GSK3 inhibition circumvents and overcomes acquired lorlatinib resistance in ALK-rearranged non-small-cell lung cancer

por Shimizu, Yuki, Okada, Koutaroh, Adachi, Jun, Abe, Yuichi, Narumi, Ryohei, Uchibori, Ken, Yanagitani, Noriko, Koike, Sumie, Takagi, Satoshi, Nishio, Makoto, Fujita, Naoya, Katayama, Ryohei
Publicado 2022

Overcoming resistance by ALK compound mutation (I1171S + G1269A) after sequential treatment of multiple ALK inhibitors in non‐small cell lung cancer

por Takahashi, Ken, Seto, Yosuke, Okada, Koutaroh, Uematsu, Shinya, Uchibori, Ken, Tsukahara, Mika, Oh‐hara, Tomoko, Fujita, Naoya, Yanagitani, Noriko, Nishio, Makoto, Okubo, Kenichi, Katayama, Ryohei
Publicado 2020

Prediction of ALK mutations mediating ALK-TKIs resistance and drug re-purposing to overcome the resistance

por Okada, Koutaroh, Araki, Mitsugu, Sakashita, Takuya, Ma, Biao, Kanada, Ryo, Yanagitani, Noriko, Horiike, Atsushi, Koike, Sumie, Oh-hara, Tomoko, Watanabe, Kana, Tamai, Keiichi, Maemondo, Makoto, Nishio, Makoto, Ishikawa, Takeshi, Okuno, Yasushi, Fujita, Naoya, Katayama, Ryohei
Publicado 2019

Gilteritinib overcomes lorlatinib resistance in ALK-rearranged cancer

por Mizuta, Hayato, Okada, Koutaroh, Araki, Mitsugu, Adachi, Jun, Takemoto, Ai, Kutkowska, Justyna, Maruyama, Kohei, Yanagitani, Noriko, Oh-hara, Tomoko, Watanabe, Kana, Tamai, Keiichi, Friboulet, Luc, Katayama, Kazuhiro, Ma, Biao, Sasakura, Yoko, Sagae, Yukari, Kukimoto-Niino, Mutsuko, Shirouzu, Mikako, Takagi, Satoshi, Simizu, Siro, Nishio, Makoto, Okuno, Yasushi, Fujita, Naoya, Katayama, Ryohei
Publicado 2021

HER3 activation contributes toward the emergence of ALK inhibitor-tolerant cells in ALK-rearranged lung cancer with mesenchymal features

por Tanimura, Keiko, Yamada, Tadaaki, Okada, Koutaroh, Nakai, Kunihiro, Horinaka, Mano, Katayama, Yuki, Morimoto, Kenji, Ogura, Yuri, Takeda, Takayuki, Shiotsu, Shinsuke, Ichikawa, Kosuke, Watanabe, Satoshi, Morimoto, Yoshie, Iwasaku, Masahiro, Kaneko, Yoshiko, Uchino, Junji, Taniguchi, Hirokazu, Yoneda, Kazue, Matoba, Satoaki, Sakai, Toshiyuki, Uehara, Hisanori, Yano, Seiji, Kusaba, Tetsuro, Katayama, Ryohei, Takayama, Koichi
Publicado 2022