A G-quadruplex-binding compound shows potent activity in human gemcitabine-resistant pancreatic cancer cells

por Ahmed, Ahmed Abdullah, Marchetti, Chiara, Ohnmacht, Stephan A., Neidle, Stephen
Publicado 2020

KRAS oncogene repression in colon cancer cell lines by G-quadruplex binding indolo[3,2-c]quinolines

por Lavrado, João, Brito, Hugo, Borralho, Pedro M., Ohnmacht, Stephan A., Kim, Nam-Soon, Leitão, Clara, Pisco, Sílvia, Gunaratnam, Mekala, Rodrigues, Cecília M. P., Moreira, Rui, Neidle, Stephen, Paulo, Alexandra
Publicado 2015

Targeting KRAS Oncogene in Colon Cancer Cells with 7-Carboxylate Indolo[3,2-b]quinoline Tri-Alkylamine Derivatives

por Brito, Hugo, Martins, Ana Cláudia, Lavrado, João, Mendes, Eduarda, Francisco, Ana Paula, Santos, Sofia A., Ohnmacht, Stephan A., Kim, Nam-Soon, Rodrigues, Cecília M. P., Moreira, Rui, Neidle, Stephen, Borralho, Pedro M., Paulo, Alexandra
Publicado 2015

A G-quadruplex-binding compound showing anti-tumour activity in an in vivo model for pancreatic cancer

por Ohnmacht, Stephan A, Marchetti, Chiara, Gunaratnam, Mekala, Besser, Rachael J, Haider, Shozeb M, Di Vita, Gloria, Lowe, Helen L, Mellinas-Gomez, Maria, Diocou, Seckou, Robson, Mathew, Šponer, Jiri, Islam, Barira, Barbara Pedley, R, Hartley, John A, Neidle, Stephen
Publicado 2015

Targeting Multiple Effector Pathways in Pancreatic Ductal Adenocarcinoma with a G-Quadruplex-Binding Small Molecule

por Marchetti, Chiara, Zyner, Katherine G., Ohnmacht, Stephan A., Robson, Mathew, Haider, Shozeb M., Morton, Jennifer P., Marsico, Giovanni, Vo, Tam, Laughlin-Toth, Sarah, Ahmed, Ahmed A., Di Vita, Gloria, Pazitna, Ingrida, Gunaratnam, Mekala, Besser, Rachael J., Andrade, Ana C. G., Diocou, Seckou, Pike, Jeremy A., Tannahill, David, Pedley, R. Barbara, Evans, T. R. Jeffry, Wilson, W. David, Balasubramanian, Shankar, Neidle, Stephen
Publicado 2018