RNA editing enzyme ADAR1 governs the circadian expression of P-glycoprotein in human renal cells by regulating alternative splicing of the ABCB1 gene

por Omata, Yuji, Yamauchi, Tomoaki, Tsuruta, Akito, Matsunaga, Naoya, Koyanagi, Satoru, Ohdo, Shigehiro
Publicado 2021

Dysfunction of the circadian transcriptional factor CLOCK in mice resists chemical carcinogen-induced tumorigenesis

por Hashikawa, Ken-ichi, Katamune, Chiharu, Kusunose, Naoki, Matsunaga, Naoya, Koyanagi, Satoru, Ohdo, Shigehiro
Publicado 2017

RNA editing enzyme ADAR1 controls miR-381-3p-mediated expression of multidrug resistance protein MRP4 via regulation of circRNA in human renal cells

por Omata, Yuji, Okawa, Maseri, Haraguchi, Mai, Tsuruta, Akito, Matsunaga, Naoya, Koyanagi, Satoru, Ohdo, Shigehiro
Publicado 2022

Diurnal Expression of PD-1 on Tumor-Associated Macrophages Underlies the Dosing Time-Dependent Antitumor Effects of the PD-1/PD-L1 Inhibitor BMS-1 in B16/BL6 Melanoma-Bearing Mice

por Tsuruta, Akito, Shiiba, Yuki, Matsunaga, Naoya, Fujimoto, Marina, Yoshida, Yuya, Koyanagi, Satoru, Ohdo, Shigehiro
Publicado 2022

Ozagrel hydrochloride, a selective thromboxane A(2) synthase inhibitor, alleviates liver injury induced by acetaminophen overdose in mice

por Tomishima, Yoshiro, Ishitsuka, Yoichi, Matsunaga, Naoya, Nagatome, Minako, Furusho, Hirokazu, Irikura, Mitsuru, Ohdo, Shigehiro, Irie, Tetsumi
Publicado 2013

Molecular basis for the dosing time-dependency of anti-allodynic effects of gabapentin in a mouse model of neuropathic pain

por Kusunose, Naoki, Koyanagi, Satoru, Hamamura, Kengo, Matsunaga, Naoya, Yoshida, Miyako, Uchida, Takahiro, Tsuda, Makoto, Inoue, Kazuhide, Ohdo, Shigehiro
Publicado 2010

Diurnal expression of MRP4 in bone marrow cells underlies the dosing-time dependent changes in the oxaliplatin-induced myelotoxicity

por Kato, Mizuki, Tsurudome, Yuya, Kanemitsu, Takumi, Yasukochi, Sai, Kanado, Yuki, Ogino, Takashi, Matsunaga, Naoya, Koyanagi, Satoru, Ohdo, Shigehiro
Publicado 2020

Post-transcriptional repression of circadian component CLOCK regulates cancer-stemness in murine breast cancer cells

por Ogino, Takashi, Matsunaga, Naoya, Tanaka, Takahiro, Tanihara, Tomohito, Terajima, Hideki, Yoshitane, Hikari, Fukada, Yoshitaka, Tsuruta, Akito, Koyanagi, Satoru, Ohdo, Shigehiro
Publicado 2021

IL-6 Receptor Is a Possible Target against Growth of Metastasized Lung Tumor Cells in the Brain

por Noda, Mami, Yamakawa, Yukiko, Matsunaga, Naoya, Naoe, Satoko, Jodoi, Taishi, Yamafuji, Megumi, Akimoto, Nozomi, Teramoto, Norihiro, Fujita, Kyota, Ohdo, Shigehiro, Iguchi, Haruo
Publicado 2012

The intrinsic microglial molecular clock controls synaptic strength via the circadian expression of cathepsin S

por Hayashi, Yoshinori, Koyanagi, Satoru, Kusunose, Naoki, Okada, Ryo, Wu, Zhou, Tozaki-Saitoh, Hidetoshi, Ukai, Kiyoharu, Kohsaka, Shinichi, Inoue, Kazuhide, Ohdo, Shigehiro, Nakanishi, Hiroshi
Publicado 2013

Circadian clock component PERIOD2 regulates diurnal expression of Na(+)/H(+) exchanger regulatory factor-1 and its scaffolding function

por Tsurudome, Yuya, Koyanagi, Satoru, Kanemitsu, Takumi, Katamune, Chiharu, Oda, Masayuki, Kanado, Yuki, Kato, Mizuki, Morita, Akari, Tahara, Yu, Matsunaga, Naoya, Shibata, Shigenobu, Ohdo, Shigehiro
Publicado 2018

Omeprazole Suppresses Oxaliplatin-Induced Peripheral Neuropathy in a Rodent Model and Clinical Database

por Mine, Keisuke, Kawashiri, Takehiro, Inoue, Mizuki, Kobayashi, Daisuke, Mori, Kohei, Hiromoto, Shiori, Kudamatsu, Hibiki, Uchida, Mayako, Egashira, Nobuaki, Koyanagi, Satoru, Ohdo, Shigehiro, Shimazoe, Takao
Publicado 2022

Alteration of circadian machinery in monocytes underlies chronic kidney disease-associated cardiac inflammation and fibrosis

por Yoshida, Yuya, Matsunaga, Naoya, Nakao, Takaharu, Hamamura, Kengo, Kondo, Hideaki, Ide, Tomomi, Tsutsui, Hiroyuki, Tsuruta, Akito, Kurogi, Masayuki, Nakaya, Michio, Kurose, Hitoshi, Koyanagi, Satoru, Ohdo, Shigehiro
Publicado 2021

Glucocorticoid regulation of ATP release from spinal astrocytes underlies diurnal exacerbation of neuropathic mechanical allodynia

por Koyanagi, Satoru, Kusunose, Naoki, Taniguchi, Marie, Akamine, Takahiro, Kanado, Yuki, Ozono, Yui, Masuda, Takahiro, Kohro, Yuta, Matsunaga, Naoya, Tsuda, Makoto, Salter, Michael W., Inoue, Kazuhide, Ohdo, Shigehiro
Publicado 2016

Inhibition of G0/G1 Switch 2 Ameliorates Renal Inflammation in Chronic Kidney Disease

por Matsunaga, Naoya, Ikeda, Eriko, Kakimoto, Keisuke, Watanabe, Miyako, Shindo, Naoya, Tsuruta, Akito, Ikeyama, Hisako, Hamamura, Kengo, Higashi, Kazuhiro, Yamashita, Tomohiro, Kondo, Hideaki, Yoshida, Yuya, Matsuda, Masaki, Ogino, Takashi, Tokushige, Kazutaka, Itcho, Kazufumi, Furuichi, Yoko, Nakao, Takaharu, Yasuda, Kaori, Doi, Atsushi, Amamoto, Toshiaki, Aramaki, Hironori, Tsuda, Makoto, Inoue, Kazuhide, Ojida, Akio, Koyanagi, Satoru, Ohdo, Shigehiro
Publicado 2016