Relationship between Protein Levels and Gene Expression of Dihydropyrimidine Dehydrogenase in Human Tumor Cells during Growth in Culture and in Nude Mice

por Takechi, Teiji, Okabe, Hiroyuki, Fujioka, Akio, Murakami, Yuko, Fukushima, Masakazu
Publicado 1998

Effective Sequential Combined Chemotherapy with Trifluridine/Tipiracil and Regorafenib in Human Colorectal Cancer Cells

por Matsuoka, Kazuaki, Nakagawa, Fumio, Tanaka, Nozomu, Okabe, Hiroyuki, Matsuo, Kenichi, Takechi, Teiji
Publicado 2018

Expression of Thymidylate Synthase in Human Non‐small Cell Lung Cancer

por Otake, Yosuke, Tanaka, Fumihiro, Yanagihara, Kazuhiro, Hitomi, Shigeki, Okabe, Hiroyuki, Fukushima, Masakazu, Wada, Hiromi
Publicado 1999

Efficacy of combination chemotherapy using a novel oral chemotherapeutic agent, TAS-102, together with bevacizumab, cetuximab, or panitumumab on human colorectal cancer xenografts

por TSUKIHARA, HIROSHI, NAKAGAWA, FUMIO, SAKAMOTO, KAZUKI, ISHIDA, KEIJI, TANAKA, NOZOMU, OKABE, HIROYUKI, UCHIDA, JUNJI, MATSUO, KENICHI, TAKECHI, TEIJI
Publicado 2015

Sensitivity of Human Cancer Cells to the New Anticancer Ribo‐nucleoside TAS–106 Is Correlated with Expression of Uridine‐cytidine Kinase 2

por Shimamoto, Yuji, Koizumi, Katsuhisa, Okabe, Hiroyuki, Kazuno, Hiromi, Murakami, Yuko, Nakagawa, Fumio, Matsuda, Akira, Sasaki, Takuma, Fukushima, Masakazu
Publicado 2002

Dihydropyrimidine Dehydrogenase and Messenger RNA Levels in Gastric Cancer: Possible Predictor for Sensitivity to 5‐Fluorouracil

por Ishikawa, Yoichiro, Kubota, Tetsuro, Otani, Yoshihide, Watanabe, Masahiko, Teramoto, Tatsuo, Kumai, Koichiro, Takechi, Teiji, Okabe, Hiroyuki, Fukushima, Masakazu, Kitajima, Masaki
Publicado 2000

Crucial roles of thymidine kinase 1 and deoxyUTPase in incorporating the antineoplastic nucleosides trifluridine and 2′-deoxy-5-fluorouridine into DNA

por SAKAMOTO, KAZUKI, YOKOGAWA, TATSUSHI, UENO, HIROYUKI, OGUCHI, KEI, KAZUNO, HIROMI, ISHIDA, KEIJI, TANAKA, NOZOMU, OSADA, AKIKO, YAMADA, YUKARI, OKABE, HIROYUKI, MATSUO, KENICHI
Publicado 2015

Repeated oral dosing of TAS-102 confers high trifluridine incorporation into DNA and sustained antitumor activity in mouse models

por TANAKA, NOZOMU, SAKAMOTO, KAZUKI, OKABE, HIROYUKI, FUJIOKA, AKIO, YAMAMURA, KEISUKE, NAKAGAWA, FUMIO, NAGASE, HIDEKI, YOKOGAWA, TATSUSHI, OGUCHI, KEI, ISHIDA, KEIJI, OSADA, AKIKO, KAZUNO, HIROMI, YAMADA, YUKARI, MATSUO, KENICHI
Publicado 2014