In vitro and in vivo characterization of three Cellvibrio japonicus glycoside hydrolase family 5 members reveals potent xyloglucan backbone-cleaving functions

por Attia, Mohamed A., Nelson, Cassandra E., Offen, Wendy A., Jain, Namrata, Davies, Gideon J., Gardner, Jeffrey G., Brumer, Harry
Publicado 2018

Structural and functional insight into human O-GlcNAcase

por Roth, Christian, Chan, Sherry, Offen, Wendy A, Hemsworth, Glyn R, Willems, Lianne I, King, Dustin T, Varghese, Vimal, Britton, Robert, Vocadlo, David J, Davies, Gideon J
Publicado 2017

Structure and Activity of Paenibacillus polymyxa Xyloglucanase from Glycoside Hydrolase Family 44

por Ariza, Antonio, Eklöf, Jens M., Spadiut, Oliver, Offen, Wendy A., Roberts, Shirley M., Besenmatter, Werner, Friis, Esben P., Skjøt, Michael, Wilson, Keith S., Brumer, Harry, Davies, Gideon
Publicado 2011

Three-dimensional structures of two heavily N-glycosylated Aspergillus sp. family GH3 β-d-glucosidases

por Agirre, Jon, Ariza, Antonio, Offen, Wendy A., Turkenburg, Johan P., Roberts, Shirley M., McNicholas, Stuart, Harris, Paul V., McBrayer, Brett, Dohnalek, Jan, Cowtan, Kevin D., Davies, Gideon J., Wilson, Keith S.
Publicado 2016

Development of Non‐Hydrolysable Oligosaccharide Activity‐Based Inactivators for Endoglycanases: A Case Study on α‐1,6 Mannanases

por Schröder, Sybrin P., Offen, Wendy A., Males, Alexandra, Jin, Yi, de Boer, Casper, Enotarpi, Jacopo, Marino, Laura, van der Marel, Gijsbert A., Florea, Bogdan I., Codée, Jeroen D. C., Overkleeft, Herman S., Davies, Gideon J.
Publicado 2021

Synthesis of broad-specificity activity-based probes for exo-β-mannosidases

por McGregor, Nicholas G. S., Kuo, Chi-Lin, Beenakker, Thomas J. M., Wong, Chun-Sing, Offen, Wendy A., Armstrong, Zachary, Florea, Bogdan I., Codée, Jeroen D. C., Overkleeft, Herman S., Aerts, Johannes M. F. G., Davies, Gideon J.
Publicado 2021

Design, Synthesis and Structural Analysis of Glucocerebrosidase Imaging Agents

por Rowland, Rhianna J., Chen, Yurong, Breen, Imogen, Wu, Liang, Offen, Wendy A., Beenakker, Thomas J., Su, Qin, van den Nieuwendijk, Adrianus M. C. H., Aerts, Johannes M. F. G., Artola, Marta, Overkleeft, Herman S., Davies, Gideon J.
Publicado 2021

Gluco-1H-imidazole: A New Class of Azole-Type β-Glucosidase Inhibitor

por Schröder, Sybrin P., Wu, Liang, Artola, Marta, Hansen, Thomas, Offen, Wendy A., Ferraz, Maria J., Li, Kah-Yee, Aerts, Johannes M. F. G., van der Marel, Gijsbert A., Codée, Jeroen D. C., Davies, Gideon J., Overkleeft, Herman S.
Publicado 2018

1,6-Cyclophellitol Cyclosulfates: A New Class of Irreversible Glycosidase Inhibitor

por Artola, Marta, Wu, Liang, Ferraz, Maria J., Kuo, Chi-Lin, Raich, Lluís, Breen, Imogen Z., Offen, Wendy A., Codée, Jeroen D. C., van der Marel, Gijsbert A., Rovira, Carme, Aerts, Johannes M. F. G., Davies, Gideon J., Overkleeft, Herman S.
Publicado 2017

Mechanistic Insights into the Chaperoning of Human Lysosomal-Galactosidase Activity: Highly Functionalized Aminocyclopentanes and C-5a-Substituted Derivatives of 4-epi-Isofagomine

por Weber, Patrick, Thonhofer, Martin, Averill, Summer, Davies, Gideon J., Santana, Andres Gonzalez, Müller, Philipp, Nasseri, Seyed A., Offen, Wendy A., Pabst, Bettina M., Paschke, Eduard, Schalli, Michael, Torvisco, Ana, Tschernutter, Marion, Tysoe, Christina, Windischhofer, Werner, Withers, Stephen G., Wolfsgruber, Andreas, Wrodnigg, Tanja M., Stütz, Arnold E.
Publicado 2020

Carba-cyclophellitols Are Neutral Retaining-Glucosidase Inhibitors

por Beenakker, Thomas J. M., Wander, Dennis P. A., Offen, Wendy A., Artola, Marta, Raich, Lluís, Ferraz, Maria J., Li, Kah-Yee, Houben, Judith H. P. M., van Rijssel, Erwin R., Hansen, Thomas, van der Marel, Gijsbert A., Codée, Jeroen D. C., Aerts, Johannes M. F. G., Rovira, Carme, Davies, Gideon J., Overkleeft, Herman S.
Publicado 2017