The Curious Case of the Nidovirus Exoribonuclease: Its Role in RNA Synthesis and Replication Fidelity

por Ogando, Natacha S., Ferron, Francois, Decroly, Etienne, Canard, Bruno, Posthuma, Clara C., Snijder, Eric J.
Publicado 2019

The Enzymatic Activity of the nsp14 Exoribonuclease Is Critical for Replication of MERS-CoV and SARS-CoV-2

por Ogando, Natacha S., Zevenhoven-Dobbe, Jessika C., van der Meer, Yvonne, Bredenbeek, Peter J., Posthuma, Clara C., Snijder, Eric J.
Publicado 2020

Host factor prioritization for pan-viral genetic perturbation screens using random intercept models and network propagation

por Dirmeier, Simon, Dächert, Christopher, van Hemert, Martijn, Tas, Ali, Ogando, Natacha S., van Kuppeveld, Frank, Bartenschlager, Ralf, Kaderali, Lars, Binder, Marco, Beerenwinkel, Niko
Publicado 2020

Suramin Inhibits SARS-CoV-2 Infection in Cell Culture by Interfering with Early Steps of the Replication Cycle

por Salgado-Benvindo, Clarisse, Thaler, Melissa, Tas, Ali, Ogando, Natacha S., Bredenbeek, Peter J., Ninaber, Dennis K., Wang, Ying, Hiemstra, Pieter S., Snijder, Eric J., van Hemert, Martijn J.
Publicado 2020

Genome-wide mapping of SARS-CoV-2 RNA structures identifies therapeutically-relevant elements

por Manfredonia, Ilaria, Nithin, Chandran, Ponce-Salvatierra, Almudena, Ghosh, Pritha, Wirecki, Tomasz K, Marinus, Tycho, Ogando, Natacha S, Snijder, Eric J, van Hemert, Martijn J, Bujnicki, Janusz M, Incarnato, Danny
Publicado 2020

Structure–function analysis of the nsp14 N7–guanine methyltransferase reveals an essential role in Betacoronavirus replication

por Ogando, Natacha S., El Kazzi, Priscila, Zevenhoven-Dobbe, Jessika C., Bontes, Brenda W., Decombe, Alice, Posthuma, Clara C., Thiel, Volker, Canard, Bruno, Ferron, François, Decroly, Etienne, Snijder, Eric J.
Publicado 2021

The Cyclophilin-Dependent Calcineurin Inhibitor Voclosporin Inhibits SARS-CoV-2 Replication in Cell Culture

por Ogando, Natacha S., Metscher, Erik, Moes, Dirk Jan A. R., Arends, Eline J., Tas, Ali, Cross, Jennifer, Snijder, Eric J., Teng, Y. K. Onno, de Vries, Aiko P. J., van Hemert, Martijn J.
Publicado 2022

Impact of Changes in Human Airway Epithelial Cellular Composition and Differentiation on SARS-CoV-2 Infection Biology

por Thaler, Melissa, Wang, Ying, van der Does, Anne M., Faiz, Alen, Ninaber, Dennis K., Ogando, Natacha S., Beckert, Hendrik, Taube, Christian, Salgado-Benvindo, Clarisse, Snijder, Eric J., Bredenbeek, Peter J., Hiemstra, Pieter S., van Hemert, Martijn J.
Publicado 2023

SARS-coronavirus-2 replication in Vero E6 cells: replication kinetics, rapid adaptation and cytopathology

por Ogando, Natacha S., Dalebout, Tim J., Zevenhoven-Dobbe, Jessika C., Limpens, Ronald W.A.L., van der Meer, Yvonne, Caly, Leon, Druce, Julian, de Vries, Jutte J. C., Kikkert, Marjolein, Bárcena, Montserrat, Sidorov, Igor, Snijder, Eric J.
Publicado 2020

Design, Synthesis, and Anti-RNA Virus Activity of 6′-Fluorinated-Aristeromycin Analogues

por Yoon, Ji-seong, Kim, Gyudong, Jarhad, Dnyandev B., Kim, Hong-Rae, Shin, Young-Sup, Qu, Shuhao, Sahu, Pramod K., Kim, Hea Ok, Lee, Hyuk Woo, Wang, Su Bin, Kong, Yun Jeong, Chang, Tong-Shin, Ogando, Natacha S., Kovacikova, Kristina, Snijder, Eric J., Posthuma, Clara C., van Hemert, Martijn J., Jeong, Lak Shin
Publicado 2019

Genomic monitoring of SARS-CoV-2 uncovers an Nsp1 deletion variant that modulates type I interferon response

por Lin, Jing-wen, Tang, Chao, Wei, Han-cheng, Du, Baowen, Chen, Chuan, Wang, Minjin, Zhou, Yongzhao, Yu, Ming-xia, Cheng, Lu, Kuivanen, Suvi, Ogando, Natacha S., Levanov, Lev, Zhao, Yuancun, Li, Chang-ling, Zhou, Ran, Li, Zhidan, Zhang, Yiming, Sun, Ke, Wang, Chengdi, Chen, Li, Xiao, Xia, Zheng, Xiuran, Chen, Sha-sha, Zhou, Zhen, Yang, Ruirui, Zhang, Dan, Xu, Mengying, Song, Junwei, Wang, Danrui, Li, Yupeng, Lei, ShiKun, Zeng, Wanqin, Yang, Qingxin, He, Ping, Zhang, Yaoyao, Zhou, Lifang, Cao, Ling, Luo, Feng, Liu, Huayi, Wang, Liping, Ye, Fei, Zhang, Ming, Li, Mengjiao, Fan, Wei, Li, Xinqiong, Li, Kaiju, Ke, Bowen, Xu, Jiannan, Yang, Huiping, He, Shusen, Pan, Ming, Yan, Yichen, Zha, Yi, Jiang, Lingyu, Yu, Changxiu, Liu, Yingfen, Xu, Zhiyong, Li, Qingfeng, Jiang, Yongmei, Sun, Jiufeng, Hong, Wei, Wei, Hongping, Lu, Guangwen, Vapalahti, Olli, Luo, Yunzi, Wei, Yuquan, Connor, Thomas, Tan, Wenjie, Snijder, Eric J., Smura, Teemu, Li, Weimin, Geng, Jia, Ying, Binwu, Chen, Lu
Publicado 2021