nandan S., Somfleth, Kim, Thompson, Matthew G., Sam, Russell K., Marciniak, Daphnée M., Chu, Lan H., Park, Moonhee, Dvorkin, Steve, Oberst, Andrew, Horner, Stacy M., Ong, Shao-En, Gale, Michael, Savan, Ram
Publicado 2023

NPM1 directs PIDDosome-dependent caspase-2 activation in the nucleolus

por Ando, Kiyohiro, Parsons, Melissa J., Shah, Richa B., Charendoff, Chloé I., Paris, Sheré L., Liu, Peter H., Fassio, Sara R., Rohrman, Brittany A., Thompson, Ruth, Oberst, Andrew, Sidi, Samuel, Bouchier-Hayes, Lisa
Publicado 2017

T cells instruct myeloid cells to produce inflammasome-independent IL-1β and cause autoimmunity

por Jain, Aakanksha, Irizarry-Caro, Ricardo A., McDaniel, Margaret M., Chawla, Amanpreet Singh, Carroll, Kaitlin R., Overcast, Garrett R., Philip, Naomi H., Oberst, Andrew, Chervonsky, Alexander V., Katz, Jonathan D., Pasare, Chandrashekhar
Publicado 2019

Caspase-8 scaffolding function and MLKL regulate NLRP3 inflammasome activation downstream of TLR3

por Kang, Seokwon, Fernandes-Alnemri, Teresa, Rogers, Corey, Mayes, Lindsey, Wang, Ying, Dillon, Christopher, Roback, Linda, Kaiser, William, Oberst, Andrew, Sagara, Junji, Fitzgerald, Katherine A., Green, Douglas R., Zhang, Jianke, Mocarski, Edward S., Alnemri, Emad S.
Publicado 2015

Mitochondrial inner membrane permeabilisation enables mtDNA release during apoptosis

por Riley, Joel S, Quarato, Giovanni, Cloix, Catherine, Lopez, Jonathan, O'Prey, Jim, Pearson, Matthew, Chapman, James, Sesaki, Hiromi, Carlin, Leo M, Passos, João F, Wheeler, Ann P, Oberst, Andrew, Ryan, Kevin M, Tait, Stephen WG
Publicado 2018

STING is required for host defense against neuropathological West Nile virus infection

por McGuckin Wuertz, Kathryn, Treuting, Piper M., Hemann, Emily A., Esser-Nobis, Katharina, Snyder, Annelise G., Graham, Jessica B., Daniels, Brian P., Wilkins, Courtney, Snyder, Jessica M., Voss, Kathleen M., Oberst, Andrew, Lund, Jennifer, Gale, Michael
Publicado 2019

De novo necroptosis creates an inflammatory environment mediating tumor susceptibility to immune checkpoint inhibitors

por Workenhe, Samuel T., Nguyen, Andrew, Bakhshinyan, David, Wei, Jiarun, Hare, David N., MacNeill, Kelly L., Wan, Yonghong, Oberst, Andrew, Bramson, Jonathan L., Nasir, Jalees A., Vito, Alyssa, El-Sayes, Nader, Singh, Sheila K., McArthur, Andrew G., Mossman, Karen L.
Publicado 2020

Human ZBP1 induces cell death‐independent inflammatory signaling via RIPK3 and RIPK1

por Peng, Ruoshi, Wang, Chris Kedong, Wang‐Kan, Xuan, Idorn, Manja, Kjær, Majken, Zhou, Felix Y, Fiil, Berthe Katrine, Timmermann, Frederik, Orozco, Susana L, McCarthy, Julia, Leung, Carol S, Lu, Xin, Bagola, Katrin, Rehwinkel, Jan, Oberst, Andrew, Maelfait, Jonathan, Paludan, Søren R, Gyrd‐Hansen, Mads
Publicado 2022

Activity of Uncleaved Caspase-8 Controls Anti-bacterial Immune Defense and TLR-Induced Cytokine Production Independent of Cell Death

por Philip, Naomi H., DeLaney, Alexandra, Peterson, Lance W., Santos-Marrero, Melanie, Grier, Jennifer T., Sun, Yan, Wynosky-Dolfi, Meghan A., Zwack, Erin E., Hu, Baofeng, Olsen, Tayla M., Rongvaux, Anthony, Pope, Scott D., López, Carolina B., Oberst, Andrew, Beiting, Daniel P., Henao-Mejia, Jorge, Brodsky, Igor E.
Publicado 2016

Limited Mitochondrial Permeabilization Causes DNA Damage and Genomic Instability in the Absence of Cell Death

por Ichim, Gabriel, Lopez, Jonathan, Ahmed, Shafiq U., Muthalagu, Nathiya, Giampazolias, Evangelos, Delgado, M. Eugenia, Haller, Martina, Riley, Joel S., Mason, Susan M., Athineos, Dimitris, Parsons, Melissa J., van de Kooij, Bert, Bouchier-Hayes, Lisa, Chalmers, Anthony J., Rooswinkel, Rogier W., Oberst, Andrew, Blyth, Karen, Rehm, Markus, Murphy, Daniel J., Tait, Stephen W.G.
Publicado 2015

Limited Mitochondrial Permeabilization Causes DNA Damage and Genomic Instability in the Absence of Cell Death

por Ichim, Gabriel, Lopez, Jonathan, Ahmed, Shafiq U., Muthalagu, Nathiya, Giampazolias, Evangelos, Delgado, M. Eugenia, Haller, Martina, Riley, Joel S., Mason, Susan M., Athineos, Dimitris, Parsons, Melissa J., van de Kooij, Bert, Bouchier-Hayes, Lisa, Chalmers, Anthony J., Rooswinkel, Rogier W., Oberst, Andrew, Blyth, Karen, Rehm, Markus, Murphy, Daniel J., Tait, Stephen W.G.
Publicado 2015

Mitochondrial permeabilisation engages NF-κB dependent anti-tumour activity under caspase deficiency

por Giampazolias, Evangelos, Zunino, Barbara, Dhayade, Sandeep, Bock, Florian, Cloix, Catherine, Cao, Kai, Roca, Alba, Lopez, Jonathan, Ichim, Gabriel, Proïcs, Emma, Rubio-Patiño, Camila, Fort, Loic, Yatim, Nader, Woodham, Emma, Orozco, Susana, Taraborrelli, Lucia, Peltzer, Nieves, Lecis, Daniele, Machesky, Laura, Walczak, Henning, Albert, Matthew L., Milling, Simon, Oberst, Andrew, Ricci, Jean-Ehrland, Ryan, Kevin M., Blyth, Karen, Tait, Stephen W.G.
Publicado 2017