Development of 4H-pyridopyrimidines: a class of selective bacterial protein synthesis inhibitors

por Guiles, Joseph W, Toro, Andras, Ochsner, Urs A, Bullard, James M
Publicado 2012

Nucleic Acid Ligands With Protein-like Side Chains: Modified Aptamers and Their Use as Diagnostic and Therapeutic Agents

por Rohloff, John C, Gelinas, Amy D, Jarvis, Thale C, Ochsner, Urs A, Schneider, Daniel J, Gold, Larry, Janjic, Nebojsa
Publicado 2014

Elucidating Novel Serum Biomarkers Associated with Pulmonary Tuberculosis Treatment

por De Groote, Mary A., Nahid, Payam, Jarlsberg, Leah, Johnson, John L., Weiner, Marc, Muzanyi, Grace, Janjic, Nebojsa, Sterling, David G., Ochsner, Urs A.
Publicado 2013

Highly Multiplexed Proteomic Analysis of Quantiferon Supernatants To Identify Biomarkers of Latent Tuberculosis Infection

por De Groote, Mary Ann, Higgins, Michael, Hraha, Thomas, Wall, Kirsten, Wilson, Michael L., Sterling, David G., Janjic, Nebojsa, Reves, Randall, Ochsner, Urs A., Belknap, Robert
Publicado 2017

Discovery and Validation of a Six-Marker Serum Protein Signature for the Diagnosis of Active Pulmonary Tuberculosis

por De Groote, Mary A., Sterling, David G., Hraha, Thomas, Russell, Theresa M., Green, Louis S., Wall, Kirsten, Kraemer, Stephan, Ostroff, Rachel, Janjic, Nebojsa, Ochsner, Urs A.
Publicado 2017

Potential of High-Affinity, Slow Off-Rate Modified Aptamer Reagents for Mycobacterium tuberculosis Proteins as Tools for Infection Models and Diagnostic Applications

por Russell, Theresa M., Green, Louis S., Rice, Taylor, Kruh-Garcia, Nicole A., Dobos, Karen, De Groote, Mary A., Hraha, Thomas, Sterling, David G., Janjic, Nebojsa, Ochsner, Urs A.
Publicado 2017

Potency of the novel PolC DNA polymerase inhibitor CRS0540 in a disseminated Listeria monocytogenes intracellular hollow-fibre model

por Patel, Swati, Chapagain, Moti, Mason, Clifford, Gingrich, Matthew, Athale, Shruti, Ribble, Wendy, Hoang, Teresa, Day, Joshua, Sun, Xicheng, Jarvis, Thale, Ochsner, Urs A, Howe, David, Gumbo, Tawanda
Publicado 2022

Optimization and Lead Selection of Benzothiazole Amide Analogs Toward a Novel Antimycobacterial Agent

por De Groote, Mary A., Jarvis, Thale C., Wong, Christina, Graham, James, Hoang, Teresa, Young, Casey L., Ribble, Wendy, Day, Joshua, Li, Wei, Jackson, Mary, Gonzalez-Juarrero, Mercedes, Sun, Xicheng, Ochsner, Urs A.
Publicado 2018

Multiple-Ascending-Dose Phase 1 Clinical Study of the Safety, Tolerability, and Pharmacokinetics of CRS3123, a Narrow-Spectrum Agent with Minimal Disruption of Normal Gut Microbiot...

por Lomeli, Barbara K., Galbraith, Hal, Schettler, Jared, Saviolakis, George A., El-Amin, Wael, Osborn, Blaire, Ravel, Jacques, Hazleton, Keith, Lozupone, Catherine A., Evans, Ronald J., Bell, Stacie J., Ochsner, Urs A., Jarvis, Thale C., Baqar, Shahida, Janjic, Nebojsa
Publicado 2019

Sequential inflammatory processes define human progression from M. tuberculosis infection to tuberculosis disease

por Scriba, Thomas J., Penn-Nicholson, Adam, Shankar, Smitha, Hraha, Tom, Thompson, Ethan G., Sterling, David, Nemes, Elisa, Darboe, Fatoumatta, Suliman, Sara, Amon, Lynn M., Mahomed, Hassan, Erasmus, Mzwandile, Whatney, Wendy, Johnson, John L., Boom, W. Henry, Hatherill, Mark, Valvo, Joe, De Groote, Mary Ann, Ochsner, Urs A., Aderem, Alan, Hanekom, Willem A., Zak, Daniel E.
Publicado 2017