Fragment Binding to Kinase Hinge: If Charge Distribution and Local pK (a) Shifts Mislead Popular Bioisosterism Concepts

por Oebbeke, Matthias, Siefker, Christof, Wagner, Björn, Heine, Andreas, Klebe, Gerhard
Publicado 2020

Two Methods, One Goal: Structural Differences between Cocrystallization and Crystal Soaking to Discover Ligand Binding Poses

por Wienen‐Schmidt, Barbara, Oebbeke, Matthias, Ngo, Khang, Heine, Andreas, Klebe, Gerhard
Publicado 2020

Phospholamban pentamerization increases sensitivity and dynamic range of cardiac relaxation

por Funk, Florian, Kronenbitter, Annette, Hackert, Katarzyna, Oebbeke, Matthias, Klebe, Gerhard, Barth, Mareike, Koch, Daniel, Schmitt, Joachim P
Publicado 2023