Editorial: Risk Factors and Outcome Predicating Biomarker of Neurodegenerative Diseases

por Hu, Chaur-Jong, Octave, Jean-Noël
Publicado 2019

Alzheimer’s Disease, a Lipid Story: Involvement of Peroxisome Proliferator-Activated Receptor α

por Sáez-Orellana, Francisco, Octave, Jean-Noël, Pierrot, Nathalie
Publicado 2020

Epigenetic Regulations of Immediate Early Genes Expression Involved in Memory Formation by the Amyloid Precursor Protein of Alzheimer Disease

por Hendrickx, Aurélie, Pierrot, Nathalie, Tasiaux, Bernadette, Schakman, Olivier, Kienlen-Campard, Pascal, De Smet, Charles, Octave, Jean-Noël
Publicado 2014

Glycines from the APP GXXXG/GXXXA Transmembrane Motifs Promote Formation of Pathogenic Aβ Oligomers in Cells

por Decock, Marie, Stanga, Serena, Octave, Jean-Noël, Dewachter, Ilse, Smith, Steven O., Constantinescu, Stefan N., Kienlen-Campard, Pascal
Publicado 2016

Activation of phagocytic activity in astrocytes by reduced expression of the inflammasome component ASC and its implication in a mouse model of Alzheimer disease

por Couturier, Julien, Stancu, Ilie-Cosmin, Schakman, Olivier, Pierrot, Nathalie, Huaux, François, Kienlen-Campard, Pascal, Dewachter, Ilse, Octave, Jean-Noël
Publicado 2016

Epigenetic Induction of EGR-1 Expression by the Amyloid Precursor Protein during Exposure to Novelty

por Hendrickx, Aurélie, Pierrot, Nathalie, Tasiaux, Bernadette, Schakman, Olivier, Brion, Jean-Pierre, Kienlen-Campard, Pascal, De Smet, Charles, Octave, Jean-Noël
Publicado 2013

Analysis by a highly sensitive split luciferase assay of the regions involved in APP dimerization and its impact on processing

por Decock, Marie, El Haylani, Laetitia, Stanga, Serena, Dewachter, Ilse, Octave, Jean-Noël, Smith, Steven O., Constantinescu, Stefan N., Kienlen-Campard, Pascal
Publicado 2015

A Role for GDNF and Soluble APP as Biomarkers of Amyotrophic Lateral Sclerosis Pathophysiology

por Stanga, Serena, Brambilla, Liliana, Tasiaux, Bernadette, Dang, Anh H., Ivanoiu, Adrian, Octave, Jean-Noël, Rossi, Daniela, van Pesch, Vincent, Kienlen-Campard, Pascal
Publicado 2018

Contribution of the Endosomal-Lysosomal and Proteasomal Systems in Amyloid-β Precursor Protein Derived Fragments Processing

por Evrard, Caroline, Kienlen-Campard, Pascal, Coevoet, Mathilde, Opsomer, Rémi, Tasiaux, Bernadette, Melnyk, Patricia, Octave, Jean-Noël, Buée, Luc, Sergeant, Nicolas, Vingtdeux, Valérie
Publicado 2018

Conditional deletion of KCC2 impairs synaptic plasticity and both spatial and nonspatial memory

por Kreis, Anna, Issa, Farah, Yerna, Xavier, Jabbour, Caren, Schakman, Olivier, de Clippele, Marie, Tajeddine, Nicolas, Pierrot, Nathalie, Octave, Jean-Noël, Gualdani, Roberta, Gailly, Philippe
Publicado 2023

β-Sheet Structure within the Extracellular Domain of C99 Regulates Amyloidogenic Processing

por Hu, Yi, Kienlen-Campard, Pascal, Tang, Tzu-Chun, Perrin, Florian, Opsomer, Rémi, Decock, Marie, Pan, Xiaoshu, Octave, Jean-Noel, Constantinescu, Stefan N., Smith, Steven O.
Publicado 2017

Aggregated Tau activates NLRP3–ASC inflammasome exacerbating exogenously seeded and non-exogenously seeded Tau pathology in vivo

por Stancu, Ilie-Cosmin, Cremers, Niels, Vanrusselt, Hannah, Couturier, Julien, Vanoosthuyse, Alexandre, Kessels, Sofie, Lodder, Chritica, Brône, Bert, Huaux, François, Octave, Jean-Noël, Terwel, Dick, Dewachter, Ilse
Publicado 2019

Presenilin 2-Dependent Maintenance of Mitochondrial Oxidative Capacity and Morphology

por Contino, Sabrina, Porporato, Paolo E., Bird, Matthew, Marinangeli, Claudia, Opsomer, Rémi, Sonveaux, Pierre, Bontemps, Françoise, Dewachter, Ilse, Octave, Jean-Noël, Bertrand, Luc, Stanga, Serena, Kienlen-Campard, Pascal
Publicado 2017

Heterotypic seeding of Tau fibrillization by pre-aggregated Abeta provides potent seeds for prion-like seeding and propagation of Tau-pathology in vivo

por Vasconcelos, Bruno, Stancu, Ilie-Cosmin, Buist, Arjan, Bird, Matthew, Wang, Peng, Vanoosthuyse, Alexandre, Van Kolen, Kristof, Verheyen, An, Kienlen-Campard, Pascal, Octave, Jean-Noël, Baatsen, Peter, Moechars, Diederik, Dewachter, Ilse
Publicado 2016

Cortical cells reveal APP as a new player in the regulation of GABAergic neurotransmission

por Doshina, Anna, Gourgue, Florian, Onizuka, Michiho, Opsomer, Remi, Wang, Peng, Ando, Kunie, Tasiaux, Bernadette, Dewachter, Ilse, Kienlen-Campard, Pascal, Brion, Jean-Pierre, Gailly, Philippe, Octave, Jean-Noël, Pierrot, Nathalie
Publicado 2017

Regulation of PPARα by APP in Alzheimer disease affects the pharmacological modulation of synaptic activity

por Sáez-Orellana, Francisco, Leroy, Thomas, Ribeiro, Floriane, Kreis, Anna, Leroy, Karelle, Lalloyer, Fanny, Baugé, Eric, Staels, Bart, Duyckaerts, Charles, Brion, Jean-Pierre, Gailly, Philippe, Octave, Jean-Noël, Pierrot, Nathalie
Publicado 2021

Amyloid Precursor Protein (APP) Controls the Expression of the Transcriptional Activator Neuronal PAS Domain Protein 4 (NPAS4) and Synaptic GABA Release

por Opsomer, Rémi, Contino, Sabrina, Perrin, Florian, Gualdani, Roberta, Tasiaux, Bernadette, Doyen, Pierre, Vergouts, Maxime, Vrancx, Céline, Doshina, Anna, Pierrot, Nathalie, Octave, Jean-Noël, Gailly, Philippe, Stanga, Serena, Kienlen-Campard, Pascal
Publicado 2020

Overexpression of wild-type human amyloid precursor protein alters GABAergic transmission

por Kreis, Anna, Desloovere, Jana, Suelves, Nuria, Pierrot, Nathalie, Yerna, Xavier, Issa, Farah, Schakman, Olivier, Gualdani, Roberta, de Clippele, Marie, Tajeddine, Nicolas, Kienlen-Campard, Pascal, Raedt, Robrecht, Octave, Jean-Noël, Gailly, Philippe
Publicado 2021

Tau interactome mapping based identification of Otub1 as Tau deubiquitinase involved in accumulation of pathological Tau forms in vitro and in vivo

por Wang, Peng, Joberty, Gerard, Buist, Arjan, Vanoosthuyse, Alexandre, Stancu, Ilie-Cosmin, Vasconcelos, Bruno, Pierrot, Nathalie, Faelth-Savitski, Maria, Kienlen-Campard, Pascal, Octave, Jean-Noël, Bantscheff, Marcus, Drewes, Gerard, Moechars, Diederik, Dewachter, Ilse
Publicado 2017

Increasing membrane cholesterol of neurons in culture recapitulates Alzheimer’s disease early phenotypes

por Marquer, Catherine, Laine, Jeanne, Dauphinot, Luce, Hanbouch, Linda, Lemercier-Neuillet, Camille, Pierrot, Nathalie, Bossers, Koen, Le, Mickael, Corlier, Fabian, Benstaali, Caroline, Saudou, Frédéric, Thinakaran, Gopal, Cartier, Nathalie, Octave, Jean-Noël, Duyckaerts, Charles, Potier, Marie-Claude
Publicado 2014