Identification of novel juvenile-hormone signaling activators via high-throughput screening with a chemical library

por Kayukawa, Takumi, Furuta, Kenjiro, Yonesu, Kiyoaki, Okabe, Takayoshi
Publicado 2021

Identification of a juvenile-hormone signaling inhibitor via high-throughput screening of a chemical library

por Kayukawa, Takumi, Furuta, Kenjiro, Nagamine, Keisuke, Shinoda, Tetsuro, Yonesu, Kiyoaki, Okabe, Takayoshi
Publicado 2020

BE‐23372M, a Novel and Specific Inhibitor for Epidermal Growth Factor Receptor Kinase

por Tanaka, Seiichi, Okabe, Takayoshi, Chieda, Shinya, Endo, Kaori, Kanoh, Tomoko, Okura, Akira, Yoshida, Eisaku
Publicado 1994

A Proposal for a Structural Model of the Feline Calicivirus Protease Bound to the Substrate Peptide under Physiological Conditions

por Yokoyama, Masaru, Oka, Tomoichiro, Takagi, Hirotaka, Kojima, Hirotatsu, Okabe, Takayoshi, Nagano, Tetsuo, Tohya, Yukinobu, Sato, Hironori
Publicado 2017

Roles of peptidyl prolyl isomerase Pin1 in viral propagation

por Kanna, Machi, Nakatsu, Yusuke, Yamamotoya, Takeshi, Encinas, Jeffrey, Ito, Hisanaka, Okabe, Takayoshi, Asano, Tomoichiro, Sakaguchi, Takemasa
Publicado 2022

Oxytocin/vasopressin-like peptide inotocin regulates cuticular hydrocarbon synthesis and water balancing in ants

por Koto, Akiko, Motoyama, Naoto, Tahara, Hiroki, McGregor, Sean, Moriyama, Minoru, Okabe, Takayoshi, Miura, Masayuki, Keller, Laurent
Publicado 2019

Drug cytotoxicity screening using human intestinal organoids propagated with extensive cost-reduction strategies

por Takahashi, Yu, Inoue, Yu, Sato, Shintaro, Okabe, Takayoshi, Kojima, Hirotatsu, Kiyono, Hiroshi, Shimizu, Makoto, Yamauchi, Yoshio, Sato, Ryuichiro
Publicado 2023

Development of pathway-oriented screening to identify compounds to control 2-methylglyoxal metabolism in tumor cells

por Yanagi, Kouichi, Komatsu, Toru, Fujikawa, Yuuta, Kojima, Hirotatsu, Okabe, Takayoshi, Nagano, Tetsuo, Ueno, Tasuku, Hanaoka, Kenjiro, Urano, Yasuteru
Publicado 2023

Structural Basis for Specific Recognition of Substrates by Sapovirus Protease

por Yokoyama, Masaru, Oka, Tomoichiro, Kojima, Hirotatsu, Nagano, Tetsuo, Okabe, Takayoshi, Katayama, Kazuhiko, Wakita, Takaji, Kanda, Tadahito, Sato, Hironori
Publicado 2012

Small-Molecule-Induced Activation of Cellular Respiration Inhibits Biofilm Formation and Triggers Metabolic Remodeling in Staphylococcus aureus

por Okuda, Ken-ichi, Yamada-Ueno, Satomi, Yoshii, Yutaka, Nagano, Tetsuo, Okabe, Takayoshi, Kojima, Hirotatsu, Mizunoe, Yoshimitsu, Kinjo, Yuki
Publicado 2022

An HTRF based high-throughput screening for discovering chemical compounds that inhibit the interaction between Trypanosoma brucei Pex5p and Pex14p

por Watanabe, Yuichi, Kawaguchi, Kosuke, Saito, Syuken, Okabe, Takayoshi, Yonesu, Kiyoaki, Egashira, Shinichiro, Kameya, Masafumi, Morita, Masashi, Kashiwayama, Yoshinori, Imanaka, Tsuneo
Publicado 2016

Prolyl isomerase Pin1 plays an essential role in SARS-CoV-2 proliferation, indicating its possibility as a novel therapeutic target

por Yamamotoya, Takeshi, Nakatsu, Yusuke, Kanna, Machi, Hasei, Shun, Ohata, Yukino, Encinas, Jeffrey, Ito, Hisanaka, Okabe, Takayoshi, Asano, Tomoichiro, Sakaguchi, Takemasa
Publicado 2021

Organoid-derived intestinal epithelial cells are a suitable model for preclinical toxicology and pharmacokinetic studies

por Takahashi, Yu, Noguchi, Makoto, Inoue, Yu, Sato, Shintaro, Shimizu, Makoto, Kojima, Hirotatsu, Okabe, Takayoshi, Kiyono, Hiroshi, Yamauchi, Yoshio, Sato, Ryuichiro
Publicado 2022

Selective inhibitors of a PAF biosynthetic enzyme lysophosphatidylcholine acyltransferase 2

por Tarui, Megumi, Shindou, Hideo, Kumagai, Kazuo, Morimoto, Ryo, Harayama, Takeshi, Hashidate, Tomomi, Kojima, Hirotatsu, Okabe, Takayoshi, Nagano, Tetsuo, Nagase, Takahide, Shimizu, Takao
Publicado 2014

High-throughput Screening of Small Molecule Inhibitors of the Streptococcus Quorum-sensing Signal Pathway

por Ishii, Seiji, Fukui, Kenji, Yokoshima, Satoshi, Kumagai, Kazuo, Beniyama, Youko, Kodama, Tetsuya, Fukuyama, Tohru, Okabe, Takayoshi, Nagano, Tetsuo, Kojima, Hirotatsu, Yano, Takato
Publicado 2017

Norgestimate inhibits staphylococcal biofilm formation and resensitizes methicillin-resistant Staphylococcus aureus to β-lactam antibiotics

por Yoshii, Yutaka, Okuda, Ken-ichi, Yamada, Satomi, Nagakura, Mari, Sugimoto, Shinya, Nagano, Tetsuo, Okabe, Takayoshi, Kojima, Hirotatsu, Iwamoto, Takeo, Kuwano, Kazuyoshi, Mizunoe, Yoshimitsu
Publicado 2017

Author Correction: Norgestimate inhibits staphylococcal biofilm formation and resensitizes methicillin-resistant Staphylococcus aureus to β-lactam antibiotics

por Yoshii, Yutaka, Okuda, Ken-ichi, Yamada, Satomi, Nagakura, Mari, Sugimoto, Shinya, Nagano, Tetsuo, Okabe, Takayoshi, Kojima, Hirotatsu, Iwamoto, Takeo, Kuwano, Kazuyoshi, Mizunoe, Yoshimitsu
Publicado 2017

Pathological Role of Pin1 in the Development of DSS-Induced Colitis

por Matsunaga, Yasuka, Hasei, Shun, Yamamotoya, Takeshi, Honda, Hiroaki, Kushiyama, Akifumi, Sakoda, Hideyuki, Fujishiro, Midori, Ono, Hiraku, Ito, Hisanaka, Okabe, Takayoshi, Asano, Tomoichiro, Nakatsu, Yusuke
Publicado 2021

Non-steroidal inhibitors of Drosophila melanogaster steroidogenic glutathione S-transferase Noppera-bo

por Koiwai, Kotaro, Morohashi, Kana, Inaba, Kazue, Ebihara, Kana, Kojima, Hirotatsu, Okabe, Takayoshi, Yoshino, Ryunosuke, Hirokawa, Takatsugu, Nampo, Taiki, Fujikawa, Yuuta, Inoue, Hideshi, Yumoto, Fumiaki, Senda, Toshiya, Niwa, Ryusuke
Publicado 2021

Dephospho-Coenzyme A Kinase Is an Exploitable Drug Target against Plasmodium falciparum: Identification of Selective Inhibitors by High-Throughput Screening of a Large Chemical Com...

por Nurkanto, Arif, Imamura, Riyo, Rahmawati, Yulia, Prabandari, Erwahyuni Endang, Waluyo, Danang, Annoura, Takeshi, Yamamoto, Kazuki, Sekijima, Masakazu, Nishimura, Yuki, Okabe, Takayoshi, Shiba, Tomoo, Shibata, Norio, Kojima, Hirotatsu, Duffy, James, Nozaki, Tomoyoshi
Publicado 2022