Targeting immune-checkpoint inhibitor resistance mechanisms by MEK inhibitor and agonist anti-CD40 antibody combination therapy

por Baumann, Daniel, Offringa, Rienk
Publicado 2020

CD4 T Cells and Their Role in Antitumor Immune Responses

por Toes, René E.M., Ossendorp, Ferry, Offringa, Rienk, Melief, Cornelis J.M.
Publicado 1999

Phenotype, function and T cell receptor repertoire of tumor-infiltrating lymphocytes in patients with pancreatic ductal adenocarcinoma

por Poschke, Isabel, Flossdorf, Michael, Faryna, Marta, Bergmann, Frank, Hassel, Jessica, Strobel, Oliver, Offringa, Rienk
Publicado 2015

Immune Escape of Tumors in Vivo by Expression of Cellular Flice-Inhibitory Protein

por Medema, Jan Paul, de Jong, Joan, van Hall, Thorbald, Melief, Cornelis J.M., Offringa, Rienk
Publicado 1999

Differential Influence on Cytotoxic T Lymphocyte Epitope Presentation by Controlled Expression of Either Proteasome Immunosubunits or Pa28

por van Hall, Thorbald, Sijts, Alice, Camps, Marcel, Offringa, Rienk, Melief, Cornelis, Kloetzel, Peter-M., Ossendorp, Ferry
Publicado 2000

The m(6)A-Related mRNA Signature Predicts the Prognosis of Pancreatic Cancer Patients

por Meng, Zibo, Yuan, Qingchen, Zhao, Jingyuan, Wang, Bo, Li, Shoukang, Offringa, Rienk, Jin, Xin, Wu, Heshui
Publicado 2020

p38 MAPK signaling in M1 macrophages results in selective elimination of M2 macrophages by MEK inhibition

por Baumann, Daniel, Drebant, Jennifer, Hägele, Tanja, Burger, Luisa, Serger, Clara, Lauenstein, Claudia, Dudys, Przemyslaw, Erdmann, Gerrit, Offringa, Rienk
Publicado 2021

Radiation-induced alterations in immunogenicity of a murine pancreatic ductal adenocarcinoma cell line

por Schröter, Philipp, Hartmann, Laura, Osen, Wolfram, Baumann, Daniel, Offringa, Rienk, Eisel, David, Debus, Jürgen, Eichmüller, Stefan B., Rieken, Stefan
Publicado 2020

Photon versus carbon ion irradiation: immunomodulatory effects exerted on murine tumor cell lines

por Hartmann, Laura, Schröter, Philipp, Osen, Wolfram, Baumann, Daniel, Offringa, Rienk, Moustafa, Mahmoud, Will, Rainer, Debus, Jürgen, Brons, Stephan, Rieken, Stefan, Eichmüller, Stefan B.
Publicado 2020

Novel Non-integrating DNA Nano-S/MAR Vectors Restore Gene Function in Isogenic Patient-Derived Pancreatic Tumor Models

por Bozza, Matthias, Green, Edward W., Espinet, Elisa, De Roia, Alice, Klein, Corinna, Vogel, Vanessa, Offringa, Rienk, Williams, James A., Sprick, Martin, Harbottle, Richard P.
Publicado 2020

Human Papillomavirus Deregulates the Response of a Cellular Network Comprising of Chemotactic and Proinflammatory Genes

por Karim, Rezaul, Meyers, Craig, Backendorf, Claude, Ludigs, Kristina, Offringa, Rienk, van Ommen, Gert-Jan B., Melief, Cornelis J. M., van der Burg, Sjoerd H., Boer, Judith M.
Publicado 2011

The nonpolymorphic MHC Qa-1(b) mediates CD8(+) T cell surveillance of antigen-processing defects

por Oliveira, Cláudia C., van Veelen, Peter A., Querido, Bianca, de Ru, Arnoud, Sluijter, Marjolein, Laban, Sandra, Drijfhout, Jan W., van der Burg, Sjoerd H., Offringa, Rienk, van Hall, Thorbald
Publicado 2010

The nonpolymorphic MHC Qa-1(b) mediates CD8(+) T cell surveillance of antigen-processing defects

por Oliveira, Cláudia C., van Veelen, Peter A., Querido, Bianca, de Ru, Arnoud, Sluijter, Marjolein, Laban, Sandra, Drijfhout, Jan W., van der Burg, Sjoerd H., Offringa, Rienk, van Hall, Thorbald
Publicado 2010

Secretogranin II influences the assembly and function of MHC class I in melanoma

por Steinfass, Tamara, Poelchen, Juliane, Sun, Qian, Mastrogiulio, Giovanni, Novak, Daniel, Vierthaler, Marlene, Pardo, Sandra, Federico, Aniello, Hüser, Laura, Hielscher, Thomas, Carretero, Rafael, Offringa, Rienk, Altevogt, Peter, Umansky, Viktor, Utikal, Jochen
Publicado 2023

Sensitization of Tumors for Attack by Virus-Specific CD8+ T-Cells Through Antibody-Mediated Delivery of Immunogenic T-Cell Epitopes

por Sefrin, Julian P., Hillringhaus, Lars, Mundigl, Olaf, Mann, Karin, Ziegler-Landesberger, Doris, Seul, Heike, Tabares, Gloria, Knoblauch, Dominic, Leinenbach, Andreas, Friligou, Irene, Dziadek, Sebastian, Offringa, Rienk, Lifke, Valeria, Lifke, Alexander
Publicado 2019

Synergism of Cytotoxic T Lymphocyte–Associated Antigen 4 Blockade and Depletion of Cd25(+) Regulatory T Cells in Antitumor Therapy Reveals Alternative Pathways for Suppression of A...

por Sutmuller, Roger P.M., van Duivenvoorde, Leonie M., van Elsas, Andrea, Schumacher, Ton N.M., Wildenberg, Manon E., Allison, James P., Toes, Rene E.M., Offringa, Rienk, Melief, Cornelis J.M.
Publicado 2001

Elucidating the Autoimmune and Antitumor Effector Mechanisms of a Treatment Based on Cytotoxic T Lymphocyte Antigen-4 Blockade in Combination with a B16 Melanoma Vaccine: Compariso...

por van Elsas, Andrea, Sutmuller, Roger P.M., Hurwitz, Arthur A., Ziskin, Jennifer, Villasenor, Jennifer, Medema, Jan-Paul, Overwijk, Willem W., Restifo, Nicholas P., Melief, Cornelis J.M., Offringa, Rienk, Allison, James P.
Publicado 2001

A high-throughput RNAi screen for detection of immune-checkpoint molecules that mediate tumor resistance to cytotoxic T lymphocytes

por Khandelwal, Nisit, Breinig, Marco, Speck, Tobias, Michels, Tillmann, Kreutzer, Christiane, Sorrentino, Antonio, Sharma, Ashwini Kumar, Umansky, Ludmila, Conrad, Heinke, Poschke, Isabel, Offringa, Rienk, König, Rainer, Bernhard, Helga, Machlenkin, Arthur, Boutros, Michael, Beckhove, Philipp
Publicado 2015

Proimmunogenic impact of MEK inhibition synergizes with agonist anti-CD40 immunostimulatory antibodies in tumor therapy

por Baumann, Daniel, Hägele, Tanja, Mochayedi, Julian, Drebant, Jennifer, Vent, Caroline, Blobner, Sven, Noll, Julia Han, Nickel, Irena, Schumacher, Corinna, Boos, Sophie Luise, Daniel, Aline Sophie, Wendler, Susann, Volkmar, Michael, Strobel, Oliver, Offringa, Rienk
Publicado 2020

Immature Dendritic Cells Acquire Cd8(+)Cytotoxic T Lymphocyte Priming Capacity upon Activation by T Helper Cell–Independent or–Dependent Stimuli

por Schuurhuis, Danita H., Laban, Sandra, Toes, René E.M., Ricciardi-Castagnoli, Paola, Kleijmeer, Monique J., van der Voort, Ellen I.H., Rea, Delphine, Offringa, Rienk, Geuze, Hans J., Melief, Cornelis J.M., Ossendorp, Ferry
Publicado 2000