Direct observation of ligand migration within human hemoglobin at work

por Shibayama, Naoya, Sato-Tomita, Ayana, Ohki, Mio, Ichiyanagi, Kouhei, Park, Sam-Yong
Publicado 2020

Homopiperazine Derivatives as a Novel Class of Proteasome Inhibitors with a Unique Mode of Proteasome Binding

por Kikuchi, Jiro, Shibayama, Naoya, Yamada, Satoshi, Wada, Taeko, Nobuyoshi, Masaharu, Izumi, Tohru, Akutsu, Miyuki, Kano, Yasuhiko, Sugiyama, Kanako, Ohki, Mio, Park, Sam-Yong, Furukawa, Yusuke
Publicado 2013

Troglitazone Impedes the Oligomerization of Sodium Taurocholate Cotransporting Polypeptide and Entry of Hepatitis B Virus Into Hepatocytes

por Fukano, Kento, Tsukuda, Senko, Oshima, Mizuki, Suzuki, Ryosuke, Aizaki, Hideki, Ohki, Mio, Park, Sam-Yong, Muramatsu, Masamichi, Wakita, Takaji, Sureau, Camille, Ogasawara, Yuki, Watashi, Koichi
Publicado 2019

Computational design of a symmetrical β-trefoil lectin with cancer cell binding activity

por Terada, Daiki, Voet, Arnout R. D., Noguchi, Hiroki, Kamata, Kenichi, Ohki, Mio, Addy, Christine, Fujii, Yuki, Yamamoto, Daiki, Ozeki, Yasuhiro, Tame, Jeremy R. H., Zhang, Kam Y. J.
Publicado 2017

Pumping mechanism of NM-R3, a light-driven bacterial chloride importer in the rhodopsin family

por Yun, Ji-Hye, Ohki, Mio, Park, Jae-Hyun, Ishimoto, Naito, Sato-Tomita, Ayana, Lee, Wonbin, Jin, Zeyu, Tame, Jeremy R. H., Shibayama, Naoya, Park, Sam-Yong, Lee, Weontae
Publicado 2020

Structural basis for ligand recognition and signaling of hydroxy-carboxylic acid receptor 2

por Park, Jae-Hyun, Kawakami, Kouki, Ishimoto, Naito, Ikuta, Tatsuya, Ohki, Mio, Ekimoto, Toru, Ikeguchi, Mitsunori, Lee, Dong-Sun, Lee, Young-Ho, Tame, Jeremy R. H., Inoue, Asuka, Park, Sam-Yong
Publicado 2023

Structure of the human galanin receptor 2 bound to galanin and Gq reveals the basis of ligand specificity and how binding affects the G-protein interface

por Heo, Yunseok, Ishimoto, Naito, Jeon, Ye-Eun, Yun, Ji-Hye, Ohki, Mio, Anraku, Yuki, Sasaki, Mina, Kita, Shunsuke, Fukuhara, Hideo, Ikuta, Tatsuya, Kawakami, Kouki, Inoue, Asuka, Maenaka, Katsumi, Tame, Jeremy R. H., Lee, Weontae, Park, Sam-Yong
Publicado 2022

Structural insights into the HBV receptor and bile acid transporter NTCP

por Park, Jae-Hyun, Iwamoto, Masashi, Yun, Ji-Hye, Uchikubo-Kamo, Tomomi, Son, Donghwan, Jin, Zeyu, Yoshida, Hisashi, Ohki, Mio, Ishimoto, Naito, Mizutani, Kenji, Oshima, Mizuki, Muramatsu, Masamichi, Wakita, Takaji, Shirouzu, Mikako, Liu, Kehong, Uemura, Tomoko, Nomura, Norimichi, Iwata, So, Watashi, Koichi, Tame, Jeremy R. H., Nishizawa, Tomohiro, Lee, Weontae, Park, Sam-Yong
Publicado 2022

Early-stage dynamics of chloride ion–pumping rhodopsin revealed by a femtosecond X-ray laser

por Yun, Ji-Hye, Li, Xuanxuan, Yue, Jianing, Park, Jae-Hyun, Jin, Zeyu, Li, Chufeng, Hu, Hao, Shi, Yingchen, Pandey, Suraj, Carbajo, Sergio, Boutet, Sébastien, Hunter, Mark S., Liang, Mengning, Sierra, Raymond G., Lane, Thomas J., Zhou, Liang, Weierstall, Uwe, Zatsepin, Nadia A., Ohki, Mio, Tame, Jeremy R. H., Park, Sam-Yong, Spence, John C. H., Zhang, Wenkai, Schmidt, Marius, Lee, Weontae, Liu, Haiguang
Publicado 2021