Trimethylamine N-oxide in atrial fibrillation progression

por Büttner, Petra, Okun, Jürgen G., Hauke, Jana, Holzwirth, Erik, Obradovic, Danilo, Hindricks, Gerhard, Thiele, Holger, Kornej, Jelena
Publicado 2020

Potential of blood-based biomarker approaches in endometrium and breast cancer: a case-control comparison study

por Schuhn, Anne, Tobar, Tania Witte, Gahlawat, Aoife Ward, Hauke, Jana, Baumann, Lukas, Okun, Jürgen G., Nees, Juliane
Publicado 2022

Blood Trimethylamine-N-Oxide Originates from Microbiota Mediated Breakdown of Phosphatidylcholine and Absorption from Small Intestine

por Stremmel, Wolfgang, Schmidt, Kathrin V., Schuhmann, Vera, Kratzer, Frank, Garbade, Sven F., Langhans, Claus-Dieter, Fricker, Gert, Okun, Jürgen G.
Publicado 2017

Identification of neurodegeneration indicators and disease progression in metachromatic leukodystrophy using quantitative NMR‐based urinary metabolomics

por Laugwitz, Lucia, Zizmare, Laimdota, Santhanakumaran, Vidiyaah, Cannet, Claire, Böhringer, Judith, Okun, Jürgen G., Spraul, Manfred, Krägeloh‐Mann, Ingeborg, Groeschel, Samuel, Trautwein, Christoph
Publicado 2022

A high-throughput newborn screening approach for SCID, SMA, and SCD combining multiplex qPCR and tandem mass spectrometry

por Tesorero, Rafael, Janda, Joachim, Hörster, Friederike, Feyh, Patrik, Mütze, Ulrike, Hauke, Jana, Schwarz, Kathrin, Kunz, Joachim B., Hoffmann, Georg F., Okun, Jürgen G.
Publicado 2023

Simultaneous determination of 3-hydroxypropionic acid, methylmalonic acid and methylcitric acid in dried blood spots: Second-tier LC-MS/MS assay for newborn screening of propionic...

por Monostori, Péter, Klinke, Glynis, Richter, Sylvia, Baráth, Ákos, Fingerhut, Ralph, Baumgartner, Matthias R., Kölker, Stefan, Hoffmann, Georg F., Gramer, Gwendolyn, Okun, Jürgen G.
Publicado 2017

QDPR homologues in Danio rerio regulate melanin synthesis, early gliogenesis, and glutamine homeostasis

por Breuer, Maximilian, Guglielmi, Luca, Zielonka, Matthias, Hemberger, Verena, Kölker, Stefan, Okun, Jürgen G., Hoffmann, Georg F., Carl, Matthias, Sauer, Sven W., Opladen, Thomas
Publicado 2019

Extended diagnosis of purine and pyrimidine disorders from urine: LC MS/MS assay development and clinical validation

por Monostori, Péter, Klinke, Glynis, Hauke, Jana, Richter, Sylvia, Bierau, Jörgen, Garbade, Sven F., Hoffmann, Georg F., Langhans, Claus-Dieter, Haas, Dorothea, Okun, Jürgen G.
Publicado 2019

Trimethylamine-N-Oxide Levels Are Similar in Asymptomatic vs. Symptomatic Cerebrovascular Atherosclerosis

por Heyse, Miriam, Schneider, Christine, Monostori, Peter, Schwarz, Kathrin V., Hauke, Jana, Drüschler, Katharina, Berberich, Anne, Zorn, Markus, Ringleb, Peter A., Okun, Jürgen G., Mundiyanapurath, Sibu
Publicado 2021

Differences of Phenylalanine Concentrations in Dried Blood Spots and in Plasma: Erythrocytes as a Neglected Component for This Observation

por Haas, Dorothea, Hauke, Jana, Schwarz, Kathrin V., Consalvi, Lucia, Trefz, Friedrich K., Blau, Nenad, Hoffmann, Georg F., Burgard, Peter, Garbade, Sven F., Okun, Jürgen G.
Publicado 2021

High Throughput Newborn Screening for Sickle Cell Disease – Application of Two-Tiered Testing with a qPCR-Based Primary screen

por Janda, Joachim, Hegert, Sebastian, Bzdok, Jessica, Tesorero, Rafael, Holtkamp, Ute, Burggraf, Siegfried, Schuhmann, Elfriede, Hörster, Friedrike, Hoffmann, Georg F., Janzen, Nils, Okun, Jürgen G, Becker, Marc, Durner, Jürgen
Publicado 2023

Dietary stearic acid regulates mitochondria in vivo in humans

por Senyilmaz-Tiebe, Deniz, Pfaff, Daniel H., Virtue, Sam, Schwarz, Kathrin V., Fleming, Thomas, Altamura, Sandro, Muckenthaler, Martina U., Okun, Jürgen G., Vidal-Puig, Antonio, Nawroth, Peter, Teleman, Aurelio A.
Publicado 2018

Molecular regulation of urea cycle function by the liver glucocorticoid receptor

por Okun, Jürgen G., Conway, Sean, Schmidt, Kathrin V., Schumacher, Jonas, Wang, Xiaoyue, de Guia, Roldan, Zota, Annika, Klement, Johanna, Seibert, Oksana, Peters, Achim, Maida, Adriano, Herzig, Stephan, Rose, Adam J.
Publicado 2015

Corrigendum to “Molecular regulation of urea cycle function by the liver glucocorticoid receptor” [Mol Metab 4 (10) (2015 Oct) 732–740]

por Okun, Jürgen G., Conway, Sean, Schmidt, Kathrin V., Schumacher, Jonas, Wang, Xiaoyue, de Guia, Roldan, Zota, Annika, Klement, Johanna, Seibert, Oksana, Peters, Achim, Maida, Adriano, Herzig, Stephan, Rose, Adam J.
Publicado 2020

mRNA-based therapy proves superior to the standard of care for treating hereditary tyrosinemia 1 in a mouse model

por Cacicedo, Maximiliano L., Weinl-Tenbruck, Christine, Frank, Daniel, Wirsching, Sebastian, Straub, Beate K., Hauke, Jana, Okun, Jürgen G., Horscroft, Nigel, Hennermann, Julia B., Zepp, Fred, Chevessier-Tünnesen, Frédéric, Gehring, Stephan
Publicado 2022

Angiocrine Wnt signaling controls liver growth and metabolic maturation in mice

por Leibing, Thomas, Géraud, Cyrill, Augustin, Iris, Boutros, Michael, Augustin, Hellmut G., Okun, Jürgen G., Langhans, Claus‐Dieter, Zierow, Johanna, Wohlfeil, Sebastian A., Olsavszky, Victor, Schledzewski, Kai, Goerdt, Sergij, Koch, Philipp‐Sebastian
Publicado 2018

Crystal structure and interaction studies of human DHTKD1 provide insight into a mitochondrial megacomplex in lysine catabolism

por Bezerra, Gustavo A., Foster, William R., Bailey, Henry J., Hicks, Kevin G., Sauer, Sven W., Dimitrov, Bianca, McCorvie, Thomas J., Okun, Jürgen G., Rutter, Jared, Kölker, Stefan, Yue, Wyatt W.
Publicado 2020

Predicting the disease severity in male individuals with ornithine transcarbamylase deficiency

por Scharre, Svenja, Posset, Roland, Garbade, Sven F., Gleich, Florian, Seidl, Marie J., Druck, Ann‐Catrin, Okun, Jürgen G., Gropman, Andrea L., Nagamani, Sandesh C. S., Hoffmann, Georg F., Kölker, Stefan, Zielonka, Matthias
Publicado 2022

Combined Newborn Screening Allows Comprehensive Identification also of Attenuated Phenotypes for Methylmalonic Acidurias and Homocystinuria

por Schnabel, Elena, Kölker, Stefan, Gleich, Florian, Feyh, Patrik, Hörster, Friederike, Haas, Dorothea, Fang-Hoffmann, Junmin, Morath, Marina, Gramer, Gwendolyn, Röschinger, Wulf, Garbade, Sven F., Hoffmann, Georg F., Okun, Jürgen G., Mütze, Ulrike
Publicado 2023

Assessment of methylcitrate and methylcitrate to citrate ratio in dried blood spots as biomarkers for inborn errors of propionate metabolism

por Al-Dirbashi, Osama Y., Alfadhel, Majid, Al-Thihli, Khalid, Al Dhahouri, Nahid, Langhans, Claus-Dieter, Al Hammadi, Zalikha, Al-Shamsi, Aisha, Hertecant, Jozef, Okun, Jürgen G., Hoffmann, Georg F., Al-Jasmi, Fatma
Publicado 2019